Therapeutic potential of extracellular vesicles in systemic lupus erythematosus: a systematic review [0.03%]
外泌体在系统性红斑狼疮治疗中的潜力：一项系统综述
Renata Vaz Voltareli,Nayara Rozalem Moretti,Giovanni Garrido Puci et al.
Renata Vaz Voltareli et al.
Current therapies for Systemic lupus erythematosus (SLE), such as immunosuppressants and glucocorticoids, are associated with significant side effects, necessitating alternative treatment approaches. Extracellular vesicles (EVs) have emerge...
GFAP as a marker of astrocytic damage correlated with medication overuse in migraine [0.03%]
GFAP可作为偏头痛药物过量使用的星形胶质细胞损伤标志物
Sara Carta,Vanessa Chiodega,Riccardo Tiberi et al.
Sara Carta et al.
Different mechanisms are involved in migraine pathogenesis, including neurogenic inflammation, neurodegenerative processes, and a potential role of microglia. The aim of this study was to assess axonal and glial damage measuring serum level...
The role of CD40L-expressing CXCR5+CD8+ follicular cytotoxic T cells in chronic lymphocytic leukemia [0.03%]
表达CD40L的CXCR5+CD8+滤泡性细胞毒T细胞在慢性淋巴细胞性白血病中的作用
Fatih Akboga,Fehmi Hindilerden,Ipek Yonal Hindilerden et al.
Fatih Akboga et al.
A newly identified cell subset within CD8+ T cells expressing CXCR5 of follicular cytotoxic T cells (TFC) lyse the infected or tumor cells. Recent studies have suggested that some TFC cell subsets may be involved in the regulation of antibo...
Immunoglobulin G4-related sclerosing mastitis: MRI findings and the literature review [0.03%]
免疫球蛋白G4相关硬化性乳腺炎的磁共振成像表现及文献复习
Lishan Wang,Fan Yang,Xiaoyan Hu et al.
Lishan Wang et al.
Immunoglobulin G4-related disease (IgG4-RD) is a rare immune-mediated fibro-inflammatory condition that can affect nearly any organ, with breast involvement (IgG4-related sclerosing mastitis, IgG4-RM) being exceptionally uncommon. This dise...
Effects of belimumab on peripheral blood Breg cells and cytokines in childhood systemic lupus erythematosus [0.03%]
贝利尤单抗对儿童系统性红斑狼疮外周血Breg细胞及细胞因子的影响
Qianqian Peng,Ruifeng Zhang,Shan Qiu et al.
Qianqian Peng et al.
To evaluate the therapeutic effectiveness of belimumab (BLM) in childhood systemic lupus erythematosus (cSLE) by analyzing peripheral blood Breg cell subsets and related cytokines at multiple time points post-treatment, compared with conven...
SOCS1 improves abnormal IgA galactosylation in IgA nephropathy by regulating the TLR9/MyD88 pathway [0.03%]
SOCS1通过调节TLR9/MyD88通路改善IgA肾病异常的IgA半乳糖化
Yanru Huang,Qinghai Wang,Chunqin Lin et al.
Yanru Huang et al.
Abnormal galactosylation of IgA is a core factor in the development of IgA nephropathy (IgAN). Suppressor of cytokine signaling 1 (SOCS1) expression negatively correlates with IgA1 secretion in IgAN patients and that TLR9/MyD88 promotes abe...
Exploring the role of the Th9/IL-9 axis in atopic dermatitis: analysis of Th9 cells, PU.1 expression and serum IL-9 levels [0.03%]
探究Th9/IL-9轴在线性湿疹中的作用：Th9细胞、PU.1表达及血清IL-9水平分析
Tabasum Shafi,Roohi Rasool,Rubeena Bhat et al.
Tabasum Shafi et al.
Atopic dermatitis (AD) is a chronic inflammatory skin disease resulting from complex interactions between genetic, environmental, and immunological factors, particularly the dysregulation of T helper (Th) cell subsets. While Th2 responses h...
Severe interstitial lung disease as the first manifestation of a STING1 variant in a familial case [0.03%]
家族性STING1新变异基因导致的严重间质性肺病病例报告
Zhijuan Kang,Ruqian Fu,Zhihui Li et al.
Zhijuan Kang et al.
STING-associated vasculopathy with onset in infancy (SAVI) is a very rare autosomal-dominant Mendelian autoinflammatory disease caused by heterozygous gain-of-function mutations in STING1. Reported carriers of a STING1 gain-of-function muta...
SPP1 + macrophages facilitate pancreatic cancer progression via ITGB6-mediated interactions: evidence from integrated multi-omics analysis and experimental validation [0.03%]
整合多组学分析和实验验证表明SPP1+巨噬细胞通过ITGB6介导的相互作用促进胰腺癌进展
Jiachen Ge,Jianping Cai,Gaolei Zhang et al.
Jiachen Ge et al.
Basement membranes (BMs) and tumor-associated macrophages (TAMs) are crucial stromal components in pancreatic cancer (PC), critically influencing disease progression. Bulk and single-cell RNA-seq (scRNA-seq) data were acquired from publicly...
Sumin Yan,Bingqiu Han,Chao Song et al.
Sumin Yan et al.
Discogenic low back pain (DLBP) is one of the main causes of chronic low back pain, and its core pathological mechanism is due to various molecular changes caused by intervertebral disc degeneration. The normal intervertebral disc is compos...