Localization of angiotensin-(1-7) and Mas receptor in the rat ovary throughout the estrous cycle [0.03%]
整个发情周期中大鼠卵巢内血管紧张素-(1-7)和Mas受体的定位研究
Virginia M Pereira,Fernando M Reis,Geovanni D Cassali et al.
Virginia M Pereira et al.
We have previously demonstrated the presence of Angiotensin (Ang)-(1-7) in rat ovary homogenates and its stimulatory effect on estradiol and progesterone production. The present study was undertaken to identify the cellular localization of ...
Histidine kinase NME1 and NME2 are involved in TGF-β1-induced HSC activation and CCl4-induced liver fibrosis [0.03%]
组氨酸激酶NME1和NME2参与TGF-β1诱导的HSC活化和CCl4诱导的肝纤维化过程
Hui Gong,Zhiqiang Fan,Dan Yi et al.
Hui Gong et al.
Histidine phosphorylation (pHis) was first reported in 1962. There are few studies on pHis because of the thermal and acidic instability of pHis and the lack of specific methods to detect it. pHis has two isomers of 1-phosphate histidine (1...
The use of multiplex staining to measure the density and clustering of four endometrial immune cells around the implantation period in women with recurrent miscarriage: comparison with fertile controls [0.03%]
多重染色技术在复发性流产妇女种植期测量子宫内膜四种免疫细胞的密度和聚集情况与育龄对照组的比较研究
Yiwei Zhao,Xiaoyan Chen,Tao Zhang et al.
Yiwei Zhao et al.
Serval studies showed an increased uterine natural killer cell density in women with recurrent miscarriage. However, no study has previously investigated the density and clustering of major immune cells simultaneously in precisely timed end...
Serum LUCAT1 implicates the pathogenesis of muscle-invasive bladder cancer via targeting miR-199a-5p and miR-199b-5p [0.03%]
血清LUCAT1通过靶向miR-199a-5p和miR-199b-5p参与肌肉浸润性膀胱癌的发生发展过程
Yong Zhou,Xuejing Song,Xiameng Li et al.
Yong Zhou et al.
Muscle-invasive bladder cancer (MIBC) is a common malignancy of urinary system cancers, accounting for about 1/3 of all newly diagnosed bladder cancer cases. Due to its strong metastasis, the 5-year survival of MIBC is less than 50%, and in...
Down-regulation of SETD6 protects podocyte against high glucose and palmitic acid-induced apoptosis, and mitochondrial dysfunction via activating Nrf2-Keap1 signaling pathway in diabetic nephropathy [0.03%]
SETD6的下调通过激活糖尿病肾病中Nrf2-Keap1信号通路保护足细胞免受高葡萄糖和棕榈酸诱导的凋亡及线粒体功能障碍
Xiang Wang,Qiling Liu,Deqin Kong et al.
Xiang Wang et al.
Diabetic nephropathy (DN), a serious complication of hyperglycemia, is one of the most common causes of end-stage renal disease (ESRD). Glomerular podocyte injury is a major mechanism that leads to DN. However, the mechanisms underlying pod...
Lipid mass spectrometry imaging and proteomic analysis of severe aortic stenosis [0.03%]
严重主动脉瓣狭窄的脂质质谱成像和蛋白质组学分析
Jihyeon Lim,Jennifer T Aguilan,Rani S Sellers et al.
Jihyeon Lim et al.
Severe aortic stenosis (AS) is prevalent in adults ≥ 65 years, a significant cause of morbidity and mortality, with no medical therapy. Lipid and proteomic alterations of human AS tissue were determined using mass spectrometry imaging (MSI...
A new approach for examining the neurovascular structure with phalloidin and calcitonin gene-related peptide in the rat cranial dura mater [0.03%]
用肌动蛋白和降钙素基因相关肽观察大鼠颅顶窦神血管结构的新方法
Jia Wang,Dongsheng Xu,Jingjing Cui et al.
Jia Wang et al.
The neurovascular structures in the cranial dura mater have been studied with various histological techniques in the past years. In order to obtain a proper approach to reveal the detailed structures, different labeling methods for the cran...
Overexpression of PREX1 in oral squamous cell carcinoma indicates poor prognosis [0.03%]
口腔鳞状细胞癌中PREX1的过表达预示着预后不良
Shu-Cheng Wan,Hao Wu,Hao Li et al.
Shu-Cheng Wan et al.
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger (P-Rex) proteins control many fundamental cellular functions including cell migration, actin cytoskeletal rearrangement and adhesion in many cancers. However, P-Rex1 expressio...
Spatiotemporal expression of neurogenic locus notch homolog protein 1 in developing caudal spinal cord of fetuses with anorectal malformations from ETU-fed rats [0.03%]
ETU喂养的大鼠胎儿肛门直肠畸形尾侧脊髓NOTCH1蛋白的时空表达特性研究
Zhonghua Yang,Huimin Jia,Yuzuo Bai et al.
Zhonghua Yang et al.
Complications, such as fecal soiling, incontinence, and constipation, are major health issues for patients with anorectal malformations (ARMs) after surgery. Dysplasia of the caudal spinal cord is an increasingly pivotal area in the field o...
Mechanical adaptation of synoviocytes A and B to immobilization and remobilization: a study in the rat knee flexion model [0.03%]
滑膜细胞A和B对固定和再活动的机械适应性：大鼠膝关节屈曲模型中的研究
Haodong Zhou,Guy Trudel,Odette Laneuville
Haodong Zhou
The objective of this study was to quantify the in vivo response of synoviocytes type A and B in the posterior joint capsule to knee immobilization and remobilization. Also, to correlate the immunohistochemical data with selected mRNA expre...