Emerging Anti-Cancer and Repurposed Therapies for Overcoming Multidrug Resistance in Lung Cancer [0.03%]
用于克服肺癌多药耐药性的新兴抗肿瘤和再定位疗法
Nilay Solanki,Pratham Shah,Sargam Kewalramani et al.
Nilay Solanki et al.
Multidrug resistance (MDR) still constitutes a significant barrier to the effective treatment of lung cancer and makes a significant contribution to the poor clinical results. MDR is explained by a set of mechanisms; increase of drug efflux...
Psychosocial experiences of cancer patients across the COVID-19 era: Lasting implications for oncology [0.03%]
新冠肺炎疫情期间癌症患者的身心健康体验及对肿瘤学的持久影响
Ozgur Tanriverdi,Ahmet Ozcan Kaygisiz,Turan Karaoglu et al.
Ozgur Tanriverdi et al.
Engineered nanoparticles for endocrine tumor targeting, current progress and future outlook [0.03%]
内分泌肿瘤靶向工程纳米颗粒的最新进展及未来展望
Maryam Aftab,Zubair Ahmed,Muneeb Ullah et al.
Maryam Aftab et al.
Endocrine tumors are hormone-secreting tumors that pose significant challenges for diagnosis and treatment due to their complex biological processes, delayed detection, and poor response to existing therapies. Despite advancements in imagin...
ECSCR functions as a potential tumor suppressor in breast cancer cells [0.03%]
ECSCR作为乳腺癌细胞中的一种潜在的抑癌基因的功能研究
Sen Lian,Yi Huang,Ling Liang et al.
Sen Lian et al.
Breast cancer is the most commonly diagnosed malignancy among women worldwide. Triple-negative breast cancer (TNBC), a particularly aggressive subtype, is unresponsive to endocrine and targeted therapies. It is characterized by high rates o...
Run Shi,Yang Liu,RuiXue Yu
Run Shi
Collagen prolyl 4-hydroxylase (C-P4H) is a critical enzyme involved in collagen biosynthesis, mediating the hydroxylation of proline residues to ensure the stability of collagen and its integration into the extracellular matrix (ECM). Withi...
Combined inhibition of insulin growth factor 1 receptor and autophagy prevents colorectal cancer metastasis [0.03%]
胰岛素样生长因子-1受体和自噬联合抑制可防止结直肠癌转移
Eglal Mahgoub,Khuloud Bajbouj,Samrein Ahmed et al.
Eglal Mahgoub et al.
The role of Insulin-like growth factor 1 (IGF-1) in promoting cancer proliferation has been identified, yet its potential role in metastasis has not been fully elucidated. Autophagy plays a pivotal, yet controversial, role in regulating can...
Exosomal non-coding RNAs as emerging drivers of immune dysregulation in melanoma [0.03%]
外泌体非编码RNA在黑色素瘤免疫失调中的新兴驱动作用
Bahaa Ibrahim Saeed,Wesam R Kadhum,Muhammad Ikram Ullah et al.
Bahaa Ibrahim Saeed et al.
Melanoma is a type of skin cancer that starts in melanocytes. It is estimated to increase by 2050 based on prediction studies. Exosomes have been identified as crucial intracellular mediators by carrying the donor-derived cargoes from strom...
Lipidomics analysis of ceramidase inhibition-induced intracellular lipid profile changes in lung cancer cells [0.03%]
关于鞘氨醇脂酶抑制引起的肺癌细胞内脂质体变化的脂质组学分析
Hüseyin İzgördü,Canan Vejselova Sezer,Gökhan Kuş et al.
Hüseyin İzgördü et al.
Lung cancer is among the most prevalent types of cancer globally and in Türkiye. Basically, lung cancer is divided into 2 different types, of which non-small cell lung cancer (NSCLC) accounts for about 85% of cases. With the elucidation of...
Nanovaccines in hepatocellular carcinoma: a new frontier in cancer immunotherapy [0.03%]
纳米疫苗在肝细胞癌中的应用：癌症免疫治疗的新前沿
Afreen Usmani,Mohd Aftab Siddiqui,Anuradha Mishra et al.
Afreen Usmani et al.
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, underscoring the urgent need for novel therapeutic approaches beyond standard treatments. Nanovaccines are a revolutionary platform in cancer immu...
Sai Prasath,S P Harsha,Anusha Mruthyunjaya Swamy et al.
Sai Prasath et al.
Glucocorticoids are cornerstone agents in oncology due to their potent anti-inflammatory, immunosuppressive, and antitumor properties. Glucocorticoids exert direct cytotoxic effects in hematologic malignancies such as lymphomas, acute lymph...