Ruxuan Li,Yulan Song,Shi Peng et al.
Ruxuan Li et al.
Pyroptosis, a form of programmed cell death characterized by inflammation, plays a significant role in the pathogenesis of lung injury. This review explores the intricate relationship between pyroptosis and lung injury, emphasizing the crit...
Dapagliflozin ameliorates Alzheimer's disease in rats via stimulating the protective arm of renin angiotensin system and suppressing neuroinflammation [0.03%]
达格列净通过刺激肾素血管紧张素系统的保护作用并抑制神经炎症来改善大鼠阿尔茨海默病
Zeinab M Awwad
Zeinab M Awwad
Alzheimer's disease (AD) is associated with renin angiotensin system (RAS) overactivation that stimulates amyloid β-induced neurodegeneration. Activation of angiotensin II type 1 (AT1) receptor impairs the protective phosphoinositide 3-kin...
Gold nanoparticles (AuNPs) as emerging anti-inflammatory agents: mechanisms, therapeutic advances, and future directions-a systematic review and meta-analysis [0.03%]
金纳米颗粒(AuNPs)作为新兴的抗炎剂：机制、治疗进展和未来方向-系统评价和荟萃分析
Shaziya Khan,Suraj N Mali,João Marcos Carvalho-Silva et al.
Shaziya Khan et al.
Inflammation contributes significantly to the development of several chronic disorders, including rheumatoid arthritis, psoriasis, cardiovascular diseases, and neurodegenerative disorders. Although conventional anti-inflammatory medications...
Therapeutic and research frontiers in fibromyalgia: integrating pathophysiology with innovative drug repurposing [0.03%]
纤维肌痛的治疗和研究前沿：整合发病机制与创新药物再定位
Sheer A Joodi,Dalia A Nawwar,Nora O Abdel Rasheed et al.
Sheer A Joodi et al.
Fibromyalgia (FM) is a complex chronic pain syndrome characterized by widespread musculoskeletal pain, fatigue, sleep disturbance, psychological symptoms, and cognitive dysfunction, profoundly impairing quality of life. Despite its multifac...
The effect of pregabalin on pain and function in knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials [0.03%]
普瑞巴林对膝骨关节炎镇痛和功能影响的系统评价和meta分析
Chia Siang Kow,Dinesh Sangarran Ramachandram,Kaeshaelya Thiruchelvam
Chia Siang Kow
Background: Knee osteoarthritis (OA) is a prevalent chronic condition characterized by joint pain and functional impairment. While non-steroidal anti-inflammatory drugs (NSAIDs) remain the cornerstone of pharmacologic man...
Natural products targeting cytokine-regulated SASP inflammation networks in Ovarian cancer: Implications on immune escape and molecular resistance [0.03%]
针对卵巢癌细胞焦亡炎症网络的天然药物：对免疫逃逸和分子耐药性的启示
Benedict Mathews Paul,Gowtham Kannan,Arunachalam Karuppasamy et al.
Benedict Mathews Paul et al.
Ovarian cancer (OC) is one of the most lethal gynecological malignancies, with incidence and mortality rates increasing markedly among women aged 65 years and older. Aging-associated biological alterations, including genomic instability, te...
Synergistic synbiotic therapies for ulcerative colitis: mechanistic insights from multi-targeted pathways in animal models [0.03%]
益生元联合疗法治疗溃疡性结肠炎：动物模型中多靶点途径的机制见解
Hassabelrasoul O Awad,Mihad Omer,Omer I Omer et al.
Hassabelrasoul O Awad et al.
Ulcerative colitis (UC) is a chronic inflammatory bowel disease whose complex etiology is increasingly linked to gut microbiota dysbiosis. While conventional pharmacological treatments often face limitations due to side effects, cost, and v...
Phytotherapeutic potential of Gossypium barbadense L. root as an alternative therapy for colitis: a comprehensive review with network pharmacology insights [0.03%]
雷蒙棉根的植物药治疗潜力作为治疗结肠炎的替代疗法：结合网络药理学见解的全面综述
Amna Abou Bakr,Walaa K Elabd,Said S Moselhy et al.
Amna Abou Bakr et al.
Inflammatory bowel disease (IBD), particularly ulcerative colitis (UC), remains a major global health challenge characterized by chronic, relapsing inflammation of the colonic mucosa. Although conventional pharmacotherapies, including corti...
Nanomedicine targeting neuroinflammatory pathways in Alzheimer's disease: a new frontier in inflammopharmacology [0.03%]
针对阿尔茨海默病神经炎症途径的纳米医学：炎性药理学的新前沿
Sumit Kaushik,Jamal E Fatima,Amatul Raheem et al.
Sumit Kaushik et al.
Alzheimer's disease (AD) is a multifactorial neurodegenerative illness characterized by progressive cognitive impairment, synaptic compromise, and relentless neuroinflammation. Increasing evidence suggests that neuroinflammatory cascades or...
Mangiferin in combination with primaquine reduces disease progression and transmission potential while alleviating cerebral pathology through suppression of neural cell apoptosis in experimental cerebral malaria [0.03%]
芒果苷联合氯喹通过抑制神经元细胞凋亡来减少疾病进展和传播潜能并缓解实验性脑疟疾的脑病理学变化
Subham Halder,Saikat Mukherjee,Soubhik Ghosh et al.
Subham Halder et al.
Despite the availability of effective antimalarial drugs, cerebral malaria (CM) remains one of the deadliest manifestations of malaria and is associated with high mortality and severe neurological sequelae. The World Health Organization (WH...