[Polymorphism -786T>C (rs2070744) of the NOS3 gene as a potential risk factor for impaired autonomic regulation of the cardiovascular system in the age aspect] [0.03%]
年龄因素下一氧化氮合酶3基因多态性-786T>C（rs2070744）作为自主神经功能紊乱的危险因素的可能性研究
I N Bezmenova,I V Averyanova
I N Bezmenova
According to current understanding, aging is a complex process that is influenced by both genetic and environmental factors. Identifying reliable indicators of healthy aging is a significant challenge for modern science. Previous research h...
[Vascular dysfunction: processes due to aging, approaches to restorative therapy and prevention (part 1)] [0.03%]
血管功能障碍：老化引起的过程、修复治疗和预防的方法（一）
T V Shushpanova,N A Bokhan,I N Smirnova et al.
T V Shushpanova et al.
Currently, clinical, genetic and environmental factors of aging have been identified; it has been established that signs of human aging can be attributed to diseases due to their compliance with ICD-11 criteria. Causal events leading from e...
[Tumor necrosis factor receptors-1 in fibroblasts of human dermis in the process of physiological aging] [0.03%]
生理老化的人体真皮成纤维细胞肿瘤坏死因子受体-1的研究
A G Gunin,N N Golubtzova,T G Denisova et al.
A G Gunin et al.
The aim of this work was to examine the content of TNF receptors-1 in fibroblasts of human dermis from the development until 85 years old, and defining of a role of this protein age-dependent changes in the number of fibroblasts in the derm...
[The extracellular matrix of senescent stromal cells decreased secretion of SDF-1 and HGF by endothelium] [0.03%]
衰老间质细胞的细胞外基质降低内皮细胞分泌SDF-1和HGF的能力
D K Matveeva,D N Kashirina,A Y Ratushnyy
D K Matveeva
The process of mesenchymal stromal cells (MSCs) senescence is accompanied by alterations in their extracellular matrix (ECM), which has the potential to compromise cellular interactions within the perivascular niche. In this study, the effe...
[H2S as an activator of the NO-sGC signaling pathway in dilation of cerebral vessels: changes in aging] [0.03%]
[h2s作为no-sgc信号通路的激活因子参与脑血管舒张及其衰老相关变化]
O P Gorshkova
O P Gorshkova
The study included a comparative study of the contribution of nitric oxide (NO) and soluble guanylate cyclase (sGC) to hydrogen sulfide-mediated (H2S) dilation of the pial arteries in Sprague-Dawley rats aged 4 and 18 months. In vivo microg...
[Effect of semaglutide treatment on the body weight and the glucose, insulin and thyroid hormone levels in aging rats with diet-induced obesity] [0.03%]
司美格鲁肽对高脂喂养衰老小鼠体重及血糖、胰岛素和甲状腺激素水平的影响
K V Derkach,I V Fedorchuk,N E Basova et al.
K V Derkach et al.
Obesity, type 2 diabetes mellitus and associated thyroid diseases are most common among elderly patients. Glucagon-like peptide-1 receptor (GLP-1-R) agonists, including semaglutide, are a promising approach for their treatment, but their ef...
[Search for a new geroprotector: study of the effect of fucoxanthin on the main markers of aging in mice] [0.03%]
寻找新的抗衰老物质——富合维生素对小鼠主要衰老标志物的影响研究
A I Kapralov,I Y Maklakova,D Y Grebnev et al.
A I Kapralov et al.
Today, one of the key tasks of gerontology is the search for geroprotectors that are highly effective and safe. This paper presents data on the effect of fucoxanthin, a natural carotenoid, on aging markers in mice. Results are presented dem...
N E Garashchenko,N E Smurova,N V Semenova et al.
N E Garashchenko et al.
The paper presents the results of the gut microbiota study in menopausal women with sleep disorders based on different assessments of sleep quality. The study involved 96 menopausal women. Sleep quality was assessed using three questionnair...
[Projectional anatomy of the kidneys in older age groups: comparative analysis of somatotypes] [0.03%]
老年人肾投影解剖：体型比较分析
Y K Delalov,I U Vagabov,H M Bataev et al.
Y K Delalov et al.
The aim of the study was to conduct a comparative analysis of the projection anatomy of the kidneys in older individuals of various somatotypes with the determination of morphometric patterns and topographic and anatomical features to optim...
Comparative Study
Advances in gerontology = Uspekhi gerontologii. 2025;38(4):553-561. DOI: 2025
[Complexities of myocardial revascularization in patients over 75 years with acute coronary syndrome] [0.03%]
[急性冠脉综合征75岁以上患者复杂性心肌再血管化的临床结果分析]
T R Vildanov,N G Lukyanov,K L Kozlov et al.
T R Vildanov et al.
Acute myocardial infarction is the leading cause of hospitalization and mortality in elderly patients. The objective of this review is to demonstrate the importance of a comprehensive geriatric examination in cardiology, a balanced approach...