Immediate and Delayed Hypersensitivity Reactions to Beta-Lactam Antibiotics [0.03%]
β-内酰胺类抗生素的即刻和迟发超敏反应
Ellen Minaldi,Elizabeth J Phillips,Allison Norton
Ellen Minaldi
Beta-lactam antibiotics are the most commonly reported drug allergy in adults and children. More than 95% of those with reported allergy labels to beta lactams are not confirmed when subjected to allergy testing. Beta lactam antibiotics are...
A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing Immunologist [0.03%]
practicing immunologist的Post-treatment 陆姆病综合症和慢性陆姆病综述
Katelyn H Wong,Eugene D Shapiro,Gary K Soffer
Katelyn H Wong
Lyme disease is an infection caused by Borrelia burgdorferi sensu lato, which is transmitted to humans through the bite of an infected Ixodes tick. The majority of patients recover without complications with antibiotic therapy. However, for...
The Mortality from Hereditary Angioedema Worldwide: a Review of the Real-World Data Literature [0.03%]
全世界遗传性血管性水肿的死亡率：真实世界数据文献回顾
Fernanda Gontijo Minafra,Tifany Rafaely Gonçalves,Thaís Martins Alves et al.
Fernanda Gontijo Minafra et al.
This study aims to review the global mortality secondary to laryngeal edema in patients diagnosed with hereditary angioedema and their relatives over the years, as well as to describe epidemiological and clinical findings associated with th...
Francesca Colapietro,Ana Lleo,Elena Generali
Francesca Colapietro
Anti-mitochondrial antibodies (AMA) are directed against the E2 subunits of the 2-oxo acid dehydrogenase complexes (PDC-E2) and are the typical biomarkers of primary biliary cholangitis (PBC), being present in 90-95% of patients, with incre...
Combining Anti-IgE Monoclonal Antibodies and Oral Immunotherapy for the Treatment of Food Allergy [0.03%]
抗IgE单克隆抗体与口服免疫疗法联手治疗食物过敏
Laurent Guilleminault,Marine Michelet,Laurent Lionel Reber
Laurent Guilleminault
Immunoglobulin E (IgE)-mediated food allergy is a real public health problem worldwide. The prevalence of food allergy is particularly high in children. Patients with food allergy experience high morbidity with a change in quality of life d...
Different Phenotypes in Asthma: Clinical Findings and Experimental Animal Models [0.03%]
哮喘的不同表型：临床发现和动物实验模型
Luiz Otávio Lourenço,Alessandra Mussi Ribeiro,Fernanda Degobbi Tenório Quirino Dos Santos Lopes et al.
Luiz Otávio Lourenço et al.
Asthma is a respiratory allergic disease presenting a high prevalence worldwide, and it is responsible for several complications throughout life, including death. Fortunately, asthma is no longer recognized as a unique manifestation but as ...
Yaqi Wang,Shengxiang Xiao,Yumin Xia et al.
Yaqi Wang et al.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by diverse serological autoantibodies. Anti-dsDNA antibodies are involved in multiple organ damage, especially the kidney, skin, and central nervous system. An...
The Role of IgE in Upper and Lower Airway Disease: More Than Just Allergy! [0.03%]
IgE在上下呼吸道疾病中的作用：不仅仅是过敏！
Philippe Gevaert,Kit Wong,Lauren A Millette et al.
Philippe Gevaert et al.
Immunoglobulin E (IgE) is a well-known key factor in allergic airway disease; however, its central role in non-allergic airway inflammation is often underestimated. In some airway diseases, IgE is produced as a result of allergic sensitizat...
Zhangkai Jason Cheng,Zhiqing Zhan,Mingshan Xue et al.
Zhangkai Jason Cheng et al.
In December 2019, the COVID-19 pandemic quickly spread throughout China and beyond, posing enormous global challenges. With prompt, vigorous, and coordinated control measures, mainland China contained the spread of the epidemic within two m...
T Fulop,A Larbi,G Pawelec et al.
T Fulop et al.
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an evolutionary or rather a revolutionary conceptualization of the immune changes in response to a lifelong stress. This conceptualization permitted to consider t...