Oxygen and TGF-β1 jointly regulate fibronectin and trophoblast behavior highlighting a potential role for matrix signalingin severe preeclampsia [0.03%]
氧和TGF-β1联合调节纤维连接蛋白和滋养层细胞行为表明基质信号在重度子痫前期中可能发挥作用
Felipe Gallardo,Delia I Chiarello,Ivo Carrasco-Wong et al.
Felipe Gallardo et al.
Fibronectin is a key component of the extracellular matrix whose abundance and organization depend on both environmental conditions and intracellular signaling. In this study we show that oxygen tension modifies the response of extravillous...
Amelogenin proteolysis orchestrates functional amyloid pathways in enamel development [0.03%]
釉基质蛋白酶学使牙釉质发育过程中的功能淀粉样途径有序化
Emerson Tavares de Sousa,Larry Ackerman,Johan Svensson Bonde et al.
Emerson Tavares de Sousa et al.
Amelogenin, the most abundant protein in developing enamel, self-assembles into supramolecular structures that serve as templates for apatite growth. Recent studies revealed that amelogenin nanoribbons exhibit hallmark features of functiona...
Corrigendum to "Laminin-511-functionalized fibrin gel enables in-gel proliferation of human induced pluripotent stem cells" [Matrix Biology Volume 142, December 2025, Pages 21-32] [0.03%]
关于“层粘连蛋白-511功能化纤黏蛋白凝胶使人类诱导多能干细胞在凝胶内增殖”一文的勘误(矩阵生物学杂志第142卷，2025年12月，21-32页)
Yukimasa Taniguchi,Mamoru Takizawa,Ayaka Hada et al.
Yukimasa Taniguchi et al.
Follow the science: How fat cells taught us about scarring and ECM homeostasis [0.03%]
听从科学：脂肪细胞如何教会我们了解瘢痕和基质稳态
Valerie Horsley
Valerie Horsley
This article describes the journey of my laboratory team as we became fascinated in the dynamic changes that occurred to adipose tissue in the skin during tissue injury and fibrosis. I discuss how lineage tracing and molecular manipulation ...
α-Dystroglycan at the ECM-Cell crossroad: emerging functions of its N-terminal domain [0.03%]
位于细胞外基质-细胞交叉路口的α-连环蛋白：其N端结构域的新功能
Maria Giulia Bigotti,Andrea Brancaccio
Maria Giulia Bigotti
Dystroglycan plays a crucial role for cell to extracellular matrix (ECM) adhesiveness in a plethora of different tissues and physio-pathological conditions. It belongs to the dystrophin-glycoprotein complex, whose overall structure has been...
Liver-derived, circulating plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men [0.03%]
肝源性循环血浆纤维连接蛋白调节雄性小鼠 trabecular骨量和成骨作用及其在老年男性血液中的水平与骨密度相关
Mahdokht Mahmoodi,Claudie Berger,Mir-Hamed Nabavi et al.
Mahdokht Mahmoodi et al.
Plasma fibronectin is a liver-derived glycoprotein that circulates at relatively high concentration and accumulates in tissues to form ECM. The role of plasma fibronectin in osteoblastogenesis, bone formation and remodeling has been suggest...
Human mammary 3D spheroid models uncover the role of filopodia in breaching the basement membrane to facilitate invasion [0.03%]
人乳球体模型揭示filopodia在突破基底膜以促进侵袭的作用
Alain Corinus,Sophie Abelanet,Julia Dubreuil et al.
Alain Corinus et al.
Basement membranes (BM) are thin, nanoporous sheets of specialized extracellular matrix (ECM) that line epithelial tissues. They are dynamic structures that serve multiple key functions, as evidenced by numerous diseases, including cancer p...
CCN1: a SASPy protein that plays multifaceted roles in fibrogenesis [0.03%]
CCN1：一种参与纤维化发生发展的多功能SASP蛋白
Andrew Leask
Andrew Leask
The matricellular protein CCN1 is pro-apoptotic, and can be considered as a possible inducer of the senescence-associated secretory phenotype (SASP). Although the SASP facilitates healthy tissue repair when apoptotic cells are properly clea...
High hyaluronan binding and RHAMM expression identify an invasive and metastatic subpopulation in androgen-resistant prostate cancer cells [0.03%]
高透明质酸结合和RHAMM表达可识别雄激素抵抗性前列腺癌细胞中的一类侵袭性和转移性亚群
Tolg C,Price M,Leith S et al.
Tolg C et al.
Hyaluronan (HA) metabolism in prostate cancer associates with androgen resistance and metastasis. We showed that binding of low molecular weight HA (≤250kDa) to castration-resistant prostate cancer cells was heterogeneous with most cells b...