Clinical Application of Antibody Immunity Against SARS-CoV-2: Comprehensive Review on Immunoassay and Immunotherapy [0.03%]
针对SARS-CoV-2抗体免疫的临床应用：免疫检测与免疫治疗综述
Zhangkai J Cheng,Bizhou Li,Zhiqing Zhan et al.
Zhangkai J Cheng et al.
The current COVID-19 global pandemic poses immense challenges to global health, largely due to the difficulty to detect infection in the early stages of the disease, as well as the current lack of effective antiviral therapy. Research and u...
Mesenchymal Stem Cell-Based Therapy as a New Approach for the Treatment of Systemic Sclerosis [0.03%]
基于间充质干细胞的治疗作为系统性硬化症治疗的新方法
Xiufen Zhuang,Xiao Hu,Shuren Zhang et al.
Xiufen Zhuang et al.
Systemic sclerosis (SSc) is an intractable autoimmune disease with unmet medical needs. Conventional immunosuppressive therapies have modest efficacy and obvious side effects. Targeted therapies with small molecules and antibodies remain un...
Immunosenescence, Inflammaging, and Frailty: Role of Myeloid Cells in Age-Related Diseases [0.03%]
免疫衰老、炎性老化与衰弱症：髓系细胞在年龄相关性疾病中的作用
Augusto Bleve,Francesca Motta,Barbara Durante et al.
Augusto Bleve et al.
The immune system is the central regulator of tissue homeostasis, ensuring tissue regeneration and protection against both pathogens and the neoformation of cancer cells. Its proper functioning requires homeostatic properties, which are mai...
Drug Allergy Delabeling Programs: Recent Strategies and Targeted Populations [0.03%]
药物过敏去标签计划：近期策略与目标人群
Karen M Anstey,Lulu Tsao,Iris M Otani
Karen M Anstey
Drug allergy delabeling programs have become an essential element of antibiotic stewardship. Development of delabeling programs involves careful selection of target patient population, thoughtful design of delabeling approach, stakeholder e...
Alice Zavatta,Francesca Parisi,Chiara Mandò et al.
Alice Zavatta et al.
During female lifetime and pregnancy, inflammation and cellular senescence are implicated in physiological processes, from ovulation and menstruation, to placental homeostasis and delivery. Several lifestyles, nutritional, and environmental...
Elena Perez
Elena Perez
Over the past 20 years, the rapid evolution in the diagnosis and treatment of primary immunodeficiencies (PI) and the recognition of immune dysregulation as a feature in some have prompted the use of "inborn errors of immunity" (IEI) as a m...
Margaret T Redmond,Rebecca Scherzer,Benjamin T Prince
Margaret T Redmond
The field of Immunology is one that has undergone great expansion in recent years. With the advent of new diagnostic modalities including a variety of genetic tests (discussed elsewhere in this journal), the ability to diagnose a patient wi...
Immune Memory in Aging: a Wide Perspective Covering Microbiota, Brain, Metabolism, and Epigenetics [0.03%]
衰老中的免疫记忆：广泛涵盖微生物组、大脑、代谢和表观遗传学的角度透视
Ozlem Bulut,Gizem Kilic,Jorge Domínguez-Andrés
Ozlem Bulut
Non-specific innate and antigen-specific adaptive immunological memories are vital evolutionary adaptations that confer long-lasting protection against a wide range of pathogens. Adaptive memory is established by memory T and B lymphocytes ...
Does Adjusted Global Antiphospholipid Syndrome Score (aGAPSS) Predict the Obstetric Outcome in Antiphospholipid Antibody Carriers? A Single-Center Study [0.03%]
调整后的全球抗磷脂综合征评分（aGAPSS）能否预测抗磷脂抗体携带者的妊娠结局？一项单中心研究
Sara Del Barrio-Longarela,Víctor M Martínez-Taboada,Pedro Blanco-Olavarri et al.
Sara Del Barrio-Longarela et al.
The adjusted Global Antiphospholipid Syndrome (APS) Score (aGAPSS) is a tool proposed to quantify the risk for antiphospholipid antibody (aPL)-related clinical manifestations. However, aGAPSS has been validated mainly for thrombotic events ...
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole [0.03%]
抗生素的即刻和迟发性过敏反应：氨基糖苷类、克林霉素、利奈唑胺和甲硝唑
Michelle Dilley,Bob Geng
Michelle Dilley
Hypersensitivity reactions including IgE-mediated and delayed cell-mediated reactions to aminoglycosides, clindamycin, linezolid, and metronidazole are rare. For aminoglycosides, allergic contact dermatitis is the most frequent reaction for...