Sohome Das,Anuradha Mishra,Narahari Narayan Palei
Sohome Das
Targeting NF-κB and JAK/STAT pathways in rheumatoid arthritis: emerging nanocarrier-based drug delivery approaches [0.03%]
靶向NF-κB和JAK/STAT通路治疗类风湿关节炎：基于纳米载体的药物递送新方法
G Surendra,Jeetendra Kumar Gupta,E Susithra et al.
G Surendra et al.
Opioidergic and GABAergic mechanisms underlie the anti-nociceptive effects of adamantane amino thiazole derivatives: synthesis, toxicity evaluation and mechanistic insights using standard pre-clinical models [0.03%]
阿片类和GABA机制影响adamantane氨基噻唑衍生物的镇痛作用：合成，毒性评估及标准临床前模型下的机理研究
Urooj Aman,Gowhar Ali,Atteeque Ahmed et al.
Urooj Aman et al.
The present study involves the synthesis, toxicity assessment and investigation of anti-nociceptive potential of two adamantane amino thiazole derivatives (AATD), including [N-((1s, 3s)-adamantan-1-yl)-4-(4-bromophenyl)thiazol-2-amine] (AAT...
Zingiber officinale essential oil mitigates psoriasis-like skin inflammation by modulating inflammatory and proliferative responses: in-silico, in-vitro, and in-vivo studies [0.03%]
姜黄油缓解银屑病样皮肤炎症：基于计算机模拟、体外和体内研究结果显示其可调节炎性及增殖反应
Vipin Kumar Singh,Debasish Sahoo,Kirti Agrahari et al.
Vipin Kumar Singh et al.
Psoriasis, a chronic skin disease characterized as keratinocytes hyperproliferation and inflammation, remains a clinical challenge due to limitations of long-term synthetic drug therapy. Plant drugs can meet this limitation therefore, in th...
Usnic acid attenuates inflammation and joint damage in Freund's complete adjuvant-induced arthritis in rats [0.03%]
乌术酸对完全弗氏佐剂诱导的大鼠类风湿关节炎的抗炎和保护软骨作用研究
Ammara Razaq,Ambreen Ishaque,Muhammad Nadeem Alvi et al.
Ammara Razaq et al.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation, progressive joint destruction, and functional disability. Usnic acid (UA), a lichen‑derived secondary metabolite, has shown anti‑...
Astrocytic dysfunction in Parkinson's disease pathogenesis: focusing on alpha-synuclein [0.03%]
帕金森病发病机制中星形胶质细胞功能障碍：聚焦α-突触核蛋白
Zainah Al-Qahtani,Hayder M Al-Kuraishy,Ali I Al-Gareeb et al.
Zainah Al-Qahtani et al.
Topoisomerase I/II inhibitors: from established drugs to next-generation therapeutics [0.03%]
拓扑异构酶I/II抑制剂：从传统药物到下一代治疗药
Pinky Arora,Ashi Sharma,Shivank Sharma et al.
Pinky Arora et al.
Topoisomerases are crucial enzymes that control the DNA topology in replication, transcription, recombination, and chromosomal segregation, and therefore are validated as the targets of anticancer therapy. Topoisomerase-targeting agents are...
Nanoparticle embedded dot matrix transdermal patches: a novel approach for targeted and controlled drug delivery in rheumatoid arthritis [0.03%]
嵌入纳米颗粒的点矩阵透皮贴片：类风湿性关节炎药物靶向和控制释放的新方法
Devanshu,Alok Raj,Rahul Pratap Singh et al.
Devanshu et al.
Background: RA is a chronic autoimmune disease characterized by synovial inflammation, cartilage destruction, and ultimately bone erosion that affects approximately 0.5-1% of the global population, with significant disabi...
α-Pinene alleviates inflammatory responses and oxidative stress in freund's complete adjuvant induced arthritic rat model and associated risk factors of atherosclerosis [0.03%]
α-蒎烯对完全弗氏佐剂诱导的类风湿关节炎大鼠模型炎症反应和动脉粥样硬化相关危险因素的影响作用研究
Khadija Ali,Iqral,Ali Sharif et al.
Khadija Ali et al.
Arthritis is characterized by joint inflammation that can lead to severe bone erosions and affects 0.1 to 2.0% of people globally. People with RA are 1.5 times more likely to develop CVDs including atherosclerosis. The goal of the current i...
Multi-target modulation of inflammatory pathways by Colchicum luteum in rheumatoid arthritis through experimental and in silico evidence [0.03%]
通过实验和计算证据证明秋水仙在类风湿关节炎中可通过多靶点调节炎症通路
Iqra Farzeen,Salma Sultana,Sana Inam et al.
Iqra Farzeen et al.