TNFR-CD3-engineered regulatory T cells attenuate neuroinflammation and neuropathic pain [0.03%]
经工程改造的调节性T细胞（TNFR-CD3工程化的调节性T细胞）可减轻神经炎症和神经病理性疼痛
Pei Li,Ying Yan,Shan Wu et al.
Pei Li et al.
Reduction of regulatory B cells is associated with high-risk clinical stratification in antiphospholipid syndrome patients [0.03%]
抗磷脂综合征患者的调节性B细胞减少与高危临床分层相关
Rui Ma,You-Yang Wang,Jing-Hong Feng et al.
Rui Ma et al.
CRISPR-Cas9-based gene editing as a proof-of-concept approach in an inborn error of immunity caused by a DCLRE1C variant [0.03%]
基于CRISPR-Cas9的基因组编辑技术矫正DCLRE1C突变引起的原发免疫缺陷病
Tugce Duran,Mehmet Ali Karaselek,Burak Dagdelen et al.
Tugce Duran et al.
Hypomorphic DCLRE1C variants impair T and B cell development, leading to combined immunodeficiency (CID) or leaky severe combined immunodeficiency (SCID). Current treatment options, such as allogeneic hematopoietic stem cell transplantation...
Antonino Messina
Antonino Messina
Efficacy of chimeric antigen receptor natural killer cells in treatment of ovarian cancer. A meta-analysis of pre-clinical studies [0.03%]
嵌合抗原受体自然杀伤细胞治疗卵巢癌的疗效：一项前期研究的meta分析
Nabeel Ahmed,Jawaria Jabeen,Malja Rehman et al.
Nabeel Ahmed et al.
Chimeric antigen receptor (CAR) therapies have expanded beyond T-cells with addition of natural killer (NK) cells. In ovarian cancer, long-term survival remains poor with the rising need for new therapies. Therefore, this meta-analysis eval...
Meta-Analysis
Immunologic research. 2026 Feb 20;74(1):17. DOI:10.1007/s12026-026-09750-w 2026
The role of metal metabolism in inflammatory bowel disease: Pathogenesis, clinical application, and therapeutic targets [0.03%]
金属代谢在炎症性肠病中的作用：病理机制、临床应用和治疗靶点
Huangeng Zhao,Yuchao Sun,Lele Li et al.
Huangeng Zhao et al.
Prevalence and clinical associations of anti-rods and rings antibodies in ANA-tested patients [0.03%]
ANA阳性患者中抗杆状环形核抗体的流行率及临床特征分析
Baris Can,Arzu Aksit Ilki
Baris Can
Anti-rods and rings (anti-RR) antibodies represent a rare cytoplasmic antinuclear antibody (ANA) pattern typically associated with hepatitis C virus (HCV) infection and interferon-based therapy. However, emerging evidence suggests a broader...
Elevated levels of advanced glycation end-products AGE10 in patients with reactive arthritis caused by Chlamydia trachomatis and Epstein-Barr virus infection [0.03%]
沙眼衣原体和Epstein-Barr病毒感染所致反应性关节炎患者AGE水平升高
Iryna Kril,Svitlana Zubchenko,Anna Havrylyuk et al.
Iryna Kril et al.
Advanced glycation end products (AGEs), and particularly the unique AGE10 epitope, may be a potential biomarker of immunopathology in rheumatic diseases. They may be associated with inflammation, joint damage and ossification processes. AGE...
Innate lymphoid cells: unsung heroes or villains in multiple sclerosis pathogenesis? [0.03%]
固有淋巴样细胞：多发性硬化发病机制中的无名英雄还是幕后黑手？
Mansur Aliyu,Ali Akbar Saboor-Yaraghi,Mohamad Ali Sahraian et al.
Mansur Aliyu et al.
The emerging role of Innate Lymphoid Cells (ILCs) in the pathogenesis and regulation of Multiple Sclerosis (MS), a complex neuroinflammatory autoimmune disease, has been increasingly recognized. Once identified only for activities conducted...
Rare KDM4C variants and reduced expression underlie epigenetic dysregulation in rheumatoid arthritis [0.03%]
KDM4C罕见变异和表达降低导致类风湿关节炎的表观遗传调控异常
Deniz Aslar Oner,Hasan Toktas,Umit Dundar et al.
Deniz Aslar Oner et al.
This study aims to investigate structural and expression-level alterations in the histone demethylase KDM4C gene in patients with rheumatoid arthritis (RA) and elucidate its role in the disease's epigenetic basis. KDM4C sequencing was perfo...