Regulatory B Cells at the Crossroads of Epigenetic Control and Immune Homeostasis [0.03%]
表观遗传调控与免疫稳态交汇处的调节性B细胞
Duminduni Hewa Angappulige,Darby J Ballard,Christina James Thomas et al.
Duminduni Hewa Angappulige et al.
Regulatory B cells (Bregs) cooperate with FOXP3⁺ regulatory T cells (Tregs) to maintain immune tolerance. Among diverse Breg subsets, IL-10⁺ Bregs are the best-defined mediators of suppression across autoimmunity and cancer. We synthesize...
The Role of Regnase-1 in Autoimmune Diseases - A Future Therapeutic Target for Clinical Use [0.03%]
Regnase-1在自身免疫性疾病中的作用及其作为未来临床治疗靶点的潜力
Minghui Wang,Zhanjun Huang,Xun Gong et al.
Minghui Wang et al.
Management and Immunotherapy for Fungal Allergy: Clinical Practice and Unmet Needs [0.03%]
真菌过敏的管理和免疫疗法：临床实践与未满足的需求
Yongshi Yang,Yangxue Fu,Jinlyu Sun et al.
Yongshi Yang et al.
Advances in Biomarkers and Therapeutic Targets for Idiopathic Inflammatory Myopathies Related Lung Disease [0.03%]
自身免疫性肌炎相关间质性肺病生物标志物和治疗靶点研究进展
Hongzheng Wu,Xiaomeng Li,Honglin Xu et al.
Hongzheng Wu et al.
The Self-amplifying Inflammatory Cascade in Obstetric Antiphospholipid Syndrome: From Pathophysiology to Placenta-centric Immunotherapeutic Targets [0.03%]
obstetric抗磷脂综合征的自我放大炎症级联反应：从病理生理到胎盘免疫治疗靶点
Rui Yan,Yuxin Wei,Lu Chen et al.
Rui Yan et al.
Obstetric Antiphospholipid Syndrome (OAPS) is an autoimmune-driven pregnancy complication whose core pathology is a dysregulated inflammatory cascade at the maternal-fetal interface, rather than the traditionally emphasized thrombosis. Anti...
Therapeutic Potential of Tulisokibart and Anti-TL1A Therapy in Inflammatory Disorders: Current Insights and Future Directions [0.03%]
Tulisokibart和抗TL1A疗法在炎症性疾病中的治疗潜力：当前见解与未来方向
Juling Sia,Bernett Lee,Hazel H Oon
Juling Sia
A Comprehensive Review of IL-10 and IL-10 Receptor Deficiencies: From Basic Science to Clinical Bedside [0.03%]
白细胞介素10和白细胞介素10受体缺陷的全面综述：从基础科学到临床治疗
Jun Xiao,Ziqing Ye,Ying Huang
Jun Xiao
Interleukin 10 (IL-10) is a potent anti-inflammatory cytokine. IL-10 receptor (IL-10R) consists of two chains of ligand-binding IL-10RA and two subunits of IL-10RB. IL-10 and IL-10R play important role in maintaining immune homeostasis in t...
Yingyang Xu,Xiaohong Lyu,Yongshi Yang et al.
Yingyang Xu et al.
Shanshan Li,Zhanling Liang,Muhammad Mazhar et al.
Shanshan Li et al.
Evolving Therapeutic Strategies in ANCA-Associated Vasculitis: Current Standards and Emerging Targets for GPA and MPA [0.03%]
抗中性粒细胞胞浆抗体相关性血管炎治疗策略的演变：GPA和MPA目前的标准及新兴靶点
Roberto Dal Pozzolo,Luca Iorio,Federica Davanzo et al.
Roberto Dal Pozzolo et al.
Granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are severe autoimmune disorders characterized by necrotizing small-vessel inflammation, and are classified among anti-neutrophil cytoplasmic antibody (ANCA)-associate...