Yingfeng Wan,Preethi Reddi,Adam Fox et al.
Yingfeng Wan et al.
Hemorrhagic stroke, including subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), and intraventricular hemorrhage (IVH), is associated with high morbidity and mortality driven by secondary injury processes such as neuroinflammati...
EXPRESS: Haemorrhage, Hypercoagulability, and Ischaemia: Evolution of Brain Injury after Aneurysmal Subarachnoid Haemorrhage [0.03%]
急性脑出血后的脑损伤进展情况：蛛网膜下腔出血后颅内迟发性出血、高凝状态和缺血
Yuyang Wang,Jordan Fisker,Lipi Mishra et al.
Yuyang Wang et al.
Aneurysmal subarachnoid haemorrhage (aSAH) is a catastrophic cerebrovascular event associated with high early mortality and substantial long-term disability. Delayed cerebral ischaemia (DCI) is among its most severe complications and a prin...
EXPRESS: Somatotopic Homunculus Profiles of Motor Cortex and Corticospinal Tract in Aging [0.03%]
老龄人群中运动皮层和皮质脊髓束的体表拓扑特征研究
Jiaqi Wen,Chenyang Li,Li Jiang et al.
Jiaqi Wen et al.
Background: Motor performance declines with aging, yet how somatotopic subregions of the primary motor cortex (M1) and corticospinal tract (CST) show region-specific structural and functional changes during aging remains ...
EXPRESS: Bioenergetics of the combat sports brain: between risk and resilience [0.03%]
简讯：战斗运动对大脑生物能量的影响：风险与适应力之间的平衡
Damian Miles Bailey,Benjamin S Stacey,Kevin Cox et al.
Damian Miles Bailey et al.
Combat sports provide a unique human model in which cerebral ischaemia-reperfusion stress, adaptive neuroprotection, and impact-induced neurodegenerative risk coexist. Across striking and grappling disciplines, exercise-induced metabolic an...
EXPRESS: Stage-Dependent Deep Gray Matter Alterations in Cerebral Small Vessel Disease Revealed by 7T Quantitative Susceptibility Mapping [0.03%]
基于7T定量磁化率成像的脑小血管病不同阶段深灰质异常变化的影像研究
Yue Yuan,Shuai Jiang,Youjie Wang et al.
Yue Yuan et al.
Susceptibility alterations in deep gray matter (DGM) across clinical stages of cerebral small vessel disease (CSVD) remain unclear. In this case-control study, we used 7-tesla magnetic resonance imaging quantitative susceptibility mapping (...
EXPRESS: Cerebrovascular Reactivity Delay measured by Blood Oxygen Level Dependent Magnetic Resonance Imaging and Gas Challenges: A Systematic Review [0.03%]
基于血液氧水平依赖的磁共振成像和气体刺激检测脑血管反应性延迟的系统综述
Keelin Neamh Ridge,Joanna Wardlaw,Michael Thrippleton et al.
Keelin Neamh Ridge et al.
Background: Cerebrovascular reactivity (CVR), a promising marker of neurovascular responsiveness, is commonly measured using blood-oxygenation-level-dependent magnetic resonance imaging (BOLD-MRI) during a vasoactive gas ...
Higher fasting brain glucose is associated with lower gray matter volume in healthy adults [0.03%]
较高的空腹脑葡萄糖与健康成年人较低的灰质体积相关
Helena van Nieuwenhuizen,Botond B Antal,Antoine Hone-Blanchet et al.
Helena van Nieuwenhuizen et al.
Glucose hypometabolism is implicated in age-related neurodegeneration, with peripheral markers such as hyperglycemia and insulin resistance linked to increased dementia risk and brain atrophy. However, the degree to which peripheral and cer...
EXPRESS: Full functional knockout of Placental Growth factor primes the mouse neurovasculature for inflammation and injury [0.03%]
简报：胎盘生长因子完全敲除的小鼠神经血管易发生炎症和损伤
Daniel Alexander Rivera,Katelynn E Krick,Colin B Rogers et al.
Daniel Alexander Rivera et al.
The MarkVCID consortium investigating biomarkers for vascular contributions to cognitive impairment and dementia (VCID) found placental growth factor (PlGF) correlated with white matter hyperintensities and cognitive impairment. PlGF was th...
EXPRESS: Brain-derived tau: a promising biomarker for acute ischemic stroke [0.03%]
急性缺血性脑卒中源性tau蛋白标志物的发现与验证
Ji Hyun Park,Eng H Lo
Ji Hyun Park
Blood biomarkers for ischemic stroke have long been sought to complement imaging-based assessments of brain injury, but clinically useful markers with sufficient sensitivity and specificity remain limited. A recent study by Vlegels et al. s...
EXPRESS: Single-Cell Analysis of Microglia and Monocyte Dynamics Uncovers Distinct TNF-driven Neuroimmune Signatures in Humans after Intracerebral Hemorrhage [0.03%]
单细胞分析揭示人在脑出血后的小胶质细胞和单核细胞动力学及其独特的TNF驱动的神经免疫特征
Yuki Kawamura,Conor W Johnson,Jonathan DeLong et al.
Yuki Kawamura et al.
Innate immune cells contribute to both secondary brain injury and repair following intracerebral hemorrhage (ICH). However, the signaling pathways governing initial inflammatory and subsequent reparative myeloid programs in living patients ...