Road Less Traveled: Drug Hypersensitivity to Fluoroquinolones, Vancomycin, Tetracyclines, and Macrolides [0.03%]
氟喹诺酮类、万古霉素、四环素和大环内酯类药物超敏反应的诊疗路径
Linda J Zhu,Anne Y Liu,Priscilla H Wong et al.
Linda J Zhu et al.
While fluoroquinolones, vancomycin, macrolides, and tetracyclines are generally safe antibiotics, they can induce both immediate and delayed hypersensitivity reactions (HSRs). Historically, less has been published on allergies to these anti...
An Italian Multicenter Study on Anti-NXP2 Antibodies: Clinical and Serological Associations [0.03%]
一项意大利多中心关于抗NXP2抗体的研究：临床和血清学关联
Micaela Fredi,Ilaria Cavazzana,Angela Ceribelli et al.
Micaela Fredi et al.
The identification of anti-NXP2 antibodies is considered a serological marker of dermatomyositis (DM), with calcinosis, severe myositis and, in some reports, with cancer. Historically, these associations with anti-NXP2 antibodies have been ...
Advanced Imaging Supports the Mechanistic Role of Autoimmunity and Plaque Rupture in COVID-19 Heart Involvement [0.03%]
先进 imaging 支持自身免疫和斑块破裂在 COVID-19 心脏损伤中的机制作用
Maria Elena Laino,Angela Ammirabile,Francesca Motta et al.
Maria Elena Laino et al.
The cardiovascular system is frequently affected by coronavirus disease-19 (COVID-19), particularly in hospitalized cases, and these manifestations are associated with a worse prognosis. Most commonly, heart involvement is represented by my...
Heart Involvement in Systemic Sclerosis: the Role of Magnetic Resonance Imaging [0.03%]
系统性硬化症的心脏受累：磁共振的作用
Giacomo De Luca,Sara Bombace,Lorenzo Monti
Giacomo De Luca
Systemic sclerosis (SSc) is a severe connective tissue disease characterized by diffuse vascular damage and aberrant activation of immune system, resulting in inflammation and fibrosis of skin and internal organs, including the heart. Cardi...
Xin Huang,Qing Zhang,Huilin Zhang et al.
Xin Huang et al.
Systemic lupus erythematosus (SLE) is a complicated autoimmune disease with female susceptibility. It is characterized by over-activation of the immune system and deposit of autoimmune complex in multiple organs. High heterogeneity, unpredi...
Risk and Protective Factors for COVID-19 Morbidity, Severity, and Mortality [0.03%]
COVID-19患病、严重程度和死亡率的风险及保护因素
Jin-Jin Zhang,Xiang Dong,Guang-Hui Liu et al.
Jin-Jin Zhang et al.
The outbreak of the coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become an evolving global health crisis. Currently, a number of risk factors have been identified...
Identification of Parameters Representative of Immune Dysfunction in Patients with Severe and Fatal COVID-19 Infection: a Systematic Review and Meta-analysis [0.03%]
严重及致命COVID-19感染患者免疫功能障碍表征参数识别：系统回顾和meta分析
Rundong Qin,Li He,Zhaowei Yang et al.
Rundong Qin et al.
Abnormal immunological indicators associated with disease severity and mortality in patients with COVID-19 have been reported in several observational studies. However, there are marked heterogeneities in patient characteristics and researc...
The Conundrum of Psoriatic Arthritis: a Pathogenetic and Clinical Pattern at the Midpoint of Autoinflammation and Autoimmunity [0.03%]
关于银屑病关节炎的难题：自体炎症和自身免疫中心点处的发病机理及临床模式
Rossana Scrivo,Salvatore D&#x;Angelo,Antonio Carriero et al.
Rossana Scrivo et al.
Psoriatic arthritis (PsA) is a chronic inflammatory condition characterized by psoriasis, synovitis, enthesitis, spondylitis, and the possible association with other extra-articular manifestations and comorbidities. It is a multifaceted and...
Maria-Grazia Lazzaroni,Francesca Crisafulli,Liala Moschetti et al.
Maria-Grazia Lazzaroni et al.
Systemic sclerosis (SSc) is a rare systemic autoimmune disease that can influence reproductive health. SSc has a strong female predominance, and the disease onset can occur during fertility age in almost 50% of patients. Preconception couns...
Anti-Ro52 Autoantibody Is Common in Systemic Autoimmune Rheumatic Diseases and Correlating with Worse Outcome when Associated with interstitial lung disease in Systemic Sclerosis and Autoimmune Myositis [0.03%]
抗Ro52自身抗体在系统性自身免疫风湿病中常见并与系统性硬化和自身免疫肌炎中的间质性肺疾病相关联时预后更差
Edward K L Chan
Edward K L Chan
This review highlights the 30 plus years research progress since the discovery of autoantibody to Ro52/TRIM21 in patients with systemic lupus erythematosus (SLE) and Sjögren's syndrome (SjS). After the initial expression cloning of the Ro5...