Tau Protein Disrupts Mitochondrial Homeostasis in a Yeast Model: Implications for Alzheimer's Disease [0.03%]
tau蛋白通过酵母模型干扰线粒体稳态及其在阿尔茨海默病中的意义
Yaisa Castillo-Casaña,Laura Kawasaki,Clorinda Arias et al.
Yaisa Castillo-Casaña et al.
The microtubule-associated protein tau plays a central role in neurodegenerative diseases, called tauopathies, but the mechanism involved remains incompletely understood. Here, we used Saccharomyces cerevisiae as a model system to investiga...
Interruption of the Gut Integrity Contributes to Early Accumulation of Amyloid-β in the Enteric Nervous System in Rats Supplemented with a High-Fat Diet [0.03%]
肠道完整性中断导致高脂饮食喂养大鼠肠神经系统早老素-β聚集增加
Zeinab Gawish,Maha Gamal,Dalia Azmy Elberry et al.
Zeinab Gawish et al.
Consumption of a high-fat diet (HFD) contributes to numerous chronic illnesses, including neurological disorders and gastrointestinal dysfunction. The study design included four groups, each consisting of six rats: the control group was fed...
Correction: Multi-Target Inhibitor of ZJQ- 3 F Against AChE/BACE1/GSK3β Targets Improves the Cognitive Impairment of APP/PS1/Tau Triple-Transgenic Mouse Models of Alzheimer's Disease [0.03%]
校正：ZJQ-3 F 多靶点胆碱酯酶/β-分泌酶1/糖原合成酶激酶3β抑制剂改善APP/PS1/Tau三转基因阿尔茨海默病小鼠模型的认知障碍
Nan Wang,Xin-Zhu Li,Xiao-Wen Jiang et al.
Nan Wang et al.
Published Erratum
Molecular neurobiology. 2025 Aug 7. DOI:10.1007/s12035-025-05265-x 2025
Downregulation of Glycogen Synthase Kinase-3 Beta by Urtica dioica L. Contributes to Neuroprotection Against Aluminum Chloride-Mediated Neurotoxicity in Zebrafish Larvae [0.03%]
牻牛儿苗通过下调甘油合成酶激酶-3β介导斑马鱼胚胎铝毒性神经保护作用研究
Rajneesh Kumar,Poonam Dhiman,Shiv Kumar Saini et al.
Rajneesh Kumar et al.
Urtica dioica L. (U. dioica; Family Urticaceae) has been utilized since ancient times, both as a nutritional source and for its therapeutic properties in addressing multiple disease conditions. The present study aimed to assess the neuropro...
Retraction Note to: MiR-126 Regulates the ERK Pathway via Targeting KRAS to Inhibit the Glioma Cell Proliferation and Invasion [0.03%]
撤回 notice:MiR-126通过靶向KRAS调节ERK途径以抑制胶质瘤细胞增殖和侵袭
Yang Li,Yunqian Li,Pengfei Ge et al.
Yang Li et al.
Komagataella pastoris KM71H Attenuates Cognitive Deficits and Depressive-Like Behavior by the TLR4/NF-κB Signaling Pathway in an Aβ1-40-Induced AD-Like Mouse Model [0.03%]
Komagataella pastoris KM71H通过TLR4 / NF-κB信号途径减轻Aβ1-40诱导的AD样小鼠模型的认知缺陷和类似抑郁的行为
Paloma T Birmann,Giuliana Petiz Zugno,Airton Sinott et al.
Paloma T Birmann et al.
Komagataella pastoris is a promising probiotic for modulating the microbiota-gut-brain axis, and growing evidence has demonstrated the relevance of this axis in the pathophysiology of neurological and psychiatric disorders, such as Alzheime...
Investigating Hippocampal Lateralization: Effects of Nickel on Neurobiological, AchE Activity, and Neurobehavioral Changes in the Wistar Rats [0.03%]
镍对wistar大鼠神经生物学、乙酰胆碱酯酶活性及神经行为学影响的脑区差异研究
Mohamed Yassine El Brouzi,Mouloud Lamtai,Rim Bousalham et al.
Mohamed Yassine El Brouzi et al.
Nickel (Ni) is a heavy metal that is widely distributed in the environment and has harmful effects on human health, especially the central nervous system. Ni's accumulation capacity makes the hippocampus, a crucial brain region for memory a...
An Exploratory Analysis of Differential Tear Fluid miRNAs in Patients with Parkinson's Disease and Atypical Parkinsonian Syndromes [0.03%]
帕金森病和非典型性帕金森综合征患者泪液miRNA差异表达的探索性分析
Antonia F Demleitner,Lucas Caldi Gomes,Lara Wenz et al.
Antonia F Demleitner et al.
Parkinson's disease (PD), multiple system atrophy (MSA), and progressive supranuclear palsy (PSP) are neurodegenerative disorders diagnosed by clinical criteria with limited diagnostic specificity in early stages. Diagnostic biomarkers faci...
Using Blood-Based Biomarkers to Facilitate the Diagnosis of Alzheimer's Disease: Insights from a Novel Pyroptosis-Associated Molecular Signature Model [0.03%]
利用血液生物标志物辅助阿尔茨海默病诊断：新型焦亡相关分子特征模型的启示
Weimin Ren,Xiaobo Yang
Weimin Ren
Alzheimer's disease (AD) stands as the primary reason for aging-related dementia and is swiftly becoming recognized as one of the century's most expensive, fatal, and burdensome illnesses, which calls for more convenient diagnostic methods....
Knock-out of Tpm4.2/Actin Filaments Alters Neuronal Signaling, Neurite Outgrowth, and Behavioral Phenotypes in Mice [0.03%]
TPM4.2/肌动蛋白丝敲除小鼠中神经信号、轴突生长和行为表型的改变
Sian Genoud,Chanchanok Chaichim,Rossana Rosa Porto et al.
Sian Genoud et al.
Tropomyosins (Tpm) are master regulators of actin dynamics through forming co-polymers with filamentous actin. Despite the well-understood function of muscle Tpms in the contractile apparatus of muscle cells, much less is known about the di...