Polydatin attenuates lead-induced hematotoxicity and neuroinflammation: insights from hematological, cytokine, and histopathological analyses in Wistar rats [0.03%]
茋红通过血液学、细胞因子和组织病理学分析减轻铅引起的血液毒性和神经炎症反应：在Wistar大鼠中的研究
Salisu Muhammad Highab,Abdulhakim Abubakar,Sanusi Muhammad Salisu et al.
Salisu Muhammad Highab et al.
QiangGuYin-containing serum improves osteogenic differentiation via regulating osteoclast-derived exosomal miR-27b-3p [0.03%]
强骨饮含药血清通过调控破骨细胞源性外泌体中miR-27b-3p促进成骨分化
Binbin Tang,Shengjia Hu,Yifeng Yuan et al.
Binbin Tang et al.
Osteoclast-derived exosomes play a critical role in suppressing osteogenic differentiation, contributing to postmenopausal osteoporosis (PMOP). QiangGuYin (QGY), a traditional Chinese herbal formula, has demonstrated efficacy in alleviating...
Integrative analysis of single-cell and bulk RNA sequencing data using machine learning identifies PTGDS as a key subsynovial fibroblast gene in osteoarthritis [0.03%]
利用机器学习集成分析单细胞和批量RNA测序数据，识别PTGDS为骨关节炎下游纤维母细胞关键基因
Weiwei Wang,Chicheng Niu,Canbin Zhao et al.
Weiwei Wang et al.
Effects of Centella asiatica extract on burn wound healing in streptozotocin-induced diabetic rats: a pathological and molecular evaluation [0.03%]
辣根藤提取物对链尿佐霉素诱导的糖尿病大鼠烧伤创面愈合的影响：病理和分子学评价
Osman Dağar,Mustafa Ortatatlı
Osman Dağar
This study investigated the pathological and molecular effects of Centella asiatica extract-based cream and ointment formulations on burn wound healing in streptozotocin-induced diabetic rats. A total of 92 female Wistar albino rats were as...
The anti-ulcerative potential of Berberine on the rat model of inflammatory bowel disease [0.03%]
小檗碱对溃疡性结肠炎模型大鼠的治疗作用研究
Ghadha Ibrahim Fouad,Hanan F Aly,Dalia A Taha et al.
Ghadha Ibrahim Fouad et al.
Ulcerative colitis (UC) is a global inflammatory bowel disease (IBD) and is a chronic mucosal inflammation of the large intestine. UC is accompanied by the increment in the production and release of pro-inflammatory mediators. Due to the im...
Protective role of Actovegin against Cisplatin-evoked testicular damage: evidence from a rat model [0.03%]
Actovegin对顺铂所致睾丸损伤的保护作用：大鼠模型证据
Mennat Allah A Saqr,Esraa S Habiba,Sarah Ahmed Hassan et al.
Mennat Allah A Saqr et al.
Testicular dysfunction and infertility are major concerns for men on Cisplatin. Excess reactive oxygen species produced by Cisplatin cause oxidative stress, impairing sperm quality. Actovegin is a deproteinized calf blood extract containing...
Cx43 modulates malignant phenotypes in bladder cancer cells via the c-Src/PTEN/FAK axis [0.03%]
缝隙连接蛋白Cx43通过c-Src/PTEN/FAK轴调节膀胱癌细胞的恶性表型
Qiang Chi,Hui Xu,Hongyang Li et al.
Qiang Chi et al.
Bladder cancer (BC), a leading urogenital malignancy with high mortality, lacks effective early biomarkers. Connexin 43 (Cx43), encoded by GJA1, regulates tumor growth via protein interactions and phosphorylation. While dysregulated in BC, ...
Dendrobium officinale polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction [0.03%]
石斛多糖通过抑制炎症和线粒体功能障碍来缓解特应性皮炎
Bijun Zeng,Gufen Jiang,Chang Wang et al.
Bijun Zeng et al.
Atopic dermatitis (AD) is a chronic inflammatory skin disorder marked by immune dysregulation and oxidative stress. Current therapies, such as corticosteroids, have side effects, necessitating new treatments. This study investigates the the...
Mucuna pruriens extract as prebiotic and Lactobacillus rhamnosus as probiotic intervention mitigated histological changes in DNCB-induced colitis via GLP-1/Nrf2/NF-κB axis regulation [0.03%]
密蒙花提取物作为益生元和鼠李糖乳杆菌作为益生菌通过GLP-1 / Nrf2 / NF-κB轴调节缓解二硝基氯苯诱导的结肠炎的组织学变化
Lokesh Nama,Md Abubakar,Rajni Daksh et al.
Lokesh Nama et al.
Ocimum tenuiflorum L. extracts attenuate polycystic ovarian syndrome in letrozole treated female Wistar rats through modulation of iNOS, COX-2, IL-1β and TNF-α [0.03%]
Ocimum tenuiflorum L.提取物通过调节iNOS、COX-2、IL-1β和TNF-α减轻来曲唑治疗的雌性Wistar大鼠多囊卵巢综合征
Safeena Rashid,Waseem Younis Khan,Sana Hafiz et al.
Safeena Rashid et al.
Polycystic ovary syndrome (PCOS) is a prevalent endocrine abnormality affecting the women of child bearing age. PCOS markedly raises the chances of infertility, cardiovascular disease, and increased blood pressure. Ocimum tenuiflorum is kno...