Study of the effect of sFRP1 protein on molecules involved in the regulation of DNA methylation in CML cell line [0.03%]
sFRP1蛋白对CML细胞系中DNA甲基化调控相关分子的影响研究
Nazli Demirkiran,Bengusu Aydin,Melek Pehlivan et al.
Nazli Demirkiran et al.
Wnt-signaling pathway plays a crucial role in the pathogenesis and progression of Chronic Myeloid Leukemia (CML). sFRP1 is involved in the suppression of the Wnt-signaling pathway and has been shown to be epigenetically silenced by promoter...
Recent developments in targeting breast cancer stem cells (BCSCs): a descriptive review of therapeutic strategies and emerging therapies [0.03%]
针对乳腺癌干细胞(BCSC)的靶向治疗新进展:治疗策略和新兴疗法的描述性综述
Khubaib Ali,Muhammad Nabeel,Fatima Mohsin et al.
Khubaib Ali et al.
Despite recent advancements in the diagnosis and treatment of breast cancer (BC), patient outcomes in terms of survival, recurrence, and disease progression remain suboptimal. A significant factor contributing to these challenges is the cel...
Coadministration of doxorubicin with vitamin D3, Lactobacillus acidophilus, and Lactobacillus casei in the 4T1 mouse model of breast cancer: anticancer and enteroprotective effects [0.03%]
维生素D3、嗜酸乳杆菌和干酪乳杆菌与阿霉素联用治疗小鼠乳腺癌的抗肿瘤及肠保护作用
Mohammad Ali Mirzadeh,Majid Eslami,Ali Ghanbari et al.
Mohammad Ali Mirzadeh et al.
The use of doxorubicin (Dox) in the treatment of breast cancer negatively affects the intestines and other tissues. Many studies have proven that probiotics and vitamin D3 have antitumor and intestinal tissue-protecting properties. To achie...
Increased V-ATPase activity can lead to chemo-resistance in oral squamous cell carcinoma via autophagy induction: new insights [0.03%]
V型ATP酶活性增强可通过诱导自噬导致口腔鳞状细胞癌化疗耐药性：新认识
Ahmadreza Lagzian,Marziye Askari,Melika Sadat Haeri et al.
Ahmadreza Lagzian et al.
Oral squamous cell carcinoma (OSCC) is a cancer type with a high rate of recurrence and a poor prognosis. Tumor chemo-resistance remains an issue for OSCC patients despite the availability of multimodal therapy options, which causes an incr...
Immunomodulatory effects of Diospyros peregrina fruit preparation (DFP) in non-small cell lung cancer (NSCLC) by utilizing dendritic cell-mediated antigen presentation and T helper (TH) cell differentiation [0.03%]
利用树突状细胞介导的抗原呈递和T辅助（TH）细胞分化研究无花果 Diospyros peregrina果实制剂（DFP）对非小细胞肺癌（NSCLC）免疫调节作用
Nawaneetan Sriraman,Ankita Sarkar,Sohom Naskar et al.
Nawaneetan Sriraman et al.
Diospyros peregrina is a dioecious plant which is native to India. It belongs to the family of Ebenaceae and is extensively used to treat various ailments, such as leucorrhoea and other uterine-related problems. Though few studies have been...
Probiotic-derived silver nanoparticles target mTOR/MMP-9/BCL-2/dependent AMPK activation for hepatic cancer treatment [0.03%]
益生菌衍生的银纳米粒子靶向mTOR/MMP-9/BCL-2/依赖性AMPK激活以治疗肝癌
Alaa Elmetwalli,Mohamed O Abdel-Monem,Ali H El-Far et al.
Alaa Elmetwalli et al.
Recent advances in nanotechnology have offered novel ways to combat cancer. By utilizing the reducing capabilities of Lactobacillus acidophilus, silver nanoparticles (AgNPs) are synthesized. The anti-cancer properties of AgNPs have been dem...
Citalopram, an antipsychotic agent, induces G1/G0 phase cell cycle arrest and promotes apoptosis in human laryngeal carcinoma HEP-2 cells [0.03%]
西酞普兰通过诱导G1/G0期细胞周期停滞和促进凋亡抑制人喉癌HEP-2细胞生长
Mohammed Salama,Abeer Ali,Fawziya A R Ibrahim et al.
Mohammed Salama et al.
Human laryngeal squamous carcinoma (LSCC) is a common malignant tumor in the head and neck. Despite the recently developed therapies for the treatment of LSCC, patients' overall survival rate still did not enhance remarkably; this highlight...
Unlocking the potential: phenylboronic acid as a nuclear-targeting boron agent for neutron capture therapy [0.03%]
潜在的开启作用：苯基硼酸作为中子捕获治疗的核靶向硼剂
Jiejian Chen,Yonghao Li,Xiaoning Gan et al.
Jiejian Chen et al.
It has been proposed that boron neutron capture therapy (BNCT) holds promise as a treatment modality for melanoma. However, the effectiveness of boron agents in delivery remains a critical issue to be addressed for BNCT. To this end, phenyl...
Regulation of hippo signaling mediated apoptosis by Rauvolfia tetraphylla in triple-negative breast cancer [0.03%]
朱氏四叶草调控hippo信号介导的三阴性乳腺癌细胞凋亡作用研究
B Balavaishnavi,M Kamaraj,T G Nithya et al.
B Balavaishnavi et al.
Rauvolfia tetraphylla is an essential medicinal plant that has been widely used in traditional medicine for various disease treatments. However, the tumor suppressor activity of R. tetraphylla and its phytocompounds were not explored agains...
Investigating the correlation between prominent viruses and hematological malignancies: a literature review [0.03%]
著名病毒与血液系统恶性肿瘤关联性研究——文献综述
Arian Haghtalab,Milad Hejazi,Naeem Goharnia et al.
Arian Haghtalab et al.
Extensive research has been conducted on the correlation between viral infections and hematological cancers ever since the identification of the Rous Sarcoma Virus as a cancer-causing agent. Numerous viruses, such as the Epstein-Barr virus,...