Avoiding big data pitfalls [0.03%]
避免大数据的陷阱
Pablo Lamata
Pablo Lamata
Clinical decisions are based on a combination of inductive inference built on experience (ie, statistical models) and on deductions provided by our understanding of the workings of the cardiovascular system (ie, mechanistic models). In a si...
Emanuele Marzetti,Emanuela D&#x;Angelo,Giulia Savera et al.
Emanuele Marzetti et al.
Brown adipose tissue (BAT) has evolved as a unique thermogenic organ that allows placental mammals to withstand cold environmental temperatures through the dissipation of metabolic energy in the form of heat. Although traditionally believed...
Gene therapy for cardiovascular manifestations of lysosomal storage diseases [0.03%]
溶酶体贮积病心血管表现的基因治疗
Meg M Sleeper,Mark E Haskins,Katherine P Ponder
Meg M Sleeper
Cardiac disease causes morbidity in several lysosomal storage diseases, which are the result of deficient activity of lysosomal enzymes. Mucopolysaccharidosis (MPS) causes aortic and valvular disease, Pompe disease causes cardiac muscle wea...
E Dale Abel
E Dale Abel
The growing worldwide epidemic of obesity and diabetes portends a significant increase in cardiovascular disease. Obesity is associated with insulin resistance, and there is growing evidence that these conditions independently increase the ...
Birgit Kantor,Ronald S Kuzo,Thomas C Gerber
Birgit Kantor
Coronary computed tomographic angiography (CCTA) is a direct but minimally invasive method of visualizing coronary arteries. Acceptable indications for this technique include the assessment of suspected or known coronary artery anomalies, t...