Valorization of 2-aminoethoxydiphenyl borate as a neurotherapeutic agent: modulation of calcineurin, TRPC1 and MARK2/GSK-3β signaling in scopolamine-triggered tauopathy [0.03%]
2-氨基乙氧基二苯基硼酸作为神经治疗剂的价值：在东莨菪碱触发的tau蛋白病中调节钙调磷酸酶、TRPC1和MARK2/GSK-3β信号通路
Akash Kewal,Mithun Singh Rajput,Jigna Shah et al.
Akash Kewal et al.
In Alzheimer's disease (AD), amyloid beta (Aβ) plaques and hyperphosphorylated tau tangles drive neurodegeneration and cognitive decline. Disrupted calcium homeostasis-particularly via transient receptor potential canonical-1 (TRPC1) chann...
Atriplex portulacoides L. derived phytochemicals mitigate acetic acid induced colitis in rats via orchestrating Nrf2/Keap1 signalling and LncRNAs gene expression [0.03%]
通过调控Nrf2/Keap1信号传导和长链非编码RNA基因表达 荠菜素减轻大鼠乙酸诱发的结肠炎
Maha Hassan,Marwa M Mona,Marwa M Abd-Elsalam et al.
Maha Hassan et al.
Background: This study is the first to elucidate the mechanistic actions of Atriplex portulacoides L. methanolic extract (APME) as a natural treatment of acetic acid-induced ulcerative colitis on rat model. ...
Correction to: Anti-inflammatory potential of Piper betleoides C. DC., a promising piper species of North East India: in vitro and in vivo evidence and mechanistic insight [0.03%]
correction to:北印度东北部一种有前景的胡椒属植物Piper betleoides C. DC.的抗炎潜力：体外和体内证据及机制分析
Rikraj Loying,Bhaben Sharmah,Hiranmoy Barman et al.
Rikraj Loying et al.
Published Erratum
Inflammopharmacology. 2026 Jul 29. DOI:10.1007/s10787-026-02352-w 2026
Arbutin mediated neuroprotection in zebrafish model of traumatic brain injury via modulating Nrf2/NF-κB pathway [0.03%]
熊果素通过调节Nrf2/NF-κB途径介导的脑创伤损伤斑马鱼模型中的神经保护作用
Shamsher Singh
Shamsher Singh
Traumatic Brain Injury (TBI) is a major cause of mortality and disability worldwide and is associated with oxidative stress, neuroinflammation, and neurotransmitter imbalance. Arbutin, a naturally occurring glycoside with known antioxidant ...
Rutin as a multi-target anti-inflammatory phytochemical in arthritic disorders: pharmacological mechanisms and therapeutic potential [0.03%]
芦丁作为抗炎类植物化学物治疗关节炎的多种作用机制和治疗潜力
Muhammad Muzammil Nazir,Asma Ashraf
Muhammad Muzammil Nazir
Rutin, a bioactive flavonoid widely present in medicinal plants such as Fagopyrum esculentum, Ruta graveolens, and citrus species, has been traditionally used for inflammatory conditions, including joint disorders. Despite its long-standing...
Immunometabolic reprogramming in multiple sclerosis: from pathogenic amplifier to therapeutic target in neuroinflammation and remyelination [0.03%]
免疫代谢重新编程在多发性硬化症中的作用：从神经炎症和少突胶质细胞反应的放大器到治疗靶点
Ghada A Badawi,Rehab M El-Sayed,Mohamed N Fawzy
Ghada A Badawi
Multiple sclerosis (MS) has conventionally been considered a prototypical autoimmune disorder. While modern immunotherapies effectively control relapsing conditions, they fail to avert progressive neuroinflammation, neurodegeneration, and r...
Transient receptor potential vanilloid channels in inflammatory bowel diseases: linking inflammation, angiogenesis, and oxidative stress [0.03%]
瞬时受体电位香草酸通道在炎症性肠病中的作用：连接炎症、血管生成和氧化应激
Peihong Li,Yikun Zhang,Siqing Guo et al.
Peihong Li et al.
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is characterized by chronic relapsing intestinal inflammation driven by complex interactions among immune dysregulation, epithelial barrier disrup...
Clove oil in combination with flurbiprofen attenuated imiquimod-induced psoriasis-like skin inflammation in a mouse model: A mechanistic study [0.03%]
丁香油联合氟比洛芬对小鼠咪喹莫德诱导的银屑病样皮肤炎症的改善作用及机制研究
Qianqian Xing,Shuaijie Wang,Hafiz Muhammad Zubair et al.
Qianqian Xing et al.
Psoriasis is an immune-mediated chronic inflammatory skin disease characterized by scaly plaques, erythema, and thick skin. Psoriasis management is complicated and multifaceted as this disease is linked to serious systemic consequences like...
Imeglimin confers protection against intestinal ischemia/reperfusion injury in rats through AMPK-dependent inhibition of NF-κB/NLRP3 inflammasome signaling and mitigation of oxidative stress and apoptosis [0.03%]
依美格利明通过AMPK依赖性抑制NF-κB/NLRP3炎性小体信号及抗氧化应激和凋亡缓解大鼠肠道缺血/再灌注损伤
Walaa Yehia Abdelzaher,Hanaa Mohamed Khalaf,Rabeh Khairy Saleh et al.
Walaa Yehia Abdelzaher et al.
Background and aim: Intestinal ischemia/reperfusion (I/R) injury is a critical condition characterized by oxidative stress, inflammation, and apoptosis, leading to significant tissue damage. Imeglimin (IMEG), a novel anti...
Anti-inflammatory evaluation of HPLC-GC quantified phytochemicals from Acalypha indica L. using LPS-induced inflammation model [0.03%]
基于LPS诱导的炎症模型量化Acalypha indica L.化学成分的抗炎评价
Divya Sharma,Mahaveer Dhobi
Divya Sharma
Background: Inflammation is a crucial host defense mechanism; however, its prolonged activation contributes to the pathogenesis of respiratory infections. Acalypha indica L. (Haritamanjari), widely used in South Asia, has...