Correction: Edaravone Maintains AQP4 Polarity Via OS/MMP9/β-DG Pathway in an Experimental Intracerebral Hemorrhage Mouse Model [0.03%]
关于:Edaravone通过OS/MMP9/β-DG通路维持AQP4极性在实验性脑出血小鼠模型中的纠正研究
Zhenhua Wang,Yuan Li,Zhixu Wang et al.
Zhenhua Wang et al.
Published Erratum
Molecular neurobiology. 2024 Jun 4. DOI:10.1007/s12035-024-04275-5 2024
PGK1 Is Involved in the HIF-1 Signaling Pathway as a Hub Gene for Ferroptosis After Traumatic Brain Injury [0.03%]
PGK1是创伤性脑损伤后铁死亡的核心基因并参与HIF-1信号通路
Zhao Wang,Jinjie Tian,Lei Wang et al.
Zhao Wang et al.
The pathogenesis of ferroptosis in traumatic brain injury (TBI) is unclear; therefore, we aimed to identify key molecules associated with ferroptosis in TBI using bioinformatics analysis to determine its underlying mechanisms. GSE128543 dat...
Knockdown of DJ-1 Exacerbates Neuron Apoptosis Induced by TgCtwh3 through the NF-κB Pathway [0.03%]
下调DJ-1通过NF-κB通路加重TgCtwh3诱导的神经元凋亡
Di Yang,Minmin Wu,Nian Zou et al.
Di Yang et al.
Mutations or loss of function of DJ-1 and Toxoplasma gondii (T. gondii) infection has been linked to neurodegenerative diseases, which are often caused by oxidative stress. However, the relationship between DJ-1 and T. gondii infection is n...
Revolutionizing Stroke Care: Nanotechnology-Based Brain Delivery as a Novel Paradigm for Treatment and Diagnosis [0.03%]
革命性卒中护理:基于纳米技术的脑递送作为治疗和诊断的新范例
Paul Gajanan Balaji,Londhe Sachin Bhimrao,Awesh K Yadav
Paul Gajanan Balaji
Stroke, a severe medical condition arising from abnormalities in the coagulation-fibrinolysis cycle and metabolic processes, results in brain cell impairment and injury due to blood flow obstruction within the brain. Prompt and efficient th...
BDNF-VGF Pathway Aggravates Incision Induced Acute Postoperative Pain via Upregulating the Neuroinflammation in Dorsal Root Ganglia [0.03%]
脑源性神经营养因子-VGF信号通路通过上调背根神经节的神经炎症加重术后急性疼痛
Wenjing Zhao,Lulin Ma,Daling Deng et al.
Wenjing Zhao et al.
Approximately one-third of postoperative patients are troubled by postoperative pain. Effective treatments are still lacking. The aim of this study is to investigate the role of brain-derived neurotrophic factor (BDNF)-VGF (non-acronymic) i...
CELF2 Deficiency Demonstrates Autism-Like Behaviors and Interferes with Late Development of Cortical Neurons in Mice [0.03%]
CELF2缺陷会导致小鼠自闭症样行为并干扰皮层神经元的晚期发育
Xinyu Duan,Xiaoxia Peng,Xiangbin Jia et al.
Xinyu Duan et al.
CELF2 variants have been linked to neurodevelopmental disorders (NDD), including autism spectrum disorder (ASD). However, the molecular mechanisms remain unclear. We generated Celf2 Nestin-Cre knockout mice.Our findings revealed that Celf2 ...
Shishi Jiang,Renshi Xu
Shishi Jiang
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease mainly characterized by the accumulation of ubiquitinated proteins in the affected motor neurons. At present, the accurate pathogenesis of ALS remains unclear and ther...
Noradrenergic Regulation of the Medial Prefrontal Cortex Mediates Stress Coping in Postpartum Female Mice [0.03%]
产后小鼠应对压力的 noradrenergic 调节机制及介导行为反应的神经环路研究:基于纹状皮层的研究
Ikuko Horie,Yoshikage Muroi,Toshiaki Ishii
Ikuko Horie
The prevalence of depression in women increases during the postpartum period. We previously reported that subchronic exposure to social stress decreased passive coping in postpartum female mice. This study aimed to investigate whether norad...
Ido2 Deficiency Exacerbates Motor Impairment and Reduces Aryl Hydrocarbon Receptor Activity through Decreased Kynurenine in a Chronic Demyelinating Mouse Model [0.03%]
Ido2缺陷通过降低犬尿氨酸加重慢性脱髓鞘小鼠模型的运动障碍和减少芳香烃受体活性
Kazuo Kunisawa,Mitsuki Hara,Koyo Yoshidomi et al.
Kazuo Kunisawa et al.
Demyelinating diseases including multiple sclerosis (MS) are chronic inflammatory diseases of the central nervous system. Indoleamine 2,3-dioxygenase 2 (Ido2) is a recently identified as catalytic enzyme involved in the rate-limiting step o...
Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson's Disease [0.03%]
miRNA及其靶基因在帕金森病发病机制和治疗中的作用及机理研究
Tania Arora,Gaurav Sharma,Vikash Prashar et al.
Tania Arora et al.
MicroRNA (miRNA) are usually 18-25 nucleotides long non-coding RNA targeting post-transcriptional regulation of genes involved in various biological processes. The function of miRNA is essential for maintaining a homeostatic cellular condit...