Decoding LL-37: Structure and antimicrobial mechanisms against microbial threats [0.03%]
揭开封丽素LL-37的神秘面纱：结构及其对抗微生物威胁的作用机制
Alireza Neshani,Hosna Zare,Nooshin Sadat Ghiasi et al.
Alireza Neshani et al.
Introduction: The emergence of antibiotic-resistant pathogens is a significant global health concern that necessitates the development of new antimicrobial drugs. Due to its broad-spectrum action against bacteria, fungi, ...
Inhibition of EgRad50 leads to impaired DNA repair in Echinococcus granulosus sensu stricto [0.03%]
EgRad50抑制导致细粒棘球蚴DNA修复受损
Jinlong Zhao,Shaoquan Xu,Yun Du et al.
Jinlong Zhao et al.
The parasitic disease known as cystic echinococcosis (CE) is a significant zoonotic condition caused by Echinococcus granulosus sensu lato (s.l.). The current lack of safe and effective pharmacological treatments necessitates urgent efforts...
Gashaw Azanaw Amare,Yenesew Mihiret Wondimagegn,Adane Adugna et al.
Gashaw Azanaw Amare et al.
Interleukin-25 (IL-25) is a crucial cytokine in coordinating type 2 immunity against gut-dwelling helminths. IL-25 is produced by a variety of cells, including epithelial and immune cells, and primarily stimulates Th2-type immune responses ...
Molecular epidemiology of Trypanosoma cruzi I infection in northern Argentina [0.03%]
阿根廷北部的克鲁兹锥体虫I型感染的分子流行病学研究
N P Macchiaverna,L P Quebrada-Palacio,G F Enriquez et al.
N P Macchiaverna et al.
Trypanosoma cruzi I (TcI) infects a broad range of mammalian and triatomine species across the Americas and displays broad genetic diversity. The transmission cycles of TcI remain poorly understood. We investigated whether TcI parasites fro...
Correlations between incidence of syphilis and frequencies of human leukocyte antigens haplotypes in China: An ecological study [0.03%]
中国不同HLA单倍型频率地区之间梅毒发病相关性的生态学研究
Wei-Jing Lin,Hong-Fei Mi,Ning-Dai Chen et al.
Wei-Jing Lin et al.
In China, the incidence of syphilis varies across different regions, as do the frequencies of HLA haplotypes. The progression and stages of syphilis infection may be associated with HLA polymorphisms. This study employed an ecological study...
Exploring the effect of the foodborne pathogen Bacillus cereus on the growth, immunity, and gut microbiota of mice [0.03%]
探索食源性病原菌芽胞杆菌(Bacillus cereus)对小鼠生长、免疫及肠道微生物的影响
Xueqi Teng,Chengwen Song,Jing Hang
Xueqi Teng
Bacillus cereus, a common spore-forming bacterium, is a major cause of foodborne illness worldwide. This study investigated its effects on mouse physiology and wellbeing-including body-weight trajectory, digestive/oxidative biochemistry, li...
Phylodynamic analysis of recent bovine viral diarrhea viruses in the Republic of Korea [0.03%]
最近在大韩民国的牛病毒性腹泻病毒的谱系动力学分析
Hyung-Chul Cho,Jaehyeok Song,Kyoung-Seong Choi
Hyung-Chul Cho
Bovine viral diarrhea virus (BVDV) is a globally distributed and economically significant viral pathogen in the cattle industry. Despite ongoing circulation, molecular evolutionary and phylodynamic data on BVDV in the Republic of Korea (ROK...
Virulence comparison and pathological impacts of three clinical Klebsiella pneumoniae isolates in a zebrafish larval model [0.03%]
三种临床克雷伯氏肺炎菌株的致病性比较及对斑马鱼幼虫模型的影响
Yanfei Jing,Ke Yu,Hai-Yan Yu et al.
Yanfei Jing et al.
Klebsiella pneumoniae (Kp) can cause infections in communities and hospitals. After a report of a first highly virulent strain, it has now become the important pathogens that threatens human health and can often infect patients in intensive...
Genotype diversity and evolution of noroviruses GI.3[P13] associated acute gastroenteritis outbreaks in Beijing, China from 2016 to 2019 [0.03%]
北京诺如病毒GI.3[P13]基因分型多样性及2016-2019年急性胃肠炎暴发的进化分析
Lingyu Shen,Jiamei Fu,Baiwei Liu et al.
Lingyu Shen et al.
Objectives: This study aimed to characterize the epidemiological, clinical, and genomic features of norovirus GI.3[P13] outbreaks in Beijing from 2016 to 2019. ...
Genomic insights into Erwinia amylovora prophages: Diversity, defense strategies, and phage-host coevolution [0.03%]
欧文氏菌天冬氨酸菌株噬菌体的基因组学见解：多样性、防御策略及与宿主的协同进化
Mohammadreza Rahimian,Bahman Panahi
Mohammadreza Rahimian
Erwinia amylovora, the causative agent of fire blight in Rosaceae plants like apple and pear, is a major agricultural pathogen responsible for significant economic losses. This gram-negative phytopathogen has the potential to acquire antibi...