NLRX1: a key regulator in mitochondrial respiration and colorectal cancer progression [0.03%]
NLRX1：线粒体呼吸和结直肠癌发生发展中的一把关键钥匙
Yaxin Ding,Wenjie Sun,Mingwei Han et al.
Yaxin Ding et al.
Colorectal cancer (CRC) is a prevalent and aggressive malignancy with high mortality rates and significant risks to human well-being. Population-wide screening for tumor suppressor genes and oncogenes shows promise for reducing the incidenc...
In silico and network pharmacology analysis of fucosterol: a potent anticancer bioactive compound against HCC [0.03%]
基于计算机和网络药理学的糖甾醇抗HCC活性成分分析
Kajal Singh,Pradeep Kumar,Amit Kumar Singh et al.
Kajal Singh et al.
The Fucaceae family of marine brown algae includes Ascophyllum nodosum. Fucosterol (FSL) is a unique bioactive component that was identified through GC-MS analysis of the hydroalcoholic extract of A. nodosum. Fucosterol's mechanism of actio...
Retraction Note: Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway [0.03%]
撤回 notice: 通过抑制 pi3k/akt信号通路促进口腔鳞状细胞癌凋亡和增殖的pole2基因沉默促进口腔鳞状细胞癌凋亡和增殖
Shengyou Ge,Kexin Wang,Yuxiang Meng et al.
Shengyou Ge et al.
Retraction of Publication
Medical oncology (Northwood, London, England). 2024 Apr 26;41(6):129. DOI:10.1007/s12032-024-02377-7 2024
Role of the STING pathway in myeloid neoplasms: a prospero-registered systematic review of principal hurdles of STING on the road to the clinical practice [0.03%]
STING通路在髓系肿瘤中的作用：一项关于STING通路进入临床应用主要障碍的系统评价和 meta 分析（PRO注册）
Leticia Rodrigues Sampaio,Ricardo Dyllan Barbosa Dias,João Vitor Caetano Goes et al.
Leticia Rodrigues Sampaio et al.
Myeloid neoplasms are a group of bone marrow diseases distinguished by disruptions in the molecular pathways that regulate the balance between hematopoietic stem cell (HSC) self-renewal and the generation of specialized cells. Cytokines and...
A new vision of the efficacy of both CAR-NK and CAR-T cells in treating cancers and autoimmune diseases [0.03%]
CAR-NK细胞和CAR-T细胞在癌症和自身免疫性疾病治疗中的有效性的新见解
Salim Hussein Hassan,Mohammad Y Alshahrani,Raed Obaid Saleh et al.
Salim Hussein Hassan et al.
Chimeric Antigen Receptor (CAR) based therapies are becoming increasingly important in treating patients. CAR-T cells have been shown to be highly effective in the treatment of hematological malignancies. However, harmful therapeutic barrie...
Afrasyab Khan,Yu Huo,Yilei Guo et al.
Afrasyab Khan et al.
Ferroptosis is a form of intracellular iron-dependent cell death that differs from necrosis, autophagy and apoptosis. Intracellular iron mediates Fenton reaction resulting in lipid peroxidation production, which in turn promotes cell death....
N-methyl-D-aspartate receptors and thymoquinone induce apoptosis and alteration in mitochondria in colorectal cancer cells [0.03%]
N-甲基-D-天冬氨酸受体和伞形公英烃诱发结直肠癌细胞的凋亡及对线粒体的影响
Ferhat Sirinyildiz,Simge Unay
Ferhat Sirinyildiz
Colon cancer is on the rise in both men and women. In addition to traditional treatment methods, herbal treatments from complementary and alternative medicine are actively followed. Naturally derived from plants, thymoquinone (TQ) has drawn...
Comprehensive review of the repositioning of non-oncologic drugs for cancer immunotherapy [0.03%]
非抗肿瘤药物用于癌症免疫治疗的再定位综合述评
Abdur Rauf,Payal B Joshi,Ahmed Olatunde et al.
Abdur Rauf et al.
Drug repositioning or repurposing has gained worldwide attention as a plausible way to search for novel molecules for the treatment of particular diseases or disorders. Drug repurposing essentially refers to uncovering approved or failed co...
Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives [0.03%]
姜黄酚抗肿瘤的潜力：当前趋势和未来展望
Alborz Soroush,Siavash Pourhossein,Dorrin Hosseingholizadeh et al.
Alborz Soroush et al.
Plant-derived immunomodulators and antitumor factors have appealed lots of attention from natural product scientists for their efficiency and safety and their important contribution to well-designed targeted drug action and delivery mechani...
Challenges and strategies in relation to effective CAR-T cell immunotherapy for solid tumors [0.03%]
有关有效CAR-T细胞免疫治疗实体肿瘤的挑战与策略
Guangxun Yuan,Mengke Ye,Yixi Zhang et al.
Guangxun Yuan et al.
Chimeric Antigen Receptor T cell (CAR-T) therapy has revolutionized cancer treatment, but its application to solid tumors is limited. CAR-T cells have poor incapability of entering, surviving, proliferating, and finally exerting function in...