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Methods for CRISPR-Cas as Ribonucleoprotein Complex Delivery In Vivo

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The efficient delivery of CRISPR-Cas components is still a key and unsolved problem. CRISPR-Cas delivery in the form of a Cas protein+sgRNA (ribonucleoprotein complex, RNP complex), has proven to be extremely effective, since it allows to increase on-target ac... ...