G Proteins-Associated Dose-Dependent Effects of Oxytocin on Oxytocin Neuronal Activity and Astrocytic Plasticity of the Supraoptic Nucleus [0.03%]
催产素剂量依赖性效应作用于室管膜下区神经干细胞增殖和分化的影响及机制研究摘要
Xiao-Yu Liu,Shuo Ling,Yang Liu et al.
Xiao-Yu Liu et al.
Dose-dependent neuromodulation has been well established; however, the molecular mechanisms underlying astrocytic involvement in this process remain largely unexplored. Using the autoregulation of supraoptic oxytocin (OT) neurons (OTNs) as ...
Genetically Elevated Neutrophil Count Is Associated with Poor Outcome Following Ischemic Stroke: A Mendelian Randomization Study [0.03%]
缺血性脑卒中后较高中性粒细胞计数与不良结局相关：一项孟德尔随机化研究
Mengmeng Wang,Iyas Daghlas,Liping Cao et al.
Mengmeng Wang et al.
The aim of this study was to investigate the association between genetically proxied white blood cell (WBC) subtype counts and functional outcome following ischemic stroke. Genetic proxies for counts of neutrophils, lymphocytes, monocytes, ...
Osteogenesis Imperfecta: A Look into the Cerebellum of the Brtl Murine Model [0.03%]
脆骨病：BrTL小鼠模型 cerebellum 的研究 взгляд в cerebellum модели мыши Brtl с остеогенной не完整性不足，已知信息中并未给出完整的中文翻译结果。根据提供的英文标题内容，可以尝试进行概括性描述：
"脆骨病的神经学研究：探索BrTL型鼠模型小脑的结构与功能"
这只是一个对原题目的理解与推测，并非官方或直接的翻译。如果有特定医学背景或更准确的翻译需求，请提供更多信息以便给出最恰当的回答。
Fabrizio De Luca,Roberta Besio,Emma Lugli et al.
Fabrizio De Luca et al.
Osteogenesis imperfecta (OI), also known as brittle bone disease, is a rare congenital connective tissue disorder linked to collagen I defects, commonly known for its skeletal implications. However, collagen fibers play several key roles al...
Mammalian Sterile 20-Like Kinase 2 Knockdown Alleviates Neuropathic Pain in Rats by Mitochondrial Protection [0.03%]
哺乳动物Sterile 20样激酶2敲低通过线粒体保护缓解大鼠神经病理性疼痛
Qing Zeng,Bei-Xu Huang,Chang Liu et al.
Qing Zeng et al.
Neuropathic pain (NP) is a common chronic pain that lacks durable, mechanism-based therapies, making it a global health concern. Mitochondrial protection is essential to alleviate oxidative stress and maintain normal energy metabolism, play...
The Role of Glial Fibrillary Acidic Protein in the Neuropathology of Alzheimer's Disease and Its Potential as a Blood Biomarker for Early Diagnosis and Progression [0.03%]
胶质纤维酸性蛋白在阿尔茨海默病神经病理中的作用及其作为早期诊断和病情进展血液生物标志物的潜力
Ekanayaka M S Bandara,Prita R Asih,Steve Pedrini et al.
Ekanayaka M S Bandara et al.
Alzheimer's disease (AD) is a neurodegenerative disease characterised by neuropathological hallmarks, including extracellular amyloid plaques and neurofibrillary tangles. The disease is clinically defined by cognitive dysfunction, including...
Repeated Clozapine Administration Causes Extensive Changes to the Expression of Coding and Non-coding RNAs, Including miR-124, in the Mouse Frontal Cortex [0.03%]
反复克洛扎平给药可引起小鼠前额叶皮层蛋白编码和非编码RNA（包括miR-124）表达的广泛变化
Rabha Mussa Younis,Dalia Y Al Saeedy,Mikhail G Dozmorov et al.
Rabha Mussa Younis et al.
Clozapine is arguably the most effective antipsychotic drug for the treatment of schizophrenia, but the mechanisms underlying its efficacy are poorly understood. Therefore, we perform deep RNA sequencing to test for differential transcripti...
Novel Insights into Schizophrenia Treatment: Comprehensive Analysis Unveiling FGFR1 as a Promising Druggable Gene [0.03%]
schizophrenia治疗的新见解：全面分析揭示FGFR1作为有前景的可成药基因
Kun Lian,Wei Yang,Runxu Yang et al.
Kun Lian et al.
Schizophrenia (SCZ) is a chronic, relapsing mental disorder with a complex and poorly understood etiology. Identifying novel therapeutic targets is essential for advancing treatment options. Druggable genes were sourced from the eQTLGen con...
Melatonin Attenuates Spinal Cord Injury by Regulating Ferroptosis Through the Nrf2/HO-1/GPX4 Pathway [0.03%]
褪黑素通过Nrf2/HO-1/GPX4通路调节铁死亡从而缓解脊髓损伤
Zhengxi Yu,Dingwei Wu,Tengbin Shi et al.
Zhengxi Yu et al.
Spinal cord injury (SCI) is one of the most devastating and catastrophic types of injury, with high rates of mortality and disability. Ferroptosis has become the target of many major incurable human diseases. By inhibiting ferroptosis, mela...
PD-1 Attenuates Neuropathic Pain by Ameliorating NLRP3 Inflammasome-Mediated Microglia Pyroptosis [0.03%]
PD-1通过改善NLRP3炎症小体介导的微胶质细胞焦亡来减轻神经病理性疼痛
Daling Deng,Lulin Ma,Jiwei Shen et al.
Daling Deng et al.
Neuropathic pain lacks effective clinical treatments due to its complex pathogenesis. Growing evidence indicates that programmed cell death receptor-1 (PD-1) plays a vital role in reducing neuropathic pain. Recent studies have also implicat...
Golden Oyster Mushroom Extract Ameliorates Oxidative Stress-Induced Cell Death in Neurons and Scopolamine-Induced Cholinergic System Impairment in Mice [0.03%]
金牡蛎菇提取物改善氧化应激诱导的神经元细胞死亡及东莨菪碱致小鼠胆碱能系统损伤
Ho-Sung Ryu,Sanjay,Sung-Keun Choi et al.
Ho-Sung Ryu et al.
Impaired cholinergic system is an important therapeutic target to develop drugs against Alzheimer's disease (AD), as cholinergic signal transduction is associated with the memory, learning, and behavior of an individual. Acetylcholine (ACh)...