Bioinformatics screening identifies USP9X as a pathogenic gene underlying thyroid and breast cancer comorbidity [0.03%]
生物信息学筛选鉴定USP9X为甲状腺癌和乳腺癌共病的致病基因
Siping Xiong,Yimin Guo,Miao Zhang et al.
Siping Xiong et al.
The co-occurrence of thyroid cancer (TC) and breast cancer (BC) has attracted much attention in recent years. The aim of the study was to explore the potential molecular mechanisms in the comorbidity of TC and BC. We identified the differen...
Correction: TAK-242 inhibits toll-like receptor-4 signaling and attenuates cancer-associated muscle atrophy via the p38-C/EBPβ pathway [0.03%]
校正：TAK-242通过p38-C/EBPβ途径抑制TLR-4信号传导并缓解癌症相关性肌肉萎缩
Yongfei You,Zhouzhou Su,Haozheng Wang et al.
Yongfei You et al.
Published Erratum
Journal of molecular histology. 2026 Jul 8;57(4):224. DOI:10.1007/s10735-026-10854-8 2026
Extremely low-frequency pulsed electromagnetic fields induce apoptotic, oxidative stress, inflammatory and aquaporin-related kidney alteration [0.03%]
极低频脉冲电磁场诱导的肾细胞凋亡、氧化应激、炎症和水通道蛋白相关改变
Merve Pekince Özöner,Ugur Seker,Cemil Sert et al.
Merve Pekince Özöner et al.
Extremely low-frequency pulsed electromagnetic fields are used as a biotherapy method in various medical and experimental applications. However, the cellular effects of prolonged or intense exposure remain unclear. This study aimed to evalu...
KPNA2 knockdown suppresses gastric cancer progression through modulation of the β-catenin/EMT signaling axis, inducing cell cycle arrest, apoptosis, and reduced metastatic capacity [0.03%]
KPNA2敲低通过调节β-连环素/上皮间质转化信号轴抑制胃癌进展、诱导细胞周期停滞、凋亡和降低转移能力
Haoyu Zhu,Tianli Niu,Shichun Feng et al.
Haoyu Zhu et al.
Karyopherin subunit alpha 2 (KPNA2) has been implicated in a variety of human diseases, particularly cancer. This study aimed to elucidate the role of KPNA2 in the development and progression of gastric cancer (GC). Bioinformatics analyses ...
Lasiokaurin suppresses hepatocellular carcinoma proliferation and induces apoptosis via the JAK2/STAT3 pathway [0.03%]
Lasiokaurin通过JAK2/STAT3信号通路抑制肝癌细胞增殖并诱导凋亡
Hu Tian,Huiling Zhou,Yu Ouyang et al.
Hu Tian et al.
The antitumor effects of Lasiokaurin (LAS), a natural compound derived from traditional Chinese medicine extracts, remain poorly understood in hepatocellular carcinoma (HCC). Therefore, this study investigates the anticancer effects of LAS ...
Arctiin activates CB2R to regulate the TRAF6-STAT1/6 pathway maintain macrophage M1/M2 homeostasis [0.03%]
_arctiin通过激活cb2r调节traf6-stat1/6通路维持巨噬细胞m1/m2平衡
Jie Lin,Chengyu Wang,Lei Han et al.
Jie Lin et al.
Immune rejection after liver transplantation remains a major challenge impacting the long-term survival of liver transplant recipients. Inhibiting macrophage M1 polarization exerts a positive effect on alleviating post-transplant immune rej...
BRCC3 promotes progression and immune evasion in non-small cell lung cancer through regulation of PD-L1 and B7-H3 [0.03%]
BRCC3通过调节PD-L1和B7-H3促进非小细胞肺癌进展和免疫逃逸
Kai Liu,Qun Shen,Chaochao Wei et al.
Kai Liu et al.
While elevated levels of the deubiquitinating enzyme BRCC3 have been documented in a range of cancers, its capacity to influence immune checkpoint expression or enable tumor immune evasion in non-small cell lung cancer (NSCLC) remains uncha...
The protective role of vitamin E against omeprazole-induced liver alterations in male wistar rats (Rattus norvegicus) [0.03%]
维生素E对雄性Wistar大鼠（Rattus norvegicus）奥美拉唑致肝损伤的保护作用
Zozan Abdullah Ibrahim,Intissar Numman Waheed,Yahya Ahmed Mohammed
Zozan Abdullah Ibrahim
Due to the limited information available regarding the effect of Omeprazole (OM) on rats' liver function. This study aimed to elucidate the impact on liver morphology, hepatic enzymes, liver weight, and electrolytes in male Wistar rats. Fif...
Zingerone supplementation stimulates germ cell proliferation, inhibits apoptosis and modulates autophagy and ferroptosis in the mice testis [0.03%]
姜辣素通过刺激生精细胞增殖、抑制细胞凋亡及调节自噬和铁死亡改善小鼠生精障碍
Miti Jerang,Guruswami Gurusubramanian,Vikas Kumar Roy
Miti Jerang
The aim of this study was to evaluate the effects of zingerone supplementation on testicular spermatogenesis by analyzing germ cell proliferation, cell survival, and antioxidant status in the testis of mice. Zingerone was administered orall...
Vitamin D3 promotes regression of endometrial implants comparable to buserelin in a rat model of endometriosis [0.03%]
维生素D3可促进子宫内膜异位症模型大鼠病灶退化且效果与亮丙瑞林相当
Ayşe Köylü,Suna Ömeroğlu,Saadet Özen Akarca Dizakar et al.
Ayşe Köylü et al.
Buserelin, a gonadotropin-releasing hormone agonist, reduces gonadotropin and estrogen levels and is commonly used to alleviate the symptoms of endometriosis. Vitamin D3 has been reported to exhibit anti-inflammatory and pro-apoptotic prope...