Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature [0.03%]
自身免疫性肝炎1型的血清生物标志物：CD48的例子及其文献综述
Mingli Hu,Zhengrui You,You Li et al.
Mingli Hu et al.
In autoimmune hepatitis (AIH), the persisting inflammation contributes to fibrosis progression, for which conventional biochemical markers manifest relatively unsatisfactory prediction. Herein, we assessed the value of serum CD48 (sCD48) as...
Renal Disease and Systemic Sclerosis: an Update on Scleroderma Renal Crisis [0.03%]
肾病与系统性硬化症：弥漫性硬皮病肾危象的最新研究进展
Alice Cole,Voon H Ong,Christopher P Denton
Alice Cole
Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc) with a mortality of 20% at 6 months. Once the leading cause of mortality in scleroderma (SSc), it remains a serious complication, often necessitat...
Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes [0.03%]
微生物群失调调节免疫反应以适应过敏性疾病的发展
Tracy Augustine,Manoj Kumar,Souhaila Al Khodor et al.
Tracy Augustine et al.
The hygiene hypothesis has been popularized as an explanation for the rapid increase in allergic disease observed over the past 50 years. Subsequent epidemiological studies have described the protective effects that in utero and early life ...
Grace T Padron,Vivian P Hernandez-Trujillo
Grace T Padron
Primary immunodeficiency (PID) may impact any component of the immune system. The number of PID and immune dysregulation disorders is growing steadily with advancing genetic detection methods. These expansive recognition methods have change...
Inflammaging and Frailty in Immune-Mediated Rheumatic Diseases: How to Address and Score the Issue [0.03%]
免疫介导性风湿病中的炎症衰老与衰弱：如何应对及评估问题
Fausto Salaffi,Andrea Di Matteo,Sonia Farah et al.
Fausto Salaffi et al.
Frailty is a new concept in rheumatology that can help identify people more likely to have less favorable outcomes. Sarcopenia and inflammaging can be regarded as the biological foundations of physical frailty. Frailty is becoming more wide...
Autoantibodies and Cancer Association: the Case of Systemic Sclerosis and Dermatomyositis [0.03%]
自身抗体与癌症的关联：以系统性硬化症和皮肌炎为例
David F Fiorentino,Livia Casciola-Rosen
David F Fiorentino
Several rheumatic diseases have a perplexing association with cancer. Unraveling this mysterious connection is likely to provide deeper understanding regarding mechanisms governing the onset of both autoimmunity and cancer immunity, in addi...
Infections or Vaccines Associated with Finkelstein-Seidlmayer Vasculitis: Systematic Review [0.03%]
与Finkelstein-Seidlmayer血管炎相关的感染或疫苗的系统评价
Gabriel Bronz,Céline Betti,Pietro O Rinoldi et al.
Gabriel Bronz et al.
Finkelstein-Seidlmayer vasculitis, also referred to as acute hemorrhagic edema of young children, is a rare small-vessel leukocytoclastic vasculitis. This condition is skin-limited, mainly affects infants up to 2 years of age and spontaneou...
Allergy to Local Anesthetics is a Rarity: Review of Diagnostics and Strategies for Clinical Management [0.03%]
局部麻醉药过敏是一类极少见的疾病——诊断和临床处理策略综述
Shirley Jiang,Monica Tang
Shirley Jiang
Local anesthetics (LA) are commonly used in procedures and in topical agents for pain management. With the increasing use of LA drugs, the management of LA reactions is more frequently encountered in the office and in operating rooms. True ...
Real-Life Effectiveness of Benralizumab, Mepolizumab and Omalizumab in Severe Allergic Asthma Associated with Nasal Polyps [0.03%]
Benralizumab、Mepolizumab和Omalizumab治疗伴鼻息肉严重过敏性哮喘的疗效分析
Angelica Tiotiu,Paula Mendez-Brea,Iulia Ioan et al.
Angelica Tiotiu et al.
Biological therapies are available for the treatment of the severe allergic asthma (SAA) with blood eosinophil count ≥ 0.3 × 109/L. Several of them also showed benefits on nasal polyps (NP), one of the most frequent comorbidities of the s...
Observational Study
Clinical reviews in allergy & immunology. 2023 Apr;64(2):179-192. DOI:10.1007/s12016-022-08938-w 2023
Thoracic Involvement in Systemic Autoimmune Rheumatic Diseases: Pathogenesis and Management [0.03%]
系统性自身免疫风湿病的胸膜肺受累：发病机制与治疗展望
Elena De Zorzi,Paolo Spagnolo,Elisabetta Cocconcelli et al.
Elena De Zorzi et al.
Thoracic involvement is one of the main determinants of morbidity and mortality in patients with autoimmune rheumatic diseases (ARDs), with different prevalence and manifestations according to the underlying disease. Interstitial lung disea...