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Localized and sustained release of Puerarin from a calcium phosphate hydrogel enhances immunomodulatory bone repair by modulating pro-healing macrophage phenotype transitions

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Manipulating the immune microenvironment is crucial for bone repair, with macrophages serving as key regulators. Their polarization state significantly influences bone healing. In this study, we examined the immunoregulatory effects of Puerarin, particularly i... ...