Polyhydroxybutyrate nanoparticles for encapsulating carvacrol: release in food simulants, antimicrobial applications and human health potential [0.03%]
用于封装百里酚的聚羟基丁酸酯纳米颗粒：在食品模拟物中的释放、抗菌应用及对人体健康的影响
Ehira Romero-Castelán,Nayeli-Shantal Castrejón-Jiménez,Adriana-Inés Rodríguez-Hernández et al.
Ehira Romero-Castelán et al.
Biological food contamination is a serious public health and economic problem worldwide. Antibiotics are commonly used to address this issue, but rising bacterial resistance has sparked interest in natural alternatives, such as carvacrol. C...
In vivo assessment of rosmarinic acid phytosomes for concurrent antidiabetic and antihypertensive effects [0.03%]
肉桂酸植物体的体内评估及其协同降糖降压效果
Saraswati Prasad Mishra,Bibaswan Mishra,Sanjay Kumar Gupta et al.
Saraswati Prasad Mishra et al.
Diabetes mellitus and hypertension commonly coexist, creating a major global health challenge that requires therapies capable of targeting multiple pathological pathways simultaneously. This study evaluated the therapeutic potential of rosm...
Coaxially electrospun silk fibroin scaffold incorporating kartogenin via β-cyclodextrin for rotator cuff repair [0.03%]
通过β-环糊精将Kartogenin共轴静电纺入丝素蛋白支架用于肩袖修复
Qixiang Ping,Zhaojie Wang,Tao Yang et al.
Qixiang Ping et al.
Rotator cuff tears (RCT) constitute a prevalent and clinically challenging musculoskeletal pathology. Medications, such as anti-inflammatory drugs, only alleviate symptoms without addressing the underlying cause, and their delivery efficien...
Rational lipid screening for the development of solid lipid nanoparticles and nanostructured lipid carriers: formulation, characterization and in vitro evaluation [0.03%]
固体脂质纳米粒和结构脂质载体的合理脂质筛选：处方、表征及体外评价
Suriya Prakaash Kannan,Damodharan Narayanasamy
Suriya Prakaash Kannan
Sertraline hydrochloride, a selective serotonin reuptake inhibitor, suffers from poor aqueous solubility and extensive first-pass metabolism, limiting its oral bioavailability. Solid lipid nanoparticles (SLN) and nanostructured lipid carrie...
In vitro and in vivo evaluation of DNA-integrated diclofenac-HPMC hydrogel for enhanced ocular anti-inflammatory drug delivery [0.03%]
一种新型载有双氯芬酸钠的DNA-HPMC水凝胶的眼用制剂及其药效评价研究
Pratikeswar Panda,Snehanjana Biswal,Shreyashree Mohanty et al.
Pratikeswar Panda et al.
Ocular inflammation is a major ophthalmic disorder associated with redness, irritation, pain, and tissue damage, requiring effective and sustained drug delivery for improved therapeutic management. The present study aimed to develop and eva...
Fabrication of bi-layered bioresorbable ureteral stent and in-vitro analysis for sustained therapeutics [0.03%]
分层可吸收尿管支架的制备及体外分析以实现持续治疗作用
Eswara Rajagopal,Subhikssha Babu,Joyce Angel Jayakumar et al.
Eswara Rajagopal et al.
An effective stent for ureteral obstruction requires controlled swelling behaviour, sustained drug delivery, inhibition of bacterial adhesion, and performance characteristics that conventional stents frequently fail to attain. Two bi-layer ...
Recent advances in hydrogels loaded with plant-derived pure small molecules intervening in immune pathways to accelerate diabetic ulcer healing [0.03%]
负载植物来源的小分子干预免疫途径的水凝胶促进糖尿病溃疡愈合的研究进展
Shuhui Zheng,Lin Du,Cunming Lv
Shuhui Zheng
In the field of diabetic ulcer treatment, plant-derived pure small molecular compounds loaded in hydrogels have shown significant potential value and importance. However, existing literature on hydrogel dressings for the treatment of diabet...
Advances in nanocarrier-enabled theranostic strategies for lung cancer diagnosis and management [0.03%]
基于纳米载体的肺癌诊疗策略研究进展
Haard Mehta,Bindu Kumari N Yadav,Sheetal Acharya et al.
Haard Mehta et al.
Lung cancer continues to be a primary cause of cancer-related death globally, attributed to late-stage detection and the inadequate sensitivity of traditional diagnostic methods. Recent advances in nanotechnology have markedly enhanced earl...
Development of a multifunctional layered scaffold system to inhibit periodontal infection and promote bone regeneration: characterisation and in vitro evaluation [0.03%]
一种抑制牙周感染和促进骨再生的多功能层状支架系统的开发：表征与体外评估
Devika Sajeev,Abhirami Subramony,Julee Parihar et al.
Devika Sajeev et al.
The presented study deals with the design of a new, advanced combination treatment of periodontitis by developing a multi-functional layered scaffold system incorporating a polymeric gel with tetracycline hydrochloride and hydroxyapatite. I...
A comprehensive overview on bioutization of marine byssal protein: chemistry, characterization, and biomedical applications [0.03%]
海洋贝壳蛋白生物转化综述：化学、表征及医学应用
Karunanithi Masilan,Jeevithan Elango,Gresha Amstrong et al.
Karunanithi Masilan et al.
Marine molluscs produce a class of proteinaceous materials, byssal proteins that possess unique mechanical and adhesive properties. In this sense, the extraordinary adhesion of mussel byssal proteins is inspiring a new class of surgical glu...