Targeted delivery of curcumin based on nanocarriers: potential therapeutic strategies for noninfectious arthritis [0.03%]
基于纳米载体的姜黄素靶向递送：非感染性关节炎潜在治疗策略
Baihui Cai,Yiting Cai,Han Wang et al.
Baihui Cai et al.
Arthritis, an acute inflammatory disease affecting single or multiple joints, causes irreversible damage to cartilage and bone, leading to substantial pain and economic burden. Current treatments lack specificity. Curcumin, with its anti-in...
A novel oral interleukin-23 receptor antagonist peptide, icotrokinra, for moderate-to- severe plaque psoriasis: a systematic review and meta-analysis of randomized controlled trials [0.03%]
一种针对中重度斑块状银屑病的新型口服白细胞介素23受体拮抗肽icotilumod：系统评价和Meta分析
Martin Cevallos-Cueva,Chinenye Onejeme,Laura Ghanem et al.
Martin Cevallos-Cueva et al.
Background: Icotrokinra represents a novel therapeutic approach that may address limitations associated with current injectable biologic therapies, including storage requirements and self-administration complexity, and ma...
Ulcerative colitis, pathophysiological mechanisms and drug repurposing: a new therapeutic dawn-narrative review [0.03%]
溃疡性结肠炎的发病机制及老药新用：新的治疗曙光——叙述性综述
Mostafa M Bahaa,Mahmoud S Abdallah,Esraa M Mosalam et al.
Mostafa M Bahaa et al.
Crohn's disease and ulcerative colitis (UC) are among the intestinal conditions that make up the category known as inflammatory bowel disease. Globally, UC prevalence and incidence are currently rising. There was substantial evidence that m...
Essential oil from Eugenia stipitata McVaugh leaves exhibits antinociceptive effect via opioid receptor activation [0.03%]
activate opioid受体实现抗痛觉作用
Wêndeo Kennedy Costa,Priscilla Glazielly Dos Santos de Moraes,João Guilherme Euzebio Souza et al.
Wêndeo Kennedy Costa et al.
Eugenia stipitata McVaugh, a species of the Myrtaceae family, is widely distributed in tropical regions and has traditionally been used by local communities to treat mouth and throat inflammation, stomach pain, wounds, fever, diarrhea, and ...
Comparative efficacy of transdermal buprenorphine versus diclofenac in the management of knee osteoarthritis: a randomized controlled trial with network pharmacology insights [0.03%]
经皮给药丁丙诺啡与(diclofenac)治疗膝关节骨关节炎的疗效比较：随机对照试验及网络药理学视角解读
Abhay Singh,Sneha Yadav,Anil Kumar Gulia et al.
Abhay Singh et al.
Background: Osteoarthritis (OA) is a degenerative joint disease, which is accompanied by chronic pain and functional impairment, especially among the elderly population. Transdermal drug delivery offers a non-invasive opt...
Effects of Pelargonium sidoides root extract on paw oedema, nitric oxide signaling, and synovial vascular changes in a rat model of adjuvant-induced arthritis [0.03%]
Pelargonium sidoides根提取物对完全弗氏佐剂诱导的关节炎大鼠足部水肿、一氧化氮信号传导和滑膜血管变化的影响
Samime Sarli Gunduz,Dikmen Dokmeci,Ozgur Gunduz et al.
Samime Sarli Gunduz et al.
Rheumatoid arthritis (RA) is characterized by chronic synovitis with pannus formation and progressive joint destruction. Pannus growth relies on angiogenesis, and nitric oxide (NO) contributes to vascular and inflammatory signaling. Althoug...
Therapeutic potential of fucoidan from a persian gulf alga (Sargassum tenerrimum) in rheumatoid arthritis: In vivo evaluation in a rat model [0.03%]
伊朗霍尔木兹海峡海域产硫酸化多糖FC-10对胶原诱导型关节炎大鼠的治疗作用研究
Leila Mahmoudzadeh,Seyyed Meysam Abtahi Froushani,Seyede Soraya Mahmoudi
Leila Mahmoudzadeh
Fucoidan, due to its anti-inflammatory and immune-modulating effects, shows promise for the treatment of rheumatoid arthritis (RA). This study tested fucoidan from the Persian Gulf algae Sargassum tenerrimum on adjuvant-induced RA in Wistar...
Anti-inflammatory activity of Silver Nanoparticles (AgNPs): An Updated Systematic review from in vivo, and in vitro studies [0.03%]
银纳米颗粒（AgNP）的抗炎作用：来自体内和体外研究的系统性综述更新
Stuthi Nair,Abrar Ansari,Shaziya Khan et al.
Stuthi Nair et al.
Inflammation is a fundamental immune response implicated in the pathogenesis of chronic diseases, tissue injury, cancer, and aging. Conventional anti-inflammatory therapies, though effective, are usually limited by systemic toxicity and lon...
Laminarin attenuates neuroinflammation in MPTP-induced parkinson's disease mouse model via inhibiting dectin-1/Syk/NF-κB signaling [0.03%]
岩藻糖通过抑制dectin-1/syk/nf-κb信号通路缓解l-多巴诱导的小鼠帕金森病神经炎症作用
Rui-Yue Zhao,Mei Zhang,Xiao-Wen Wang et al.
Rui-Yue Zhao et al.
From anthelmintic to neurotherapeutic: exploring the regenerative potential of niclosamide in sciatic nerve injury [0.03%]
从驱虫到神经治疗：尼氯霜在坐骨神经损伤中的再生潜力探究
Ali Darabniya,Reza Fazeli,Sara Shahriari et al.
Ali Darabniya et al.