A Contemporary Appraisal on Impending Industrial and Agricultural Applications of Thermophilic-Recombinant Chitinolytic Enzymes from Microbial Sources [0.03%]
来自微生物来源的耐热型-重组壳多糖酶在工业和农业应用中的前景及现状评估
Fatima Akram,Zuriat Jabbar,Amna Aqeel et al.
Fatima Akram et al.
The ability of chitinases to degrade the second most abundant polymer, chitin, into potentially useful chitooligomers and chitin derivatives has not only rendered them fit for chitinous waste management but has also made them important from...
The Protective Effect of UBE2G2 Knockdown Against Atherosclerosis in Apolipoprotein E-Deficient Mice and Its Association with miR-204-5p [0.03%]
UBE2G2基因敲低对载脂蛋白E缺乏型小鼠动脉粥样硬化保护作用及与miR-204-5p的关系研究
Yangyang Liu,Zhouyu Luo,Zhendong Wu et al.
Yangyang Liu et al.
Atherosclerosis (AS) is a chronic and progressive inflammatory disease. Ubiquitin-conjugating enzyme E2G 2 (UBE2G2) has been reported to be differentially expressed in subjects with abnormal coronary endothelial function. We intended to fur...
Circular RNA has Circ 001372-Reduced Inflammation in Ovalbumin-Induced Asthma Through Sirt1/NFAT5 Signaling Pathway by miRNA-128-3p [0.03%]
环状RNA通过miR-128-3p/Sirt1/NFAT5信号通路下调Circ 001372缓解卵清蛋白诱导的小鼠哮喘炎症
Hongrui Lin,Naijun Wan
Hongrui Lin
In this study, we sought to investigate the prospective role of circ 001372 in modifying inflammation in ovalbumin-induced asthma. In the vivo model of asthma, the serum of circ 001372 was reduced. Down-regulation of circ 001372 increased i...
The Circular RNA circSKA3 Facilitates the Malignant Biological Behaviors of Medulloblastoma via miR-520 h/CDK6 Pathway [0.03%]
circRNA circSKA3通过miR-520 h/CDK6通路促进髓母细胞瘤的恶性生物学行为
Xu-Chang Liu,Fa-Chen Wang,Ji-Hong Wang et al.
Xu-Chang Liu et al.
Circular RNAs (circRNAs) are reported to participate in the development of diverse human malignancies. This work investigated the mechanism of circSKA3 in modulating medulloblastoma progression. A total of 15 cases of medulloblastoma were c...
Apoplastic Production of Recombinant AntiVEGF Protein Using Plant-Virus Transient Expression Vector [0.03%]
利用植物病毒瞬时表达载体进行胞外抗VEGF蛋白的表达
Mojgan Soleimanizadeh,Mokhtar Jalali Javaran,Abdolreza Bagheri et al.
Mojgan Soleimanizadeh et al.
Targeting of vascular endothelial growth factor (VEGF) using AntiVEGF can be a promising approach for angiogenesis inhibition and cancer therapy. In this study, we direct AntiVEGF recombinant protein accumulation to cucurbit plant apoplast ...
Methods for CRISPR-Cas as Ribonucleoprotein Complex Delivery In Vivo [0.03%]
体内递送CRISPR-Cas核糖核蛋白复合物的方法
Alesya G Bykonya,Alexander V Lavrov,Svetlana A Smirnikhina
Alesya G Bykonya
The efficient delivery of CRISPR-Cas components is still a key and unsolved problem. CRISPR-Cas delivery in the form of a Cas protein+sgRNA (ribonucleoprotein complex, RNP complex), has proven to be extremely effective, since it allows to i...
MiR-125b-5p/TPD52 Axis Affects Proliferation, Migration and Invasion of Breast Cancer Cells [0.03%]
miR-125b-5p/TPD52轴影响乳腺癌细胞的增殖、迁移和侵袭
Yuezhen Wang,Jun Fang,Feiying Gu
Yuezhen Wang
Aberrant gene expression caused by miRNAs disorders plays a relevant role in multiple steps of tumorigenesis. In this attempt, we studied the functional role of miR-125b-5p and TPD52 in breast cancer. TPD52 mRNA and miR-125b-5p levels were ...
Correction to: LncRNA NCK1-AS1 Promotes Malignant Cellular Phenotypes of Laryngeal Squamous Cell Carcinoma via miR-137/NCK1 Axis [0.03%]
关于长链非编码RNA NCK1-AS1通过miR-137/NCK1轴促进喉鳞状细胞癌恶性表型的订正通知
Lanlan Wan,Dongsheng Gu,Xin Jin
Lanlan Wan
Published Erratum
Molecular biotechnology. 2022 Aug;64(8):945-946. DOI:10.1007/s12033-022-00478-0 2022
Response Surface Methodology Based Optimization, Partial Purification and Characterization of Alkaline Phosphatase Isolated from Pseudomonas asiatica Strain ZKB1 and its Application in Plant Growth Promotion [0.03%]
基于响应面法的假单胞菌ZKB1碱性磷酸酶的优化、部分纯化及特性研究及其促植物生长的应用研究
Zabin K Bagewadi,Deepak A Yaraguppi,Sikandar I Mulla et al.
Zabin K Bagewadi et al.
The present study was defined to evaluate the effect of a combinational approach of applying phosphate-solubilizing bacteria and alkaline phosphatase for plant growth promotion as a novel strategy. An extracellular phosphatase producing nov...
LncRNA MAFG-AS1 Promotes Lung Adenocarcinoma Cell Migration and Invasion by Targeting miR-3196 and Regulating SOX12 Expression [0.03%]
长链非编码RNA MAFG-AS1通过靶向miR-3196并调节SOX12表达来促进肺腺癌细胞迁移和侵袭
Qian Wu,Jianyang Jiang
Qian Wu
Lung adenocarcinoma (LUAD) patients exhibit poor prognosis, primarily due to metastasis. Emerging studies have demonstrated that long noncoding RNAs (lncRNAs) play critical roles in cancer progression and metastasis besides their physiologi...