miR-452-5p promotes systemic lupus erythematosus-induced inflammatory responses by downregulating RBL2 and impairing Treg development [0.03%]
miR-452-5p通过下调RBL2并影响Treg发育促进系统性红斑狼疮诱导的炎症反应
Xinchao Zhai,Fengjiao Gui,Meini Cen et al.
Xinchao Zhai et al.
Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Studies have reported that miR-452-5p is highly expressed in SLE, while RBL2 is downregulated. This study aims to investigate the diagnostic value of miR-452-5p in distingu...
Sadichha Sanjay Mantri,Gaurav Mahesh Doshi
Sadichha Sanjay Mantri
Expression of key genes in IVIG-unresponsive Kawasaki disease and their immune correlation based on bioinformatics analysis [0.03%]
生物信息学分析免疫球蛋白无反应的川崎病关键基因表达及免疫相关性研究
Zheng-Han Zhao,Xi-Yu Yang,He Zhang et al.
Zheng-Han Zhao et al.
This study employed bioinformatics to analyze the gene expression profile of Kawasaki disease (KD) patients and identify key genes associated with intravenous immunoglobulin (IVIG) non-response. The aim was to elucidate the pathogenesis of ...
Correction: Association of HLA-B alleles with Familial mediterranean fever (FMF): A comparative study [0.03%]
校正:与地中海发热(FMF)相关的HLA-B等位基因:一项比较研究
Utku Aksu,Pınar Aksu Kılıçle,Sevim Gönen
Utku Aksu
Published Erratum
Immunologic research. 2026 Jan 19;74(1):9. DOI:10.1007/s12026-026-09748-4 2026
Single-cell atlas of axial skeletal immune-matrix interaction in spondylitis [0.03%]
轴向脊椎炎免疫-基质相互作用的单细胞图谱
Sanmu Wang,Mingjie Xu,Pengfei Zhang et al.
Sanmu Wang et al.
Axial skeletal involvement is central to ankylosing spondylitis, yet the in situ interplay between immune effectors (especially cytotoxic T lymphocytes) and the bone matrix microenvironment remains poorly resolved. Prior single-cell studies...
mRNA-Encoded antibodies as a next-generation therapeutic paradigm: a rapid and adaptive platform for the prevention and treatment of emerging and re-emerging infectious diseases - A critical review [0.03%]
以mRNA编码抗体作为下一代治疗范例:一种用于预防和治疗新兴及再现性传染病的快速适应平台——批判性综述
Dilpreet Singh
Dilpreet Singh
Messenger RNA (mRNA)-encoded antibodies represent a transformative therapeutic platform with the potential to rapidly combat emerging infectious diseases by enabling in situ expression of potent neutralizing antibodies directly in the patie...
Current and projected trends in rheumatoid arthritis among postmenopausal women in the U.S.: a population-based analysis of the Global Burden of Disease Study 2021, with projections to 2035 [0.03%]
基于全球疾病负担研究2021年的美国绝经后妇女类风湿性关节炎的现况及至2035年预测:人群为基础的分析
Wen Liu,Xiaoling Mo,Shengqian Xu
Wen Liu
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder with a high prevalence among postmenopausal women (PMW), and it is associated with substantial functional impairment and reduced quality of life. To inform targeted pre...
Comparative disease burden and trends of autoimmune diseases in China and G20 countries: an analysis of the global burden of disease study 2023 [0.03%]
中国与二十国集团国家自身免疫疾病负担及趋势比较:对全球疾病负担研究2023的分析
Rongxing Qin,Xinyu Lai,Qingchun Qin et al.
Rongxing Qin et al.
Association of HLA-B alleles with familial mediterranean fever (FMF): A comparative study [0.03%]
HLA-B等位基因与家族地中海热(FMF)的关系:一项比较研究
Utku Aksu,Pınar Aksu Kılıçle,Sevim Gönen
Utku Aksu
Objective: Familial Mediterranean Fever (FMF) is the most prevalent monogenic autoinflammatory disorder. In the present study, we investigated whether HLA-B polymorphisms contribute to familial Mediterranean fever (FMF) s...
Comparative Study
Immunologic research. 2026 Jan 9;74(1):4. DOI:10.1007/s12026-025-09729-z 2026
SALL4-targeted therapeutic peptide PEN-FFW suppresses PD-L1 and enhances CD8⁺ T cell cytotoxicity via regulating PI3K/AKT signaling in breast cancer [0.03%]
靶向SALL4的治疗性肽PEN-FFW通过调节PI3K/AKT信号通路抑制PD-L1并增强CD8⁺T细胞毒性以治疗乳腺癌
Renyuan Xu,Haomiao Lan,Li Zhang et al.
Renyuan Xu et al.
SALL4 is aberrantly reactivated in multiple malignancies, including breast cancer (BC), where it promotes tumor progression and therapy resistance. However, its therapeutic targeting remains underexplored. This study investigates the antitu...