Hydro-Alcoholic Extract of Cynodon dactylon Ameliorates Malathion-Induced Neurocognitive Behavior and Neurotoxicity [0.03%]
钝叶草醇提物对马拉硫磷致神经行为和神经毒性的改善作用
Divyansh Sharma,Sakshi Mishra,Gaurav Jha et al.
Divyansh Sharma et al.
Organophosphate insecticides like malathion, though less toxic than other compounds in the same class, remain a significant public health concern due to their widespread use and potential neurotoxic effects. Prolonged exposure to malathion ...
Improvement of Parkinson's Disease Symptoms by Butylphthalide Through Modulation of Microglial Activation [0.03%]
乙苯脂通过调节小胶质细胞活化改善帕金森症状研究进展
Xue Wang,Huimin Shi,Zibin Wei et al.
Xue Wang et al.
Microglia-mediated neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). Studies have shown that butylphthalide (3-n-butylphthalide or NBP) can play an anti-inflammatory role in other diseases by regulat...
Electro-Acupuncture Therapy Alleviates Post-Stroke Insomnia by Regulating Sirt1 and the Nrf2-ARE Pathway [0.03%]
电针治疗通过调节Sirt1和Nrf2-ARE途径缓解卒中后失眠
Yiming Wang,Yifei Chen,Jianbo Yang et al.
Yiming Wang et al.
Post-stroke insomnia (PSI) is a common complication following stroke, which seriously affects patients' life quality. Electro-acupuncture (EA) is an innovative form of traditional Chinese acupuncture that combines electricity with needles t...
Unlocking Alzheimer's Disease: The Role of BDNF Signaling in Neuropathology and Treatment [0.03%]
解密阿尔茨海默病：脑源性神经营养因子信号通路在神经病理及治疗中的作用
Saad Misfer Alqahtani,Hayder M Al-Kuraishy,Ali I Al Gareeb et al.
Saad Misfer Alqahtani et al.
Alzheimer's disease (AD) remains one of the most debilitating neurodegenerative disorders, with its pathological hallmark being progressive cognitive decline and memory loss. Recent research has illuminated the crucial role of the brain-der...
The Conceivable Role of Metabolic Syndrome in the Pathogenesis of Alzheimer's Disease: Cellular and Subcellular Alterations in Underpinning a Tale of Two [0.03%]
代谢综合征在阿尔茨海默病发病机制中的潜在作用：细胞和亚细胞改变讲述的两个故事
Ekremah A Alzarea,Hayder M Al-Kuraishy,Ali I Al-Gareeb et al.
Ekremah A Alzarea et al.
Alzheimer's disease (AD)is an age-related neurodegenerative disease characterized by memory decline and cognitive impairment .AD is common in people aged > 65 years, though most of AD cases are sporadic, which accounts for 95%, and 1-5% of ...
Far-Infrared Radiation Ameliorates the Cognitive Dysfunction in an Alzheimer's Disease Transgenic Mouse via Modulating Jak-2/Stat3 and Nrf-2/HO-1 Pathways [0.03%]
远红外辐射通过调节Jak-2/Stat3和Nrf-2/HO-1信号通路改善阿尔茨海默病转基因小鼠认知障碍作用的研究
Wen Yang,Qiuxia Yu,Nick Wang et al.
Wen Yang et al.
Alzheimer's disease (AD) is the primary cause of dementia in the elderly. However, effective therapies that modify the disease process in AD remain elusive. Far-infrared radiation (FIR) is commonly utilized as a complementary treatment a ra...
Composition and Neurogenetic Effects of Embryonic Cerebrospinal Fluid: A Systematic Review [0.03%]
胚胎脑脊液的组成及神经遗传效应：系统性综述
Ana Călina Beldean,Radu Cristian Moldovan,Olga Sorițău et al.
Ana Călina Beldean et al.
Embryonic cerebrospinal fluid (E-CSF) has an important role in neurological development. Due to limited availability, the composition and properties of E-CSF are not known to the present. Our review aims to offer a comprehensive perspective...
Spatiotemporal Expression of IRS-1 During Brain Development and its Role in Neural Stem Cell Differentiation [0.03%]
IRS-1在脑发育过程中的时空表达及其在神经干细胞分化中的作用
Junjiao Zhang,Xiao Li,Fan Zhang et al.
Junjiao Zhang et al.
Insulin receptor substrate 1 (IRS-1) is a key mediator of insulin signaling linked to focal cortical dysplasia. While previous studies have primarily focused on IRS-1 in peripheral tissues, its function in the central nervous system has rem...
Transcranial Magnetic Stimulation Alleviates Spatial Learning and Memory Impairment by Inhibiting the Expression of SARM1 in Rats with Cerebral Ischemia-Reperfusion Injury [0.03%]
经颅磁刺激通过抑制缺血再灌注损伤大鼠SARM1表达改善空间学习记忆障碍
Linlin Jiang,Yule Wang,Yingxi He et al.
Linlin Jiang et al.
The cognitive impairment resulting from stroke is purported to be associated with impaired neuronal structure and function. Transcranial Magnetic Stimulation (TMS) modulates neuronal or cortical excitability and inhibits cellular apoptosis,...
Adhesion-Related Pathways and Functional Polarization of Astrocytes in Traumatic Brain Injury: Insights from Single-cell RNA Sequencing [0.03%]
单细胞RNA测序揭示的创伤性脑损伤中的粘附相关通路和星形胶质细胞的功能极化
Xiaoyan Liu,Ji Xia,Wenjing Shao et al.
Xiaoyan Liu et al.
Traumatic brain injury (TBI) induces profound functional heterogeneity in astrocytes, yet the regulatory mechanisms underlying this diversity remain poorly understood. In this study, we analyzed single-cell RNA sequencing data from the cort...