Irit Carmi-Levy,Bernhard Homey,Vassili Soumelis
Irit Carmi-Levy
Atopic dermatitis (AD) is a chronic inflammatory skin disease known for its complex pathophysiology involving several immune pathways. In the lesion, signals from barrier disruption, allergens, and microbial colonization are integrated and ...
Andrew L Chan,Rokhsara Rafii,Samuel Louie et al.
Andrew L Chan et al.
Idiopathic pulmonary fibrosis (IPF) is a disease of the elderly with a mean age at presentation of 66 years. It is the most common type of idiopathic lung fibrosis, and the most lethal, with a median survival of 3 to 5 years after diagnosis...
The clinical significance of coagulation and the inflammatory response in autoimmunity [0.03%]
自身免疫中凝血与炎症反应的临床意义
Benjamín Rubio-Jurado,Paulina Iñiguez-Franco,Pedro A Reyes et al.
Benjamín Rubio-Jurado et al.
Maintenance of normal blood flow requires equilibrium between procoagulant and anticoagulant factors; occasionally, procoagulant activity predominates, leading to clot formation; frequently, tissue damage is the triggering factor. Hereditar...
Ilan Ben-Zvi,Shaye Kivity,Pnina Langevitz et al.
Ilan Ben-Zvi et al.
Quinine was first recognized as a potent antimalarial agent hundreds of years ago. Since then, the beneficial effects of quinine and its more advanced synthetic forms, chloroquine and hydroxychloroquine, have been increasingly recognized in...
Aaron Lerner,Yinon Shapira,Nancy Agmon-Levin et al.
Aaron Lerner et al.
Reduced bone mineral density is frequently found especially in adult celiac disease (CD) and dietary guidelines favor vitamin D supplementation in adults and children with CD. Vitamin D serum levels were investigated in CD populations in or...
Andrew L Chan,Samuel Louie,Kevin O Leslie et al.
Andrew L Chan et al.
Goodpasture's disease, or anti-glomerular basement membrane (anti-GBM) disease, is a systemic autoimmune disorder defined by anti-GBM antibody-mediated damage (mainly immunoglobulin G-1) resulting in progressive crescentic glomerulonephriti...
The clinical and diagnostic significance of anti-myosin autoantibodies in cardiac disease [0.03%]
抗肌球蛋白自身抗体在心脏疾病中的临床和诊断意义
Udi Nussinovitch,Yehuda Shoenfeld
Udi Nussinovitch
Autoimmunity is influenced by genetic, immune, hormonal, and environmental factors. Viral infections may trigger autoimmunity. It has been established that autoimmunity may be a contributing factor in the pathogenesis of heart disease. Anti...
Ulf Darsow,Florian Pfab,Michael Valet et al.
Ulf Darsow et al.
Atopic eczema is one of the most pruritic skin diseases. Mediators of atopic eczema itch in the skin are still mostly unknown, but recent studies showed that the histamine 4 receptor plays an important role in itch pathophysiology; tryptase...
The diagnostic and clinical significance of anti-muscarinic receptor autoantibodies [0.03%]
胆碱能受体自免抗体的诊断和临床意义分析
Udi Nussinovitch,Yehuda Shoenfeld
Udi Nussinovitch
The role of autoimmunity in cardiovascular diseases has become one of the focal points of research studies. Autoimmune response and autoreactive autoantibodies have been found in dilated cardiomyopathy, heart failure, rheumatic fever, myoca...
Diego Vergani,Giorgina Mieli-Vergani
Diego Vergani
Autoimmune hepatitis is an inflammatory liver disease affecting mainly females and characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by circulating autoantibodies and increa...