Spatial memory deficits initiated by agroclavine injection or olfactory bulbectomy in rats are characterized by different levels of long-term potentiation expression in the hippocampus [0.03%]
嗅球切除或Agroclavine诱导的雄性大鼠空间记忆缺陷与海马区长期增强不同步
Vasily Vorobyov,Natalia Medvinskaya,Alexander Deev et al.
Vasily Vorobyov et al.
Aim: To clarify whether long-term potentiation (LTP) is the mechanism underpinning mnemonic processes. Mathrials and methods: We studied LTP in hippocampal slices from rats whose spatial memory deficit was produced by either olfactory bulbe...
Regulation of microRNAs by IRE1α in apoptosis: implications for the pathomechanism of neurodegenerative diseases [0.03%]
IRE1α调控microRNA在凋亡中的作用及其对神经退行性疾病发病机制的影响
Zhonghao Su,Lanyue Sheng,Ping Yu et al.
Zhonghao Su et al.
Although there are large differences in clinical and pathological features, age-related neurodegenerative diseases (NDs) share common pathogenetic mechanisms involving aggregation and deposition of misfolded proteins, which leads to progres...
Synergistic effect of glucocorticoids and IGF-1 on myogenic differentiation through the Akt/GSK-3β pathway in C2C12 myoblasts [0.03%]
糖皮质激素与IGF-1通过Akt/GSK-3β信号途径协同促进C2C12肌管分化的研究
Xiao-Bo Fang,Zu-Biao Song,Meng-Shu Xie et al.
Xiao-Bo Fang et al.
Purpose: Glucocorticoids are the only therapeutics that can delay the progression of Duchenne musculardystrophy (DMD), the most prevalent type of inherited neuromuscular disorder in males. However, beyond theiranti-inflammatory effects, glu...
Postpartum intracranial hypotension complicated by posterior reversible encephalopathy syndrome: a case report [0.03%]
产后颅内低压合并可逆性后部脑病综合征病例报告
Maria Chondrogiorgi,Anastasia K Zikou,Spiridon Konitsiotis et al.
Maria Chondrogiorgi et al.
Purpose: To present an unusual case of posterior encephalopathy syndrome (PRES) preceded by intracranial hypotension.Materials and Methods: We present a case of a 27-year-old parturient with an uneventful pregnancy that shortly after labor ...
The molecular basis of platelet biogenesis, activation, aggregation and implications in neurological disorders [0.03%]
血小板发生、活化、聚集的分子机制及其在神经疾病中的意义
Abhilash Ludhiadch,Abhishek Muralidharan,Renuka Balyan et al.
Abhilash Ludhiadch et al.
Platelets are anucleated blood constituents, vital for hemostasis and involved in the pathophysiology of several cardiovascular, neurovascular diseases as well as inflammatory processes and metastasis. Over the past few years, the molecular...
Vision treatment strategy for acute blindness in adolescent female with diffuse leptomeningeal glioneuronal tumor [0.03%]
青春期女性弥漫性软脑膜胶质神经元肿瘤所致急性失明的视觉康复治疗策略
Siqin Zhou,Miao Zhang,Huihui Wu et al.
Siqin Zhou et al.
Diffuse leptomeningeal glioneuronal tumor with the first symptom of acute rapid blindness in both eyes are rare in adolescents. We present a case of an adolescent female without a history of cancer who developed a dramatic loss of vision an...
Associations of ATG7 rs1375206 polymorphism and elevated plasma ATG7 levels with late-onset sporadic Parkinson's disease in a cohort of Han Chinese from southern China [0.03%]
ATG7基因多态性与血浆中ATG7水平升高与中国南方汉族人群特发帕金森病的关联研究
Xiyao Zhao,Yusen Chen,Li Wang et al.
Xiyao Zhao et al.
Background: Autophagy-related gene 7 (ATG7) plays a key role in autophagy and is strongly implicated in Parkinson's disease (PD). This study investigated the associations of rs1375206 polymorphism in ATG7 gene promoter and plasma ATG7 level...
lncRNA MALAT1 contributes to neuropathic pain development through regulating miR-129-5p/HMGB1 axis in a rat model of chronic constriction injury [0.03%]
长链非编码RNA MALAT1通过调节miR-129-5p/HMGB1轴参与慢性约束损伤大鼠模型神经病理性疼痛的发展
Xiaojing Ma,Hong Wang,Tieying Song et al.
Xiaojing Ma et al.
Backgrounds: Mounting studies pay attention to the functional roles of long non-coding RNAs (lncRNAs) in many human diseases including neuropathic pain. LncRNA MALAT1 has been indicated to serve as a critical mediator in neuropathic pain wi...
Tetrahydrocannabinol and cannabidiol oromucosal spray in resistant multiple sclerosis spasticity: consistency of response across subgroups from the SAVANT randomized clinical trial [0.03%]
克贝兰口腔黏膜喷雾剂治疗难治性多发性硬化症痉挛：SAVANT随机临床试验各亚组的疗效一致性分析
Sven G Meuth,Thomas Henze,Ute Essner et al.
Sven G Meuth et al.
Objective: To determine whether differences in disability status, spasticity severity, and spasticity duration at treatment start in patients with resistant multiple sclerosis (MS) spasticity might influence response to add-on tetrahydrocan...
Randomized Controlled Trial
The International journal of neuroscience. 2020 Dec;130(12):1199-1205. DOI:10.1080/00207454.2020.1730832 2020