Innovative Green Synthesis and Multifunctional Applications of Pyrimidopyrimidine Derivatives [0.03%]
嘧啶并嘧啶衍生物的绿色合成及多功能应用研究
Ruchi Bharti,Ankita Thakral,Ajay Thakur et al.
Ruchi Bharti et al.
Introduction: This research introduces an eco-friendly, one-pot multicomponent synthesis of pyrimidopyrimidines (4a-4i) and amino-1,3-dimethylpyrimidines (5a-5d) in an aqueous medium, utilizing citric acid as a catalyst. ...
Unveiling New Process Impurities in Ripasudil Hydrochloride Dihydrate: Identification, Synthesis, and Characterization [0.03%]
润帕素地 hydrate中的新工艺杂质的研究：分离、合成和表征
Kedarnath M Birajdar,Sudhakar Arrahalli,Praveen Beekanhalli Mokshanatha et al.
Kedarnath M Birajdar et al.
Background: Ripasudil hydrochloride or 4-Fluoro-5-{[(2S)-2-Methyl-1,4- diazepan-1-yl] sulfonyl isoquinoline hydrochloride known as K-115 is used for the treatment of glaucoma and ocular hypertension. In the API industry, ...
A Decade of Catalytic Progress in 1,4-Dihydropyridines (1,4-DHPs) Synthesis (2016-2024) [0.03%]
过去十年一氧化氮供体类药物1,4-二氢吡啶类化合物的催化合成进展(2016-2024)
Aditi Soni,Monika Sharma,Rajesh K Singh
Aditi Soni
1,4-Dihydropyridines (1,4-DHPs) are highly versatile and bioactive compounds known for their pharmacological properties, including cardiovascular, anticancer, and antioxidant activities. Traditional synthesis methods often involve harsh con...
Efficient Formylation of Alcohols Using a Core-Shell Magnetic Nanocomposite Via Vilsmeier-Haack Complex Formation [0.03%]
利用维尔施梅尔-哈克复合物法高效甲醛化醇类化合物
Farzaneh Ebrahimzadeh
Farzaneh Ebrahimzadeh
Introduction: The protection of the hydroxyl group as formamides is a crucial initial step in pharmaceutical synthesis. Methods: In thi...
Synthesis of Novel Derivatives of 4,6-Diarylpyrimidines and Dihydro-Pyrimidin-4-one and In Silico Screening of Their Anticancer Activity [0.03%]
新型4,6-二芳基嘧啶和四氢-嘧啶衍生物的合成及其抗肿瘤活性的计算机辅助筛选研究
Oleksandr V Onipko,Veronika Stoianova,Oleksandr V Buravov et al.
Oleksandr V Onipko et al.
Derivatives of pyrimidinone, dihydropyrimidinone, and 2,4-diaryl-substituted pyrimidines were synthesized by cyclocondensation of α-aminoamidines with various saturated carbonyl derivatives and their analogs. The therapeutic potential of t...
Konsalraj Julietraja,Arul Amirtha Raja Susai,Ammar Alsinai
Konsalraj Julietraja
Background: Sodalite is a type of zeolite with an intricate structure comprising a system of interrelated cages and tunnels. It is extensively used in sieving applications due to its unique structure and properties. As a ...
Synthesis and Development of Suitable Method for New Thiadiazoles using Hydrazonoyl Halides [0.03%]
含胲卤醛类化合物合成新型噻二唑的方法研究与发展
Munirah F Alarbash,Yasair S Al-Faiyz,Jeffrey S Wiggins et al.
Munirah F Alarbash et al.
Background: Hydrazonoyl halides and methylhydrazinecarbodithioate have been generally utilized in the synthesis of heterocycles. Methods: ...
Synthesis of Heterocyclic Sulfonium Triflates by Cu-catalyzed Selective S-arylation with Aryl(mesityl)iodonium Salts [0.03%]
铜催化下与芳基(三环己基甲基)碘鎓盐的选择性S-芳基化反应合成杂环锍三氟甲磺酸盐
Yusuke Yoto,Ryo Hatagochi,Yuto Irie et al.
Yusuke Yoto et al.
Background: An efficient method for synthesizing cyclic arylsulfonium salts has been developed by selective aryl transfer to the sulfur atom from aryl(mesityl)iodonium triflates, a recyclable series of diaryliodonium salt...
Multidimensional Uses of Bitter Melon (Momordica charantia L.) Considering the Important Functions of its Chemical Components [0.03%]
苦瓜(Momordica charantia L.)的多维度利用及其化学成分的重要功能考虑
Mohamad Hesam Shahrajabian,Wenli Sun
Mohamad Hesam Shahrajabian
Bitter melon (Momordica charantia L.) is a member of the Cucurbitaceae, which is also known as bitter squash, bitter gourd, karela, Goya melon and balsam pear. It is a rich source of different vitamins, potassium, zinc and other nutrients. ...
Aisha M Alateeq,Yasair S Al-Faiyz,Olivia D McNair et al.
Aisha M Alateeq et al.
The current review aimed to provide an understanding of the preparation, reactions, and biological action of thiazoles. The purpose of this review was to focus on the progress made in the synthesis of physiologically effective thiazole prod...