Huihui Hou,Yueqi Qiu,Ming Zhao
Huihui Hou
In the intricate regulation of gene expression, multiple regulatory elements play crucial roles. Among these, enhancers stand out as important elements that can boost the activity of promoters and make target genes more likely to be transcr...
Islet Tissue Macrophages in Immunity Homeostasis and Type 1 Diabetes [0.03%]
胰岛组织巨噬细胞在免疫稳态和1型糖尿病中的作用
Yan Wang,Zhaoran Wang,Wenya Diao et al.
Yan Wang et al.
Islet macrophages are considered to be irreplaceable in maintaining the immune microenvironment homeostasis. The M1/M2 imbalance can trigger the initiation of islet autoimmunity and persists throughout the entire process of type 1 diabetes....
Hongzheng Wu,Xiaomeng Li,Honglin Xu et al.
Hongzheng Wu et al.
Idiopathic inflammatory myopathies (IIMs) are a group of rare autoimmune diseases in which several subtypes, primarily dermatomyositis (DM), are associated with a high risk of malignancy. Although the relationship between the pathogenesis o...
Behçet's Disease In Children And Adults Of Sub-Saharan Ancestry: A Systematic Review And Meta-Analysis [0.03%]
贝赫切特病在撒哈拉以南儿童和成人中的系统评价和Meta分析
Benoit Suzon,Arthur Felix,Fabienne Louis-Sidney et al.
Benoit Suzon et al.
Background: The characteristics of Behçet's disease (BD) in individuals of Sub-Saharan ancestry (sub-SA) are poorly understood. Methods: ...
The Role of Solute Carriers in the Metabolic Reprogramming of Skin Diseases [0.03%]
溶质载体在皮肤疾病代谢重编程中的作用
Yihui Chen,Cong Peng,Xiang Chen et al.
Yihui Chen et al.
Inflammatory skin diseases and skin cancers are usually accompanied by metabolic comorbidities or altered metabolic status. Metabolomic analysis indicates that patients with inflammatory skin diseases and skin cancers exhibit altered metabo...
Systemic Psoriasis: From Molecular Mechanisms to Global Management Strategies [0.03%]
系统性银屑病：从分子机制到全球管理策略
Suriyaraj Shanmugasundaram Prema,Deepankumar Shanmugamprema
Suriyaraj Shanmugasundaram Prema
Psoriasis is a chronic, immune-mediated inflammatory disorder marked by a complex interplay between genetic predisposition, cytokine dysregulation, and environmental triggers. Originally perceived as a superficial dermatological condition, ...
Correction: Towards a Multi-omics Understanding of Anaphylaxis: Insights into Pathogenesis and Biomarker Identification [0.03%]
Correction：向多组学的过敏性休克认识迈进：对发病机制和生物标志物识别的新见解
Manca Svetina,Tanja Kunej,Peter Korošec et al.
Manca Svetina et al.
Immunomodulatory Roles of Faecalibacterium prausnitzii and Akkermansia muciniphila in Autoimmune Diseases: Mechanistic Insights and Therapeutic Potential [0.03%]
Faecalibacterium prausnitzii和Akkermansia muciniphila在自身免疫性疾病中发挥的免疫调节作用：机制及治疗潜力的见解
Eui Jeong Han,Ji-Seon Ahn,Yoon Jung Chae et al.
Eui Jeong Han et al.
Alterations in gut microbiota composition are increasingly recognized as key contributors to autoimmune disease pathogenesis. While dominant phyla such as Firmicutes and Bacteroidetes have been extensively studied at the phylum level, the i...
Hongjie Chen,Jing Yang
Hongjie Chen
Decades of research have elucidated diverse aspects of neuroimmunology. This interdisciplinary field originates from the observation almost one century ago that local sensory signals in the skin regulate mast cell degranulation, a key event...
Factors Influencing Treatment Adherence in Chronic Spontaneous Urticaria: A Systematic Review [0.03%]
影响慢性自发性荨麻疹治疗依从性的因素：系统评价研究
Aditya Joshi,Lauren Gawey,Muhammad Rahman et al.
Aditya Joshi et al.
Chronic spontaneous urticaria (CSU) is characterized by recurrent wheals and/or angioedema without an identifiable trigger. Despite advances in therapy-including biologics such as omalizumab-suboptimal treatment adherence remains a major ch...