The dynamic expression of canonical Wnt/β-catenin signalling pathway in the pathologic process of experimental autoimmune neuritis [0.03%]
经典Wnt/β-catenin信号通路在实验性自身免疫神经炎病理过程中的动态表达规律研究
Yin Liu,Shuping Liu,Sijia Pan et al.
Yin Liu et al.
Background: Guillain-Barré syndrome (GBS), an autoimmune disease and an acute inflammation disorder, is currently the most frequent cause of acute flaccid paralysis worldwide. EAN, an animal model of GBS, is a CD4+ T cell-mediated autoimmu...
Minoo Karimi,Farinaz Nasirinezhad,Ali Shahbazi et al.
Minoo Karimi et al.
Background and objectives: Hyperacusis is hypersensitivity and extreme response to the intensity of sound that is tolerable in normal subjects. The mechanisms underlying hyperacusis has not been well understood, specially the role of insula...
Relationship between generalized epileptic seizure and neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and neutrophil mediated inflammation [0.03%]
癫痫全面性发作与中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值及中性粒细胞介导的炎症之间的关系研究
Muzaffer Güneş,Hüseyin Büyükgöl
Muzaffer Güneş
Aim: There is a close relationship between systemic inflammation and epileptic seizure. Recently, neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) have been defined as significant inflammation biomarkers. In the present...
IL-1β-31/IL1-RA genetic markers association with idiopathic generalized epilepsy [0.03%]
细胞遗传标记与自身免疫性全身性癫痫的关系研究
Rujittika Mungmungpuntipantip,Viroj Wiwanitkit
Rujittika Mungmungpuntipantip
Unilateral cerebral cortical encephalitis with epilepsy: a possible special phenotype of MOG antibody-associated disorders [0.03%]
脑炎伴癫痫的单侧大脑皮层炎症可能是髓鞘少突胶质糖蛋白抗体相关障碍的特殊表型
Ran Tao,Chuan Qin,Man Chen et al.
Ran Tao et al.
Myelin oligodendrocyte glycoprotein (MOG) antibody-related encephalomyelitis is an increasingly recognized entity with heterogeneity in phenotype. Among all clinical phenotypes, encephalitis restricted to cerebral cortex might be most easil...
Investigation on beneficial role of l-carnosine in neuroprotective mechanism of ischemic postconditioning in mice: possible role of histidine histamine pathway [0.03%]
左卡尼丁在小鼠缺血后处理神经保护机制中的有益作用及组氨酸-组胺通路的可能介导效应的研究
Jasleen Kaur Virdi,Amritansh Bhanot,Amteshwar Singh Jaggi et al.
Jasleen Kaur Virdi et al.
Objective: The present study was undertaken to investigate the possible role of histidine-histamine pathway in the neuroprotective effects produced by L-carnosine hand in hand with ischemic postconditioning in the animal ...
Compound heterozygous mutations in the ALDH3A2 gene cause Sjögren-Larsson syndrome: a case report [0.03%]
ALDH3A2基因的复合杂合突变导致Sjögren-Larsson综合征1例报告
Yi-Dan Liu,Hong-Juan Lin,Chun-Yan Li et al.
Yi-Dan Liu et al.
Purpose: Sjögren-Larsson syndrome is a rare, autosomal, recessive neurocutaneous disorder caused by mutations in the ALDH3A2 gene, which encodes the fatty aldehyde dehydrogenase enzyme. Deficiency in fatty aldehyde dehydrogenase results in...
Role of the mitochondrial calcium uniporter in Mg2+-free-induced epileptic hippocampal neuronal apoptosis [0.03%]
镁离子缺乏诱导的癫痫海马神经元凋亡中线粒体钙单向转运蛋白的作用机制研究
Yingjiao Li,Cui Wang,Yajun Lian et al.
Yingjiao Li et al.
Mitochondrial Ca2+ overload is closely associated with seizure-induced neuronal damage. The mitochondrial calcium uniporter (MCU) plays a crucial role in regulating mitochondrial Ca2+ homeostasis. However, the role of the MCU in seizure-ind...
Activating transcription factor 6 reduces Aβ1-42 and restores memory in Alzheimer's disease model mice [0.03%]
激活转录因子6可降低阿尔茨海默病模型小鼠的Aβ1-42并改善其学习记忆能力
Yayun Du,Xiaoli Liu,Xilin Zhu et al.
Yayun Du et al.
Objectives: Amyloid plaques are the most important pathological hallmarks of Alzheimer's disease. The deposition of amyloid plaques will cause ER Stress. Activating Transcription Factor 6(ATF6) is a sensor of ER Stress. H...
Time estimation exposure modifies cognitive aspects and cortical activity of attention deficit hyperactivity disorder adults [0.03%]
时间估计暴露可改变注意缺陷多动障碍成人患者的认知方面及皮层活动
Rhailana Medeiros Fontes,Victor Marinho,Valécia Carvalho et al.
Rhailana Medeiros Fontes et al.
Aim: This study investigated whether time-estimation task exposure influences the severity of Attention Deficit Hyperactivity Disorder (ADHD), as well as theta band activity in the dorsolateral prefrontal cortex and ventr...