Long-lasting tissue inflammatory processes trigger autoimmune responses to extracellular matrix molecules [0.03%]
持续的组织炎症过程引发对基底膜成分的自身免疫反应
Roberto Bei,Laura Masuelli,Camilla Palumbo et al.
Roberto Bei et al.
Extracellular matrix (ECM) remodeling is strongly favored by the conditions occurring in the inflammatory microenvironment and can lead to pathogenic reactions directed toward the ECM itself. Several reports have described autoimmune respon...
Taraneh Paravar,Delphine J Lee
Taraneh Paravar
The classification of thalidomide as an orphan drug with anti-inflammatory actions has led to its off-label use in conditions refractory to other medications. Although the observed clinical effects of thalidomide suggest it to have immunomo...
Potential role of NK cells in the induction of immune responses: implications for NK cell-based immunotherapy for cancers and viral infections [0.03%]
NK细胞在诱导免疫应答中的潜在作用:对基于NK细胞的癌症和病毒感染免疫治疗的意义
Hiroshi Terunuma,Xuewen Deng,Zahidunnabi Dewan et al.
Hiroshi Terunuma et al.
Natural killer (NK) cells recognize tumor cells and virus-infected cells and attack without being sensitized to antigens. The development of the antitumor/antivirus activities of NK cells is controlled by multiple mechanisms such as direct ...