Exploring the Potential of Essential Oil from Plectranthus amboinicus Leaves against Breast Cancer: In vitro and In silico Analysis [0.03%]
探討佩克特兰瑟 Amboinicus 叶子精油對乳腺癌的潛在作用：體外和計算分析
Khushi Gupta,Pranay Gautre,Avadh Biharee et al.
Khushi Gupta et al.
Plectranthus amboinicus leaves were subjected to hydrodistillation to obtain essential oil (EO). Phytochemical analysis using gas chromatography-mass spectrometry revealed a diverse range of compounds in the EO, with p-cymen-4-ol (18.57%) e...
Venetoclax with decitabine or azacitidine in relapsed or refractory acute myeloid leukemia [0.03%]
在复发或难治性急性髓系白血病患者中进行的维奈托克联合地西他滨或阿扎胞苷的研究
Ian M Bouligny,Graeme Murray,Michael Doyel et al.
Ian M Bouligny et al.
Relapsed or refractory acute myeloid leukemia (AML) is associated with poor outcomes and resistance to therapy. The addition of venetoclax, a BCL-2 antagonist, to lower-intensity therapies results in improved survival in the first-line sett...
Correction to: Exploring the advances of single‑cell RNA sequencing in thyroid cancer: a narrative review [0.03%]
更正：探索甲状腺癌中单细胞RNA测序的进步的叙述性回顾
Joecelyn Kirani Tan,Wireko Andrew Awuah,Sakshi Roy et al.
Joecelyn Kirani Tan et al.
TRIM29 modulates proteins involved in PTEN/AKT/mTOR and JAK2/STAT3 signaling pathway and suppresses the progression of hepatocellular carcinoma [0.03%]
TRIM29调节与PTEN/AKT/mTOR和JAK2/STAT3信号通路相关的蛋白质并抑制肝细胞癌的进展
Yu-Ting Yin,Lu Shi,Chun Wu et al.
Yu-Ting Yin et al.
Tripartite motif-containing 29 (TRIM29), also known as the ataxia telangiectasia group D-complementing (ATDC) gene, has been reported to play an oncogenic or tumor suppressive role in developing different tumors. So far, its expression and ...
Evaluation of TRIM63 RNA in situ hybridization (RNA-ISH) as a potential biomarker for alveolar soft-part sarcoma (ASPS) [0.03%]
TRIM63 RNA原位杂交(RNA-ISH)作为肺软部部分肉瘤(ASPS)潜在生物标志物的评估
Alexander S Taylor,Rahul Mannan,Liron Pantanowitz et al.
Alexander S Taylor et al.
Alveolar soft-part sarcoma (ASPS) is a rare soft tissue tumor with a broad morphologic differential diagnosis. While histology and immunohistochemistry can be suggestive, diagnosis often requires exclusion of other entities followed by conf...
Estrogen-related receptor alpha (ERRα) promotes the migration, invasion and angiogenesis of breast cancer stem cell-like cells [0.03%]
雌激素相关受体α(ERRα)促进乳腺癌干细胞类细胞的迁移、侵袭和血管生成
Kartik Muduli,Jagannath Pradhan,Monica Prusty et al.
Kartik Muduli et al.
Breast cancer progression, metastasis and recurrence are largely driven by breast cancer stem cells (BCSCs), which constitute a subset of tumor cells exhibiting stem cell characteristics. In this study, we evaluated the role of estrogen-rel...
Insights into lenvatinib resistance: mechanisms, potential biomarkers, and strategies to enhance sensitivity [0.03%]
关于乐伐替尼耐药性的见解：机制、潜在生物标志物及提高敏感性的策略
Qiang You,Rong Li,Jia Yao et al.
Qiang You et al.
Lenvatinib is a multitargeted tyrosine kinase inhibitor capable of promoting apoptosis, suppressing angiogenesis, inhibiting tumor cell proliferation, and modulating the immune response. In multiple cancer types, lenvatinib has presented ma...
Clinical significance of blocking novel immune checkpoint B7-H4 in urothelial carcinoma of bladder as a potential therapeutic target [0.03%]
膀胱尿路上皮癌中新型免疫检查点B7-H4的阻断作为潜在治疗靶点的临床意义
David Raja,Aishwarya Singh,Santosh Kurra et al.
David Raja et al.
Urothelial Carcinoma of Bladder is complex disease with high mortality and recurrence rates. Current standard regimes have exhibited anti-tumor activity but still, a proportion of patients are non-responsive or in-eligible to receive such t...
Advancements in biosensors for cancer detection: revolutionizing diagnostics [0.03%]
癌症检测生物传感器的进展：诊断革命
Syed Khalid Mustafa,Mohd Farhan Khan,Mehak Sagheer et al.
Syed Khalid Mustafa et al.
Cancer stands as the reigning champion of life-threatening diseases, casting a shadow with the highest global mortality rate. Unleashing the power of early cancer treatment is a vital weapon in the battle for efficient and positive outcomes...
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway [0.03%]
CRP通过初级纤毛的上调和Hedgehog信号通路的抑制来抑制OPCs的成骨分化
Jie Xu,Xiangmei Wu,Huifang Zhu et al.
Jie Xu et al.
Inflammation disrupts bone metabolism and leads to bone damage. C-reactive protein (CRP) is a typical inflammation marker. Although CRP measurement has been conducted for many decades, how osteoblastic differentiation influences molecular m...