Rational lipid screening for the development of solid lipid nanoparticles and nanostructured lipid carriers: formulation, characterization and in vitro evaluation
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Sertraline hydrochloride, a selective serotonin reuptake inhibitor, suffers from poor aqueous solubility and extensive first-pass metabolism, limiting its oral bioavailability. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) offer a via... ...
