MicroRNA-mediated regulation of inflammatory gene expression in asthma [0.03%]
哮喘中microRNA对炎症基因表达的调控作用
Tinku Gupta,Reena Badhwar,Madhuri Grover et al.
Tinku Gupta et al.
Asthma is a long-term inflammatory condition of the airways that includes complex immune dysregulation, epithelial barrier issues, and structural remodelling. The critical function of the miRNAs as modulators of inflammatory gene expression...
Anti-acne cinnamic acid bigel: a hybrid topical system for concurrent modulation of inflammation and microbial load [0.03%]
抗痤疮肉桂酸bigel制剂：一种兼具抗炎和抗菌作用的外用系统
Jitendra W Gajbe,Ashwini R Madgulkar,Minakshi B Shinde et al.
Jitendra W Gajbe et al.
Background: Acne vulgaris is a chronic inflammatory skin disease aggravated by Cutibacterium acnes (P. acnes). Conventional drug delivery treatments researchers reported irritation, resistance and poor efficacy. Poor skin...
Himalayan medicinal plants for gastrointestinal disorders: ethnopharmacology and mechanistic insights [0.03%]
喜马拉雅地区治疗胃肠疾病的药用植物：民族药理学和机制研究
Anil Punetha,Abhay Chaturvedi,Aparna Bahuguna et al.
Anil Punetha et al.
The Himalayan region has a rich and diverse flora specially of medicinal plants, many of which are traditionally used to treat various gastrointestinal (GI) disorders. GI disorders significantly contribute to global morbidity and mortality,...
Decoding neuroinflammation: the critical role of NLRP3 inflammasome in Alzheimer's disease [0.03%]
解码神经炎症：NLRP3炎性小体在阿尔茨海默病中的关键作用
Bharat Chaudhary,Sneha Kumari,Prajjwal Sharma et al.
Bharat Chaudhary et al.
The hallmarks of Alzheimer's disease (AD), a progressive neurodegenerative disease, include tau tangles, amyloid-β (Aβ) plaques, cognitive impairment, and severe neuroinflammation. A key molecular mediator linking immunological activation...
Split vs. single-dose oral methotrexate in rheumatoid arthritis: a meta-analysis of randomized controlled trial [0.03%]
甲氨蝶呤治疗类风湿性关节炎的分裂法与单剂量法的系统评价和元分析研究
Gabriela Stutz F Moreira,Lucas M Barbosa
Gabriela Stutz F Moreira
Anti-inflammatory potential of the CISACN adduct in LPS-induced murine models [0.03%]
CISACN加合物在脂多糖诱导的小鼠模型中的抗炎潜力研究
Louise M de Lima,Francisco A A F Gadelha,Laércia K D Paiva Ferreira et al.
Louise M de Lima et al.
Acute lung injury (ALI) is characterized by a severe inflammatory response that triggers pulmonary edema, reduced lung compliance, and hypoxemic respiratory failure. To date, there is no effective standard pharmacotherapy for this condition...
Bioactive compounds for neuroinflammation and neuropathic pain management: molecular and cellular mechanisms [0.03%]
神经炎症和神经病理性疼痛管理的生物活性化合物：分子和细胞机制
Iftakhar Ahmad,Sachin Kothawade,Tasmia Jahin Mim et al.
Iftakhar Ahmad et al.
Bioactive compounds are a promising multi-target strategy for managing neuroinflammation and chronic pain. Bioactive compounds such as Paeonol, Kaempferol, and Acteoside demonstrate significant analgesic and anti-inflammatory effects by inh...
Metformin repurposing in gout: enhancing febuxostat efficacy through anti-inflammatory and metabolic modulation: a randomized controlled double-blind study [0.03%]
二甲双胍在痛风再利用中的作用：通过抗炎和代谢调节增强非布司他的疗效：一项随机、双盲试验
Dalia N Abdel-Sadek,Tarek M Abd-Elazez,Sahar M El-Haggar
Dalia N Abdel-Sadek
Background: Gout is a chronic inflammatory disorder characterized by recurrent painful flares and elevated uric acid levels. Metformin possesses anti-inflammatory and metabolic regulatory properties that may offer additio...
Kaempferol-loaded solid lipid nanoparticles attenuate cartilage degradation and inflammation by modulating the expression of pro and inflammatory cytokines, MMP-13 and oxidative stress markers in adjuvant induced arthritic rats [0.03%]
芸香苷载固体脂质纳米粒通过调节促炎细胞因子、MMP-13及氧化应激标记物的表达抑制弗氏完全佐剂诱导的大鼠关节软骨降解及炎症反应
Anam Niamat,Aftab Ahmad,Nayla Munawar et al.
Anam Niamat et al.
Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with inflammation, oxidative stress, and progressive joint damage. Although kaempferol exhibits strong anti-inflammatory and antioxidant activities, its therapeutic applic...
2-Butanone 4-glucopyranoside 6'-O-gallate isolated from Memecylon scutellatum exhibits anti-inflammatory activity via modulation of the NF-κB and MAPK signaling pathways in LPS-stimulated RAW 264.7 macrophages [0.03%]
Memecylon scutellatum中分离的2-丁酮-4-D-葡萄吡喃糖苷-6'-O-棓酸通过调节LPS刺激RAW 264.7巨噬细胞中的NF-κB和MAPK信号通路表现出抗炎活性
Duong Thu Trang,Tran Thi Thu Phuong,Hai Pham-The et al.
Duong Thu Trang et al.
Inflammation is a major contributor to the development of chronic diseases, including diabetes, rheumatoid arthritis, and cancer. The Memecylon genus has been demonstrated for its diverse biological activities such as antioxidant, antidiabe...