Proposition for a New Classification of Hypersensitivity Reactions - an Expanded Nomenclature [0.03%]
超敏反应新的分类方案——扩大命名法的提议
Andrea Szegedi,Werner J Pichler,Anikó Kapitány et al.
Andrea Szegedi et al.
Diseases associated with hypersensitivity reactions (HRs) are extremely common and can affect the quality of life of millions of people, sometimes with life-threatening severity. In order to diagnose, treat, cure, or potentially prevent the...
Precision Medicine in Plant Food Allergy: a Systematic Review of Biomarkers Under a Clinical Approach [0.03%]
基于临床方法的植物食物过敏精确诊断标志物系统评价
M L Somoza,E Nuñez-Borque,I M Sánchez-Guerrero et al.
M L Somoza et al.
Plant food allergy (FA) is a major global health problem, being peanut one of the most studied allergenic foods worldwide. Biomarkers (Bms) are essential tools for precision medicine, guiding diagnosis, risk stratification, and treatment. H...
Cytoreduction is a Valid Option for Treatment and Prevention of Anaphylaxis in Systemic Mastocytosis: Case Report and Literature Review [0.03%]
细胞减少术可作为系统性肥大细胞增生症治疗和预防过敏性休克的有效方法：病例报告及文献回顾
Toon Ieven,Inge Govaerts,Glynis Frans et al.
Toon Ieven et al.
Heterogeneity in Atopic Dermatitis: Ethnic, Anatomical Site, and Age-related Variations [0.03%]
特应性皮炎的异质性：种族、解剖部位和年龄相关的差异
Yixuan Liu,Yizhen Li,Liangliang Sun et al.
Yixuan Liu et al.
Yang Li,Xiangzhen Meng,Patrick S C Leung et al.
Yang Li et al.
Autoimmune hepatitis (AIH) is typically a chronic, inflammatory, and progressive liver disease of autoimmune origin. Currently, two recognized types are identified in clinical practice: type 1 and type 2. The disease can occur in all geogra...
The Role of Aryl Hydrocarbon Receptor in Airway Remodeling: Mechanistic Insights Across Cellular Functions [0.03%]
芳烃受体在气道重塑中的作用：跨细胞功能的机制见解
Mohammad Irshad Reza,Ashish Kumar,Rodney D Britt Jr et al.
Mohammad Irshad Reza et al.
Airway remodeling, a hallmark of asthma, involves structural and functional changes in the airways including extracellular matrix (ECM) deposition, airway smooth muscle (ASM) cell hypertrophy and hyperplasia, epithelial and fibroblasts remo...
Neuro-immune Crosstalk in Atopic Dermatitis: A Multiaxial Regulatory Network and Novel Therapeutic Perspectives [0.03%]
特应性皮炎中的神经免疫交叉 talk：多轴调节网络与新的治疗观点
Wanyao Liu,Hanyi Zhang,Xiang Chen et al.
Wanyao Liu et al.
Novel Therapeutic Strategies for Atopic Dermatitis: Biomarker Modulation and Clinical Implications. A Systematic Review [0.03%]
特应性皮炎的新型治疗策略：生物标志物调节及临床意义系统评价研究
Noelia Moreiras-Arias,Juan José Nieto-Fontarigo,Francisco Javier Salgado et al.
Noelia Moreiras-Arias et al.
Advances in the understanding of atopic dermatitis (AD) pathogenesis have driven the development of innovative systemic therapies targeting key immunologic pathways. This systematic review summarizes current evidence on the impact of biolog...
Atopic Comorbidities and Topical Steroids in Early Childhood Atopic Dermatitis: Are We Missing a Piece of the Puzzle? [0.03%]
婴儿期湿疹 topical皮质类固醇和atopic共病：我们遗漏了什么？
Courtney A Chau,Sonya L Cyr,Ruchi Gupta et al.
Courtney A Chau et al.
Model-Based Meta-Analysis of IL-17 A Inhibitors for Moderate-to-Severe Plaque Psoriasis: Establishing Exposure-Response Relationships to Inform Targeted Drug Development [0.03%]
基于模型的IL-17A抑制剂治疗斑块状银屑病中重度患者的Meta分析：建立暴露反应关系以指导靶向药物开发
Yixiao Liu,Xiaoya Chen,Ling Xu et al.
Yixiao Liu et al.
This study aimed to establish an exposure-response model for IL-17 A inhibitors to predict the clinical efficacy of novel agents based on in vitro potency and pharmacokinetic parameters, guiding the development of new IL-17 A-targeting ther...