Integrated computational, pharmacological and molecular investigations of piperitone in mitigating Alzheimer disease pathology by targeting cholinesterases, β-secretase and neuroinflammation [0.03%]
计算、药理和分子综合研究 pepparitone 通过靶向胆碱酯酶、β-分泌酶和神经炎症来缓解阿尔茨海默病病理学
Rubia Anwer,Ihsan Ullah,Arif-Ullah Khan et al.
Rubia Anwer et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder linked with oxidative imbalance, cholinergic dysfunction and neuroinflammation, necessitates developing new multitarget natural compounds with potential disease-modifying ...
Atraric acid mitigates the cognitive and pathological deficits in mice via Aβ1-42 induced Alzheimer's disease [0.03%]
atraric酸通过Aβ1-42诱导的阿尔茨海默病缓解认知和病理缺陷
Waqar Ali,Kyonghwan Choe,Talha Nasir et al.
Waqar Ali et al.
Ethanolic extract of propolis attenuates inflammation and promotes mucosal repair in an indomethacin-induced murine model of enteropathy [0.03%]
乙醇提取的蜂胶通过减轻炎症和促进肠粘膜修复来改善吲哚美辛致小鼠肠病模型的作用研究
Oussama Medjeber,Hayet Rafa,Kahina Touri et al.
Oussama Medjeber et al.
Fecal microbiota transplantation in inflammatory bowel disease: a systematic review and meta-analysis of randomized controlled trials (2020-2025) [0.03%]
炎症性肠病中粪菌移植的系统评价和meta分析(2020-2025)
Sania Ikram,Muneeb Ullah,Juho Lee et al.
Sania Ikram et al.
Background: Fecal microbiota transplantation (FMT) has emerged as a therapeutic strategy for Inflammatory Bowel Disease (IBD) including ulcerative colitis (UC) and Crohn's disease (CD). Although multiple randomized contro...
Anti-inflammatory effects of Myrtus communis L. (myrtle): experimental and clinical evidence with an immunological perspective [0.03%]
Myrtus communis L. (Myrtle)的抗炎作用:实验和临床证据及其免疫学意义
Ilhan Tahrali
Ilhan Tahrali
Myrtus communis L. (myrtle) is a medicinal plant widely used in traditional medicine. Due to the broad range of therapeutic applications of its leaves, fruits, and flowers, it has gained increasing scientific attention particularly in recen...
Phytochemicals from Fagonia glutinosa with anti-hemorrhoid, antipyretic, antiarthritic, antimicrobial and antioxidant activities [0.03%]
具有抗痔疮、解热、抗关节炎、抗菌和抗氧化活性的Fagonia glutinosa植物化学物质
Rima Benderradji,Naima Benkiki,Amel Hamdi et al.
Rima Benderradji et al.
Fagonia glutinosa has been traditionally used by Saharan populations in Algeria for its therapeutic properties. The present investigation was designed to identify the plant's bioactive constituents and to evaluate its in vitro antioxidant, ...
Trientine ameliorates bleomycin-induced pulmonary fibrosis in rats through copper chelation and modulation of the CTR1/LOX/COL pathway [0.03%]
三价铁螯合剂屈rena改善博来霉素诱导的大鼠肺纤维化:通过铜螯合和调节CTR1 / LOX / COL通路发挥作用
Ibrahim T Khalil,Mahmoud Elshal,Norhan M Elsayed et al.
Ibrahim T Khalil et al.
Pulmonary fibrosis (PF) remains a devastating disease. Copper (Cu), an essential trace element, has been implicated in fibrotic processes in various organs, including the lungs. This study investigated the potential protective effects of tr...
Hydroxytyrosol-encapsulated solid lipid nanoparticles mitigate induced arthritis via modulating the cytokines and MMP-13 expression and downregulating oxidative stress in rats [0.03%]
茋溶脂纳米粒通过调节细胞因子和基质金属蛋白酶-13的表达及下调氧化应激诱导的大鼠关节炎模型中的氧化反应
Noor Ul Huda,Aftab Ahmad,Muhammad Anjum Zia et al.
Noor Ul Huda et al.
Therapeutic efficacy of Curcuma longa leaf extract in experimental models of arthritis [0.03%]
姜黄叶提取物治疗关节炎的疗效研究
Eleazar Chukwuemeka Anorue,Vincent Eric Okechukwu Ozougwu,Amaechi L Ogara et al.
Eleazar Chukwuemeka Anorue et al.
Arthritis is a chronic inflammatory disorder that affects millions worldwide, leading to persistent joint pain, stiffness, swelling, and impaired mobility. Although conventional therapies are effective in symptom management, their long-term...
The dual role of lipoteichoic acid: from immune modulation to therapeutic applications in disease treatment [0.03%]
脂壁酸的双重作用:从免疫调节到疾病治疗中的潜在应用
Mingcong Ding,Zhenshan Wang,Linyu Xu et al.
Mingcong Ding et al.