Dipti Patil,Swapnil Raut,Mitesh Joshi et al.
Dipti Patil et al.
Despite decades of basic and clinical research and trials of promising new therapies, cancer remains a major cause of morbidity and mortality due to the emergence of drug resistance to anticancer drugs. These resistance events have a very w...
Therapeutic targeting of TNIK in papillary thyroid carcinoma: a novel approach for tumor growth suppression [0.03%]
嗜酸细胞型甲状腺癌的治疗靶点TNIK：一种抑制肿瘤生长的新方法
Ruqian Zhang,Yongbo Yu,Yeran Yang et al.
Ruqian Zhang et al.
Papillary thyroid carcinoma (PTC) is a common endocrine malignancy. The pathology of PTC is far from clear. As a kinase that can be targeted, the role of TNIK in PTC has not been investigated. This study was focused on the effects and molec...
Chunyu Wu,Lvyuan Li,Qiling Tang et al.
Chunyu Wu et al.
RNA modification has garnered increasing attention in recent years due to its pivotal role in tumorigenesis and immune surveillance. N6-methyladenosine (m6A) modification is the most prevalent RNA modification, which can affect the expressi...
Insights into Nimbolide molecular crosstalk and its anticancer properties [0.03%]
关于Nimbolide分子交叉对话及其抗癌性质的见解
Shabnum Shaheen,Sana Khalid,Khadija Aaliya et al.
Shabnum Shaheen et al.
Nimbolide, one of the main ingredients constituent of Azadirachta indica (neem) leaf extract, has garnered attention for its potential as an anticancer agent. Its efficacy against various cancers and chemopreventive action has been demonstr...
Common skin cancers and their association with other non-cutaneous primary malignancies: a review of the literature [0.03%]
常见皮肤癌与其它非皮肤原发性恶性肿瘤相关性的文献综述
Lindsay Holic
Lindsay Holic
It has long been recognized that a history of skin cancer puts one at risk for additional primary skin cancers. However, more variable data exists for the risk of developing a non-cutaneous primary cancer following a diagnosis of skin cance...
Pharmacokinetic studies, molecular docking, and molecular dynamics simulations of phytochemicals from Morus alba: a multi receptor approach for potential therapeutic agents in colorectal cancer [0.03%]
药用植物桑白皮中活性化合物的药代动力学研究、分子对接及分子动力学模拟：一种潜在治疗结直肠癌药物的多受体方法
B Stany,Shatakshi Mishra,K V Bhaskara Rao
B Stany
This study explores the therapeutic potential of phytochemicals derived from Morus alba for colorectal cancer (CRC) treatment. Colorectal cancer is a global health concern with increasing mortality rates, necessitating innovative strategies...
IL-6 regulates epithelial ovarian cancer EMT, invasion, and metastasis by modulating Let-7c and miR-200c through the STAT3/HIF-1α pathway [0.03%]
IL-6通过STAT3/HIF-1α通路调节Let-7c和miR-200c从而调控上皮卵巢癌EMT、侵袭及转移
Qiao Yun Guo,Jiang Nan Song,Yu Meng Chen et al.
Qiao Yun Guo et al.
Interleukin-6 (IL-6) and hypoxia-inducible factor-1α (HIF-1α) play important roles in epithelial-mesenchymal transformation (EMT) and tumor development. Previous studies have demonstrated that IL-6 promotes EMT, invasion, and metastasis i...
Rhein suppresses esophageal cancer development by regulating cell cycle through DNMT3B gene [0.03%]
Rhien通过DNMT3B基因调控细胞周期来抑制食管癌的发生发展
Cheng Li,Jingjing Yu,Ying Feng et al.
Cheng Li et al.
The mechanism by which DNMT3B facilitates esophageal cancer (ESCA) progression is currently unknown, despite its association with adverse prognoses in several cancer types. To investigate the potential therapeutic effects of the Chinese her...
Ethanolic extract of Euphorbia royleana Boiss. reduces metastasis of breast cancer cells and inhibits tumor progression in vivo [0.03%]
瑞诺亚灌木的乙醇提取物可减少乳腺癌细胞转移并抑制体内肿瘤发展
Sheereen Gull,Fareeda Tasneem,Ishtiaq Ahmed et al.
Sheereen Gull et al.
Metastasis is the most devastating attribute of breast cancer (BC) that leads to high mortality. It is a complex process of tumor cell migration, invasion, and angiogenesis. In this study, we evaluated the effect of ERA on BC metastasis and...