Coaxial electrospun PCL/PVA core-shell nanofibrous scaffolds with green-synthesized AgNPs for release-regulated antibacterial activity [0.03%]
绿色合成的银纳米颗粒同轴静电纺丝PCL / PVA核壳纳米纤维支架用于调节抗菌性能
Amanullah,Mainul Islam,Md Mustafizur Rahman et al.
Amanullah et al.
This study developed coaxially electrospun polycaprolactone/polyvinyl alcohol (PCL/PVA) core-shell nanofibrous scaffolds incorporating green-synthesized silver nanoparticles (AgNPs) from Synedrella nodiflora as candidate antibacterial wound...
Wei Zhou,Jinhang Jiang,Yong-Chang Yao et al.
Wei Zhou et al.
Articular cartilage (AC) possesses complex depth-dependent gradients in cell phenotype, matrix composition, metabolism, mechanics, and growth factors. These natural gradients are essential for cartilage function. Because of lack of blood ve...
Nanogels as smart delivery systems for bioactive compounds in bone regeneration: a review [0.03%]
纳米凝胶作为骨再生中生物活性化合物的智能递送系统：综述
Saranya Srinivasan,Ashwathi Vijayalekha,Suresh Kumar Anandasadagopan et al.
Saranya Srinivasan et al.
Bone regeneration remains a critical challenge in tissue engineering and requires innovative strategies to promote the efficient healing and restoration of bone function. Nanogels have emerged as promising carriers for bioactive compounds i...
Polyhydroxybutyrate nanoparticles for encapsulating carvacrol: release in food simulants, antimicrobial applications and human health potential [0.03%]
用于封装百里酚的聚羟基丁酸酯纳米颗粒：在食品模拟物中的释放、抗菌应用及对人体健康的影响
Ehira Romero-Castelán,Nayeli-Shantal Castrejón-Jiménez,Adriana-Inés Rodríguez-Hernández et al.
Ehira Romero-Castelán et al.
Biological food contamination is a serious public health and economic problem worldwide. Antibiotics are commonly used to address this issue, but rising bacterial resistance has sparked interest in natural alternatives, such as carvacrol. C...
In vivo assessment of rosmarinic acid phytosomes for concurrent antidiabetic and antihypertensive effects [0.03%]
肉桂酸植物体的体内评估及其协同降糖降压效果
Saraswati Prasad Mishra,Bibaswan Mishra,Sanjay Kumar Gupta et al.
Saraswati Prasad Mishra et al.
Diabetes mellitus and hypertension commonly coexist, creating a major global health challenge that requires therapies capable of targeting multiple pathological pathways simultaneously. This study evaluated the therapeutic potential of rosm...
Coaxially electrospun silk fibroin scaffold incorporating kartogenin via β-cyclodextrin for rotator cuff repair [0.03%]
通过β-环糊精将Kartogenin共轴静电纺入丝素蛋白支架用于肩袖修复
Qixiang Ping,Zhaojie Wang,Tao Yang et al.
Qixiang Ping et al.
Rotator cuff tears (RCT) constitute a prevalent and clinically challenging musculoskeletal pathology. Medications, such as anti-inflammatory drugs, only alleviate symptoms without addressing the underlying cause, and their delivery efficien...
Rational lipid screening for the development of solid lipid nanoparticles and nanostructured lipid carriers: formulation, characterization and in vitro evaluation [0.03%]
固体脂质纳米粒和结构脂质载体的合理脂质筛选：处方、表征及体外评价
Suriya Prakaash Kannan,Damodharan Narayanasamy
Suriya Prakaash Kannan
Sertraline hydrochloride, a selective serotonin reuptake inhibitor, suffers from poor aqueous solubility and extensive first-pass metabolism, limiting its oral bioavailability. Solid lipid nanoparticles (SLN) and nanostructured lipid carrie...
In vitro and in vivo evaluation of DNA-integrated diclofenac-HPMC hydrogel for enhanced ocular anti-inflammatory drug delivery [0.03%]
一种新型载有双氯芬酸钠的DNA-HPMC水凝胶的眼用制剂及其药效评价研究
Pratikeswar Panda,Snehanjana Biswal,Shreyashree Mohanty et al.
Pratikeswar Panda et al.
Ocular inflammation is a major ophthalmic disorder associated with redness, irritation, pain, and tissue damage, requiring effective and sustained drug delivery for improved therapeutic management. The present study aimed to develop and eva...
Fabrication of bi-layered bioresorbable ureteral stent and in-vitro analysis for sustained therapeutics [0.03%]
分层可吸收尿管支架的制备及体外分析以实现持续治疗作用
Eswara Rajagopal,Subhikssha Babu,Joyce Angel Jayakumar et al.
Eswara Rajagopal et al.
An effective stent for ureteral obstruction requires controlled swelling behaviour, sustained drug delivery, inhibition of bacterial adhesion, and performance characteristics that conventional stents frequently fail to attain. Two bi-layer ...
Recent advances in hydrogels loaded with plant-derived pure small molecules intervening in immune pathways to accelerate diabetic ulcer healing [0.03%]
负载植物来源的小分子干预免疫途径的水凝胶促进糖尿病溃疡愈合的研究进展
Shuhui Zheng,Lin Du,Cunming Lv
Shuhui Zheng
In the field of diabetic ulcer treatment, plant-derived pure small molecular compounds loaded in hydrogels have shown significant potential value and importance. However, existing literature on hydrogel dressings for the treatment of diabet...