The anti‑inflammatory activity of 2‑iminothiazolidines: the role of PPARγ and M2 macrophage subpopulations [0.03%]
Eduarda Talita Bramorski Mohr,Tainá Larissa Lubschinski,Pedro Augusto Marocco Moro et al.
Eduarda Talita Bramorski Mohr et al.
Thiazolidine derivatives exert anti-inflammatory effects by inhibiting the NF-κB pathway and promoting macrophage polarization toward the anti-inflammatory M2 phenotype, partially through PPARγ activation. Our previous work identified thi...
Anti-inflammatory role of metal and metal oxide nanoparticles: a review of toxicity, green synthesis, and immunomodulatory mechanisms [0.03%]
Rimsha Ashraf,Shaukat Ali,Muhammad Summer et al.
Rimsha Ashraf et al.
Metallic nanoparticles (MNPs) have emerged as promising agents for drug delivery and therapeutic applications due to their unique physicochemical properties. However, their widespread use is limited by intrinsic toxicity arising from their ...
Protective effects of antidepressants against ulcerogenic agents: insights from nonclinical studies [0.03%]
Caroline Stringari,Heloisa Stringari,Thiago Farias de Queiroz E Silva et al.
Caroline Stringari et al.
LincRNA-Cox2 at the crossroads of innate immunity and inflammation: mechanisms, disease associations, and therapeutic perspectives [0.03%]
Yinxing Sheng,Haopeng Jiang,Xueyan Liu et al.
Yinxing Sheng et al.
Integration of phytochemical profiling and pharmacological assessment of Eucalyptus salubris seeds: a promising natural anti-inflammatory agent [0.03%]
Nouha Ferjani,Reham Hassan Mekky,María Del Mar Contreras et al.
Nouha Ferjani et al.
In this work, Eucalyptus salubris seeds extract (ESS) was characterized using liquid chromatography (LC) coupled to mass spectrometry (MS), and its in vitro and in vivo anti-inflammatory properties were evaluated. Through LC-MS and MS2 anal...
Clinical efficacy and mechanisms of krill oil supplementation in knee osteoarthritis: meta-analysis and mechanistic insights [0.03%]
磷虾油补充对膝骨关节炎的临床疗效及机制：meta分析与机制见解
Haiyang Kou,Huaiquan Liu,Lingyan Lai et al.
Haiyang Kou et al.
Objective: To evaluate the clinical efficacy and safety of krill oil supplementation in patients with knee osteoarthritis (KOA) through a systematic review and meta-analysis. Potential mechanisms are discussed based on ex...
Quercetin-loaded exosomes derived from human umbilical cord mesenchymal stem cells alleviate microglia-mediated neuroinflammation via an anti-inflammatory mechanism [0.03%]
人脐带间充质干细胞来源的檞皮素负载外泌体通过抗炎机制缓解小胶质细胞介导的神经炎症
Sajeda Osman,Gulen Melike Demirbolat,Sevim Isik
Sajeda Osman
Neuroinflammation is central to the progression of neurodegenerative diseases (NDs), with microglia contributing through the release of pro-inflammatory and oxidative mediators. Although quercetin (Que) possesses potent anti-inflammatory an...
Anti-neuroinflammatory and neuroprotective effects of acteoside (verbascoside) in experimental models of neurodegeneration: a systematic review and meta-analysis [0.03%]
胡薄荷苷(动情素苷)在神经退行性病变实验模型中的抗神经炎症和神经营养作用：系统评价和meta分析研究
Sudatt Dixit,Gollapalle Lakshminarayanashastry Viswanatha,Yogendra Nayak
Sudatt Dixit
Safety and efficacy of COVID-19 vaccines in pregnant and lactating women: a comprehensive review [0.03%]
新型冠状病毒疫苗在孕产妇中的安全性和有效性：全面回顾
Sumel Ashique,Mohini Mondal,Md Sadique Hussain et al.
Sumel Ashique et al.
Breastfeeding plays a critical role in providing essential nutrients and antibodies that enhance the health of new-borns and infants, supporting their immune systems and overall growth and development. Healthcare professionals, universally ...
Plant-derived indole alkaloids in chronic inflammatory diseases: molecular mechanisms, therapeutic potential and translational challenges [0.03%]
植物来源的吲哚生物碱在慢性炎症性疾病中的作用：分子机制、治疗潜力和转化挑战
Manas Jyoti Kapil,Mrinmoy Basak,Koushik Nandan Dutta et al.
Manas Jyoti Kapil et al.
Background: Chronic inflammatory diseases are major global health challenges driven by persistent oxidative stress and dysregulated immune signalling. Plant-derived indole alkaloids are structurally diverse metabolites fo...