Correction to: Gingerol and/or sorafenib attenuates the DAB-induced HCC and hepatic portal vein dilatation via ATG4/CASP3 and COIIV/COX-2/NF-κB expression [0.03%]
姜酚和/或索拉非尼通过调节ATG4/CASP3和COIVV/COX-2/NF-κB表达减轻DAB致小鼠肝细胞癌及门脉扩张的机制研究纠正版
Afrah Fatthi Salama,Ali H El-Far,Esraa Ali Anbar et al.
Afrah Fatthi Salama et al.
FTO promotes gastric cancer progression by modulating MAP4K4 expression via demethylation in an m6A-dependent manner [0.03%]
FTO通过m6A依赖性的去甲基化调节MAP4K4表达从而促进胃癌进展
Zhe Yin,Xiong Guo,Xiaolong Liang et al.
Zhe Yin et al.
Gastric cancer (GC) is a serious malignant tumour with a high mortality rate and a poor prognosis. Recently, emerging evidence has suggested that N6-methyladenosine (m6A) modification plays a crucial regulatory role in cancer progression. H...
Chlordiazepoxide against signalling, receptor and regulatory proteins of breast cancer: a structure-based in-silico approach [0.03%]
基于结构的计算方法研究氯地西泮与乳腺癌信号传导、受体和调节蛋白的相互作用
Ahad Amer Alsaiari,Amal F Gharib,Maha Mahfouz Bakhuraysah et al.
Ahad Amer Alsaiari et al.
Among the most prevalent forms of cancer are breast, lung, colon-rectum, and prostate cancers, and breast cancer is a major global health challenge, contributing to 2.26 million cases with approximately 685,000 deaths worldwide in 2020 alon...
Identification of small molecule inhibitors against Lin28/let-7 to suppress tumor progression and its alleviation role in LIN28-dependent glucose metabolism [0.03%]
用于抑制肿瘤发展的Lin28/let-7的小分子抑制剂鉴定及其在LIN28依赖性葡萄糖代谢缓解作用中的作用
Rachanaa Raja,Rajamanikandan Sundararaj,Ruckmani Kandasamy
Rachanaa Raja
The reciprocal suppression of an RNA-binding protein LIN28 (human abnormal cell lineage 28) and miRNA Let-7 (Lethal 7) is considered to have a prime role in hepatocellular carcinoma (HCC). Though targeting this inhibition interaction is eff...
Hanyun Liang,Xin Zheng,Xiao Zhang et al.
Hanyun Liang et al.
Chromatin remodeling is a critical step in the DNA damage response, and the ATP-dependent chromatin remodelers are a group of epigenetic regulators that alter nucleosome assembly and regulate transcription factor accessibility to DNA, preve...
Chengu Niu,Jing Zhang,Patrick I Okolo rd
Chengu Niu
Liver cancer currently represents the leading cause of cancer-related death worldwide. The majority of liver cancer arises in the context of chronic inflammation and cirrhosis. Surgery, radiation therapy, and chemotherapy have been the guid...
Exploring the immunomodulatory potential of Brahmi (Bacopa monnieri) in the treatment of invasive ductal carcinoma [0.03%]
探讨 Bacopa monnieri 在治疗侵袭性导管癌中的免疫调节潜力
Sohini Roy,Geetha Shanmugam,Sudeshna Rakshit et al.
Sohini Roy et al.
Bacopa monnieri (L) Wettst, commonly known as Brahmi, stands as a medicinal plant integral to India's traditional medical system, Ayurveda, where it is recognized as a "medhya rasayana"-a botanical entity believed to enhance intellect and m...
Dual function of activated PPARγ by ligands on tumor growth and immunotherapy [0.03%]
配体激活的PPARγ的双重作用对肿瘤生长和免疫治疗的影响
Mingjun Chen,Huijie Wang,Qian Cui et al.
Mingjun Chen et al.
As one of the peroxisome-proliferator-activated receptors (PPARs) members, PPARγ is a ligand binding and activated nuclear hormone receptor, which is an important regulator in metabolism, proliferation, tumor progression, and immune respon...
A novel α,β-unsaturated ketone inhibits leukemia cell growth as PARP1 inhibitor [0.03%]
一种新型α,β-不饱和酮通过抑制PARP1抑制白血病细胞增殖
Weijia Zhao,Min Mo,Jia Yu et al.
Weijia Zhao et al.
Leukemia is a malignant disease of the hematopoietic system, in which clonal leukemia cells accumulate and inhibit normal hematopoiesis in the bone marrow and other hematopoietic tissues as a result of uncontrolled proliferation and impaire...
Combination of IFN-gamma with STING agonist and PD-1 immune checkpoint blockade: a potential immunotherapy for gastric cancer [0.03%]
IFN-γ联合STING激动剂和PD-1免疫检查点阻断用于胃癌免疫治疗的潜力研究
Shahnaz Hosseinzadeh,Mahsa Imani,Farhad Pourfarzi et al.
Shahnaz Hosseinzadeh et al.
Suppression of the cGAS-STING pathway is an immune escape mechanism in cancer cells. The critical role of this pathway in gastric cancer (GC) is not fully understood. Herein, we evaluated the effect of the interferon-gamma (IFN-gamma), STIN...