Circ_0091702 serves as a sponge of miR-545-3p to attenuate sepsis-related acute kidney injury by upregulating THBS2 [0.03%]
circRNA circ_0091702通过上调THBS2充当miR-545-3p的海绵，从而减轻脓毒症相关急性肾损伤
Mingming Tan,Rongxin Bei
Mingming Tan
Circular RNA (circRNA) has been shown to play an important function in the progression of human diseases, including sepsis with acute kidney injury (AKI). However, the role and mechanism of circ_0091702 in sepsis-induced AKI have yet to be ...
Structural and functional relations between the connective tissue and epithelium of enamel organ and their role during enamel maturation [0.03%]
釉器官结缔组织与上皮的结构和功能关系及其在牙本质成熟期的作用
Anas F Mahdee,Ahmed H Ali,James I Gillespie
Anas F Mahdee
The morphological and possible functional interactions between the connective tissue and enamel organ cells were examined during the maturation phase of enamel formation, using immunohistochemical techniques. Decalcified mandibular sections...
Fascin promotes the invasion of pituitary adenoma through partial dependence on epithelial-mesenchymal transition [0.03%]
粘着斑诱导蛋白通过部分依赖上皮间质转化促进垂体腺瘤侵袭
Hong You,Jian Xu,Xiaochun Qin et al.
Hong You et al.
The aim of the present study was to investigate the role and potential regulatory mechanisms of fascin in the invasion and epithelial-to-mesenchymal transition of pituitary adenoma cells. A total of 30 specimens were assessed in the present...
LPS induces fibroblast-like synoviocytes RSC-364 cells to pyroptosis through NF-κB mediated dual signalling pathway [0.03%]
LPS诱导NF-κB介导的双信号通路促进滑膜成纤维细胞系RSC-364发生焦亡现象
Panpan Yang,Wei Feng,Congshan Li et al.
Panpan Yang et al.
Rheumatoid arthritis (RA) is a chronic, progressive, and systemic inflammatory joint disease characterized by synovial inflammation and joint damage. Abnormal activation of fibroblast-like synoviocytes is an initial event of synovial inflam...
Jian Zhang,Chensheng Lin,Yingnan Song et al.
Jian Zhang et al.
Tongue muscles are derived from mesodermal cells, while signals driven by cranial neural crest cells (CNCCs) regulate tongue myogenesis via tissue-tissue interaction. Based on such mechanisms of interaction, congenital tongue defects occur ...
The role of leukemia inhibitory factor in pathogenesis of pre-eclampsia: molecular and cell signaling approach [0.03%]
细胞因子LIF在子痫前期发病机制中的作用：分子及信号转导研究
Mehrnaz Abdolalian,Maryam Ebrahimi,Mahansadat Aghamirzadeh et al.
Mehrnaz Abdolalian et al.
Endothelial dysfunction is considered as the main hallmark of Preeclampsia (PE). Despite the unknown pathogenesis of PE, different possible causes have been suggested in various studies. In this review, we first studied the Leukemia inhibit...
Long noncoding HOXA11-AS knockdown suppresses the progression of non-small cell lung cancer by regulating miR-3619-5p/SALL4 axis [0.03%]
长链非编码RNA HOXA11-AS通过调控miR-3619-5p/SALL4轴促进非小细胞肺癌进展及其机制研究
Hongwei Xia,Qingling Niu,Yanguang Ding et al.
Hongwei Xia et al.
Accumulating evidence suggested that many long noncoding RNAs (lncRNAs) were widely involved in the development and progression of non-small cell lung cancer (NSCLC). However, the roles of lncRNA homeobox A11 antisense (HOXA11-AS) and its u...
Iron biodistribution profile changes in the rat spleen after administration of high-fat diet or iron supplementation and the role of curcumin [0.03%]
高脂肪饮食或铁补充剂对小鼠铁生物分布的影响及姜黄素的作用机制研究
Aziz Awaad,Hekmat Osman Abdel Aziz
Aziz Awaad
Curcumin as active metal chelating and antioxidant agent has a potential role in metal reduction and free radicals' neutralization in tissues. Of note, long-term administration of high fat diet (HFD) is considered as a main factor of blood ...
Up-regulation of DNA2 results in cell proliferation and migration in endometriosis [0.03%]
DNA2上调导致子宫内膜异位症中的细胞增殖和迁移
Xinyan Wang,Wenjie Zeng,Sheng Xu et al.
Xinyan Wang et al.
Accumulating evidence has suggests that women with advanced endometriosis exhibit alterations in the expression of genes in the endometrium compared to healthy controls. Furthermore, replication stress is a characteristic feature of cancer ...
Modulation of vigabatrin induced cerebellar injury: the role of caspase-3 and RIPK1/RIPK3-regulated cell death pathways [0.03%]
调控 Vigabatrin 诱导的小脑损伤：caspase-3 和 RIPK1/RIPK3 调控的细胞死亡通路的作用
Marwa Abd El-Kader,Eman Hamza,Randa El-Gamal et al.
Marwa Abd El-Kader et al.
Vigabatrin is the drug of choice in resistant epilepsy and infantile spasms. Ataxia, tremors, and abnormal gait have been frequently reported following its use indicating cerebellar involvement. This study aimed, for the first time, to inve...