The role of IGFBP-3 in tumor development and progression: enlightenment for diagnosis and treatment [0.03%]
IGFBP-3在肿瘤发生发展中的作用及对诊断和治疗的启示
Yudi Wang,He Zhang,Xuehua Zhang et al.
Yudi Wang et al.
IGFBP-3 is aberrantly expressed in many tumor types, and its serum and tumor tissue levels provide auxiliary information for assessing the degree of tumor malignancy and patient prognosis, making it a potential therapeutic target for human ...
Altering biomolecular condensates as a potential mechanism that mediates cannabidiol effect on glioblastoma [0.03%]
通过改变生物分子凝集物作为大麻二酚对胶质母细胞瘤作用的潜在机制
Lei P Wang,Pablo Shimaoka Chagas,Évila Lopes Salles et al.
Lei P Wang et al.
Glioblastoma (GBM) is an extremely aggressive primary brain tumor with poor prognosis, short survival time post-diagnosis and high recurrence. Currently, no cure for GBM exists. The identification of an effective therapeutic modality for GB...
Standardized phase angle: relationship with functionality, muscle mass and postoperative outcomes in surgical cancer patients [0.03%]
标准化相角：与功能、肌肉质量及手术癌症患者的术后结局的关系
Jéssica Härter,Silvana Paiva Orlandi,Renata Moraes Bielemann et al.
Jéssica Härter et al.
To evaluate the association of standardized phase angle (SPA) with nutritional status, functional parameters, and postoperative outcomes in surgical cancer patients. This prospective study includes 59 cancer patients from Pelotas (Brazil) a...
The role of radiation therapy in locally advanced rectal cancer [In regard to primary surgery followed by selective chemoradiotherapy versus preoperative chemoradiotherapy followed by surgery for locally advanced rectal cancer: a randomized clinical trial] [0.03%]
局部晚期直肠癌放射治疗的作用[关于局部晚期直肠癌初次手术联合选择性化学放射治疗与术前化学放射治疗联合手术的随机临床试验]
Francesca De Felice
Francesca De Felice
Randomized Controlled Trial
Medical oncology (Northwood, London, England). 2024 May 5;41(6):136. DOI:10.1007/s12032-024-02371-z 2024
Glucagon-like peptide-1 analogs activate AMP kinase leading to reversal of the Warburg metabolic switch in breast cancer cells [0.03%]
肠促胰岛素类似物通过活化AMPK逆转乳腺癌细胞的瓦博格效应
Hagai Ligumsky,Sharon Amir,Tamar Arbel Rubinstein et al.
Hagai Ligumsky et al.
Breast cancer (BC) is associated with type 2 diabetes mellitus (T2DM) and obesity. Glucagon-like peptide (GLP)-1 regulates post-prandial insulin secretion, satiety, and gastric emptying. Several GLP-1 analogs have been FDA-approved for the ...
CLIP170 inhibits the metastasis and EMT of papillary thyroid cancer through the TGF-β pathway [0.03%]
CLIP170通过TGF-β信号通路抑制乳头状甲状腺癌的转移和上皮间质转化
Binyuan Ma,Yaxin Xu,Hongwei Gao et al.
Binyuan Ma et al.
Metastasis poses a significant challenge in combating tumors. Even in papillary thyroid cancer (PTC), which typically exhibits a favorable prognosis, high recurrence rates are attributed to metastasis. Cytoplasmic linker protein 170 (CLIP17...
Lung adenocarcinomas without driver genes converge to common adaptive strategies through diverse genetic, epigenetic, and niche construction evolutionary pathways [0.03%]
无驱动基因的肺腺癌通过多种遗传、表观遗传和生态位构建进化途径收敛到常见的适应性策略
Robert A Gatenby,Kimberly A Luddy,Jamie K Teer et al.
Robert A Gatenby et al.
Somatic evolution selects cancer cell phenotypes that maximize survival and proliferation in dynamic environments. Although cancer cells are molecularly heterogeneous, we hypothesized convergent adaptive strategies to common host selection ...
A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways [0.03%]
植物成分在肝癌预防和治疗中的全面回顾：分子信号通路的目标见解
Md Rezaul Islam,Abdur Rauf,Shopnil Alash et al.
Md Rezaul Islam et al.
Primary liver cancer is a type of cancer that develops in the liver. Hepatocellular carcinoma is a primary liver cancer that usually affects adults. Liver cancer is a fatal global condition that affects millions of people worldwide. Despite...
Anchi Sun,Zhiwei Xing,Rongrong Lv et al.
Anchi Sun et al.
Head and neck cancer accounts for about one-fifth of all malignant tumors, and the incidence is increasing year by year. The overall mortality rate was high and the 5-year survival rate was low. At present, the combination of surgery, radio...
Drug-loaded polymer-coated silver nanoparticles for lung cancer theranostics [0.03%]
用于肺癌诊疗的载药聚合物包覆银纳米颗粒
Ranjita Misra,Subhenjit Hazra,Suraiya Saleem et al.
Ranjita Misra et al.
Lung cancer is the leading cause of death in cancer across the globe. To minimize these deaths, the replacement of traditional chemotherapy with novel strategies is significant. We have developed a nanotheranostic approach using silver nano...