Identification of PANoptosis-related biomarkers in spinal cord injury (SCI) through multi-omics analysis and machine learning [0.03%]
Song Xu,Guozhu Wang,Xiongwen Zhang et al.
Song Xu et al.
Background: Spinal cord injury (SCI) is a severe neurological disorder lacking early diagnostic biomarkers and precise therapeutic targets. PANoptosis, a combined cell death process involving apoptosis, necroptosis, and p...
The predictive value of serum CXCL2 and CXCL8 levels for early neurological deterioration in patients with penetrating artery disease-type ischaemic stroke [0.03%]
Yi Zhong,Bei Liu
Yi Zhong
Objective: To evaluate whether serum C-X-C motif chemokine ligand 2 (CXCL2) and C-X-C motif chemokine ligand 8 (CXCL8) predict early neurological deterioration (END) in penetrating artery disease (PAD)-type ischaemic stro...
Clinical association of serum miR-524-5p levels with injury severity and prognostic outcomes in traumatic brain injury [0.03%]
血清miR-524-5p水平与创伤性脑损伤严重程度及预后的关系临床研究
Xianfeng Yu,Zhenzhen Hu
Xianfeng Yu
Background: Traumatic Brain Injury (TBI) has a complex pathology, with no specific biomarkers for diagnosis/prognostic stratification. miRNAs are key regulators of TBI pathological progression. ...
Lumbar Spine Disorder Detection using Segmentation and IBN-MGNet Classification with Enhanced Feature Extraction [0.03%]
基于分割和改进特征提取的IBN-MGNet分类的腰椎病变检测方法研究
Katepogu Surendra,B Eswara Reddy
Katepogu Surendra
Back pain affects millions worldwide, with lumbar spine disorders (LSDs) being a major contributing factor due to the spine's critical role in supporting body weight. This study aims to improve the detection of LSDs using advanced deep lear...
Bidirectional Mendelian randomization study of causal associations between white-matter structural connectivity and multiple sclerosis [0.03%]
基于双向孟德尔随机化研究的白质结构连接与多发性硬化的因果关联分析
Zhenxing Yu,Haijun Chen,Zhipeng Zhang et al.
Zhenxing Yu et al.
Background: Multiple sclerosis (MS) is associated with widespread network disruption, but whether specific white-matter structural connectivity (WMSC) phenotypes contribute causally to MS susceptibility remains unclear. ...
Methylation of tenascin XB mediated by methyltransferase-like 3 can effectively suppress neural injury and cellular apoptosis induced by ischemic stroke [0.03%]
甲基转移酶样蛋白3介导的神经营养素XB甲基化可有效抑制缺血性脑卒中诱导的神经损伤和细胞凋亡
Lige Ding,Xiaojie Feng,Fan Gao
Lige Ding
Background: Ischemic stroke (IS), a cerebrovascular disorder due to brain vessel blockage, poses a direct life-threatening risk. Tenascin XB (TNXB), a glycoprotein, is key in regulating extracellular matrix structure and ...
Scalable Quantum Non-Local Neural Network Optimized with Tyrannosaurus Algorithm for Brain tumor Detection using MRI Images [0.03%]
使用MRI图像进行脑肿瘤检测的可扩展量子非局部神经网络，采用暴龙算法优化
C Pabitha,Gaurav Agrawal,L Guganathan et al.
C Pabitha et al.
Early and reliable detection of brain tumors from magnetic resonance imaging (MRI) is essential for timely clinical diagnosis and treatment planning. However, automated tumor detection continues to be challenging due to the heterogeneous na...
Platelet-to-lymphocyte ratio as an inflammatory marker associated with stroke severity in acute ischemic stroke: a prospective observational study [0.03%]
血小板淋巴细胞比值在急性缺血性卒中患者炎症反应中的作用及与神经功能损伤的关系
Sathiyanarayanan Janakiraman,Kawiraj N,C Pravin Coumar
Sathiyanarayanan Janakiraman
Stroke is a major cause of disability and mortality in India, occurring as ischemic or hemorrhagic. Platelets drive thrombosis and inflammation, while lymphocytes exert anti-inflammatory effects. The platelet-to-lymphocyte ratio (PLR) refle...
Therapeutic role of miR-296-5p in hypertensive stroke through ACE2-dependent Edn1 suppression [0.03%]
miR-296-5p通过依赖ACE2的Edn1抑制在高血压性脑卒中中的治疗作用
Jibo Li,Feng Chen,Chanchan Liu et al.
Jibo Li et al.
Objective: This study investigated the mechanism of miR-296-5p in hypertensive stroke. Methods: Ten patients with acute stroke and ten ...
Self-Improved LeNet and Modified SegNet for Alzheimer's Disease Classification using MRI [0.03%]
基于MRI的自改善LeNet和改进型SegNet阿尔兹海默病分类方法研究
Rajasree Rs,Gopika G S,Supriya S et al.
Rajasree Rs et al.
Alzheimer's disease (AD) is the leading cause of dementia, typically affecting the elderly. It results in cognitive and memory loss with progression that can lead to death. Although the exact cause remains unclear, it is believed to involve...