Pharmaco-therapeutic modulation of the Glo1-Nrf2-RAGE functional network in chronic inflammation: polyphenols in the context of current anti-inflammatory therapy [0.03%]
慢性炎症中的药理学调制：Glo1-Nrf2-RAGE功能网络的多酚类抗炎疗法背景下的作用机制研究
Sajid Ali,Muhammad Saeed Akhtar,Adnan Amin et al.
Sajid Ali et al.
Chronic inflammation is a central driver of numerous disorders, including metabolic, cardiovascular, neurodegenerative, autoimmune, and malignant diseases. Although current anti-inflammatory pharmaco-therapeutic strategies, including nonste...
Combatting psoriasis with nanomedicine: gamma-amino butyric acid-chitosan nanoparticles as a targeted anti-psoriatic therapy [0.03%]
用纳米药物治疗银屑病：γ-氨基丁酸壳聚糖纳米颗粒作为靶向抗银屑病疗法
Dina Ibrahim,Alyaa Farid,Mohamed Kishta et al.
Dina Ibrahim et al.
The chronic inflammation and oxidative stress are the most deleterious pathogenic factors of psoriasis (PS). While gamma-aminobutyric acid (GABA) possesses well-documented immunomodulatory and antioxidant properties, its therapeutic potenti...
Medicinal plants as alternative and adjunct antimicrobial agents in ear, nose, and throat (ENT) Infections [0.03%]
药用植物作为耳鼻喉感染的替代及辅助抗菌剂
Serpil Demirci Kayıran,Talih Özdaş,Umay Merve Güven Bölgen et al.
Serpil Demirci Kayıran et al.
Medicinal plants are widely used worldwide for ear, nose, and throat (ENT) disorders and have a long history of traditional application. This review aims to summarize current experimental and clinical evidence on medicinal plants used for E...
Boswellia serrata dry extract with intestinal anti-inflammatory properties also accelerates gastric ulcer healing in rats [0.03%]
具有肠道抗炎作用的乳香提取物也可加速大鼠胃溃疡的愈合
Franco Giovanni Sandri Serafim,Lucas Fontana Breguez da Cunha,Larissa Venzon et al.
Franco Giovanni Sandri Serafim et al.
Boswellia serrata is a medicinal plant traditionally used to treat inflammatory conditions and this study aimed to evaluate the efficacy of B. serrata dry extract (BSDE) in treating gastric ulcers and ulcerative colitis. Chronic gastric ulc...
Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway [0.03%]
网络药理学和体内实验分析验证石榴叶对皮肤硬皮病抗纤维化潜力：氧化应激、炎症和TGF-β1/Snail 1/p-Smad 3信号通路的作用
Sara M Baraka,Zeinab A El-Gendy,Eman A W El-Abd et al.
Sara M Baraka et al.
Given the significant efficacy of the Punica granatum in enhancing skin health, this research employed network pharmacology and in vivo studies to explore the P. granatum ethanolic leaf extract's (PGEL) mechanism in alleviating skin scleros...
Metformin for knee osteoarthritis in overweight and obese adults: a systematic review and meta-analysis of efficacy, safety, and disease-modifying anti-inflammatory potential [0.03%]
二甲双胍治疗成人膝骨关节炎的疗效、安全性及抗炎潜力的系统评价和meta分析
Santenna Chenchula,Krishna Chaitanya Amerneni,R Padmavathi et al.
Santenna Chenchula et al.
Introduction: Knee osteoarthritis (OA) is a degenerative joint disease involving progressive cartilage loss, subchondral bone remodelling, and inflammation. This systematic review and meta-analysis aimed to assess the eff...
Chitosan-curcumin nanoparticles: a potential nano-therapeutic for cognitive restoration in a streptozotocin-induced rat model of Alzheimer's disease [0.03%]
壳聚糖-姜黄素纳米粒子：阿尔茨海默病大鼠模型认知恢复的潜在纳米药物治疗剂
Mohadeseh Shiravi Khozani,Mohammadreza Palizvan,Ghasem Mosayebi et al.
Mohadeseh Shiravi Khozani et al.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory impairment, with no definitive cure currently available. Neuroinflammation, oxidative stress, ...
Amelioration of experimentally induced-arthritis by guaiazulene through targeting inflammatory and oxidative stress biomarkers in Wistar rat [0.03%]
金合欢烃通过靶向大鼠炎症和氧化应激生物标志物实验性诱导的关节炎的改善
Ammara Saleem,Arooj Fatima,Muhammad Furqan Akhtar
Ammara Saleem
Rheumatoid arthritis (RA), a systemic autoimmune disease, is related with the symmetrical synovitis of the joints which causes joint pain. The intake of anti-rheumatic drugs can lead to several adverse effects. Phytochemicals are effective ...
Aqueous extract of Psidium glaziovianum Kiaersk leaves acts on muscarinic and opioid receptors and reduces cytokines and inflammatory infiltrates in vivo models [0.03%]
巴西雅乐果叶提取物通过作用于胆碱能受体和阿片受体减少体内模型的细胞因子和炎症浸润
Wêndeo Kennedy Costa,Paulo Henrique Eloi Fernandes,Paloma Maria da Silva et al.
Wêndeo Kennedy Costa et al.
The anti‑inflammatory activity of 2‑iminothiazolidines: the role of PPARγ and M2 macrophage subpopulations [0.03%]
2-亚氨基硫唑烷的抗炎活性：PPARγ和M2型巨噬细胞亚群的作用
Eduarda Talita Bramorski Mohr,Tainá Larissa Lubschinski,Pedro Augusto Marocco Moro et al.
Eduarda Talita Bramorski Mohr et al.
Thiazolidine derivatives exert anti-inflammatory effects by inhibiting the NF-κB pathway and promoting macrophage polarization toward the anti-inflammatory M2 phenotype, partially through PPARγ activation. Our previous work identified thi...