Dual Effect of Melatonin in Fetal Brain: Structural and Cellular Implications in a Rabbit Model of Intrauterine Growth Restriction [0.03%]
褪黑素对胎儿脑的双重作用:在兔宫内生长受限模型中的结构和细胞意义
Laia Guardia-Escote,Yvan Gómez,Mercè Fuentes-Amell et al.
Laia Guardia-Escote et al.
Intrauterine growth restriction (IUGR) is a condition in which the fetus fails to reach its genetic growth potential, often resulting in neurodevelopmental alterations. This study investigates the neuroprotective potential of gestational me...
BDNF Signaling in Glutamatergic Neurons During Long-Term Potentiation (LTP): A Spatio-Temporal Exploration of Events [0.03%]
长期增强作用过程中谷氨酸能神经元的脑源性神经营养因子信号通路:事件时空变化的研究
Krishnakumar Mohandas,Rishikesh Rishikesh,Yadukrishnan Moothedath Balan et al.
Krishnakumar Mohandas et al.
Long-term potentiation (LTP), a cellular mechanism underlying learning and memory, progresses through three stages-initial, early, and late-each characterized by distinct molecular events that contribute to memory consolidation. What might ...
CircRNA-Based Therapeutics: a New Frontier in Neuroinflammation Treatment [0.03%]
基于环状circRNA的治疗:神经炎症治疗的新前沿
Thikra Majid Muhammed,Saade Abdalkareem Jasim,Subasini Uthirapathy et al.
Thikra Majid Muhammed et al.
Neuroinflammation is a complicated and multifactorial reaction in the central nervous system (CNS) that contributes to the pathophysiology of many neurological illnesses, such as neurodegenerative diseases and traumatic brain injury. Circul...
Araloside A Induces Raf/MEK/ERK-Dependent Autophagy to Mitigate Alzheimer's and Parkinson's Pathology in Cellular and C. elegans Models [0.03%]
Araloside A通过诱导Raf/MEK/ERK依赖的自噬减轻细胞和C. elegans模型中的阿尔茨海默症和帕金森病病理学
Xue Chen,Xing-Yue Zhou,Cai Lan et al.
Xue Chen et al.
Alzheimer's disease (AD) and Parkinson's disease (PD) are characterized by pathological protein aggregation and oxidative stress, leading to progressive neurodegeneration. Enhancing autophagy, the primary intracellular pathway for clearing ...
Protocadherin γC4 Promotes Neuronal Survival in the Mouse Retina Through Its Variable Cytoplasmic Domain [0.03%]
通过可变胞质结构域促进小鼠视网膜神经元存活的原钙粘蛋白γC4
Cathy M McLeod,Hannah G Lanthier,Garrett R Nitschke et al.
Cathy M McLeod et al.
Developmental apoptosis is an important mechanism for the formation of functional neural circuits. Distinct neuronal subtypes undergo apoptosis to a greater or lesser extent during development, although how this is regulated at the cell typ...
VEGF and the VEGF73-101 Fragment Prevent MPP+ Induced Mitochondrial Dysfunction in a Cell Model of Parkinson's Disease [0.03%]
VEGF及VEGF73-101片段通过改善线粒体功能障碍抑制多巴胺能神经元凋亡
Stefania Zimbone,Giuseppe Battiato,Stefano Conti Nibali et al.
Stefania Zimbone et al.
Vascular endothelial growth factor (VEGF) is best known for its role in angiogenesis, but emerging evidence suggests neurotrophic and neuroprotective functions most likely connected to energy homeostasis pathways. Using high-resolution resp...
Pentoxifylline as Adjuvant Therapy in Patients with Generalized Epilepsy Treated with Phenytoin: A Randomized Controlled Study [0.03%]
潘生丁作为苯妥英治疗全身性癫痫的辅助疗法的一项随机对照研究
Maha A Younis,Sahar M El-Haggar,Wessam Mustafa et al.
Maha A Younis et al.
Epilepsy is a persistent neurological condition that impacts millions of individuals globally. Neuroinflammation is regarded as a key contributor to the process of epileptogenesis. Several preclinical studies investigated the protective rol...
Reactive Oxygen Species Regulation Across Retinitis Pigmentosa Animal Models: A 25-Year Systematized Review [0.03%]
视网膜色素变性动物模型中活性氧的调节:为期25年的系统化综述
Rafael de Freitas Azevedo-Repossi,Rafael Brito,Marcelo Cossenza et al.
Rafael de Freitas Azevedo-Repossi et al.
Retinitis pigmentosa (RP) is a progressive, inherited retinal disorder characterized by the degeneration of photoreceptor cells, leading to vision loss. Due to the heterogeneous nature of the mutations underlying RP, treatment options remai...
Renal Denervation Improves Myocardial Mitochondrial Dysfunction and Myocardial Fibrosis by Inhibiting the NE/KLF15/renalase Pathway [0.03%]
肾去神经支配通过抑制NE/KLF15/肾素途径改善心肌线粒体功能障碍和心肌纤维化
Ye Chen,Ru Fu,Miao Huang et al.
Ye Chen et al.
Renal denervation (RDN) reduces cardiac sympathetic nerve activity maintained by arterial hypertension. This study aimed to investigate whether RDN affects myocardial mitochondrial oxidative stress and myocardial fibrosis through norepineph...
Correction: Sustaining Brain Youth by Neural Stem Cells: Physiological and Therapeutic Perspectives [0.03%]
纠正:通过神经干细胞保持大脑年轻的生理和治疗观点
Matilde Santos,João A Ferreira Moreira,Sónia Sá Santos et al.
Matilde Santos et al.
Published Erratum
Molecular neurobiology. 2025 Jul 30. DOI:10.1007/s12035-025-05260-2 2025