Gemma Lepri,Martina Catalano,Silvia Bellando-Randone et al.
Gemma Lepri et al.
The association of systemic sclerosis (SSc) and cancer is well known from several decades suggesting common genetic and environmental risk factors involved in the development of both diseases. Immunosuppressive drugs widely used in SSc may ...
Elisabeth Hodara,Peck Y Ong
Elisabeth Hodara
Eczema herpeticum (EH) is a viral skin infection caused by herpes simplex virus (HSV) superimposed on eczematous skin lesions in atopic dermatitis (AD). Though the pathogenesis of EH has yet to be fully elucidated, the fact that EH is relat...
Pathophysiology, Diagnosis, and Management of Chronic Spontaneous Urticaria: A Literature Review [0.03%]
慢性自发性荨麻疹的病理生理、诊断和治疗：文献回顾
Benjamin Greiner,Savannah Nicks,Michael Adame et al.
Benjamin Greiner et al.
Chronic spontaneous urticaria (CSU) is characterized by recurring wheals that last 6 weeks or longer without an identifiable cause. The estimated point prevalence of CSU worldwide is 1%. Furthermore, it has a significant impact on quality o...
The Treatment of Primary Immune Deficiencies: Lessons Learned and Future Opportunities [0.03%]
原发性免疫缺陷的治疗：经验与展望
Kenneth Paris,Luke A Wall
Kenneth Paris
Primary immunodeficiency is a group of disorders associated with susceptibility to infectious agents and the development of various comorbidities. Many primary immunodeficiencies are complicated by immune dysregulation, autoinflammation, or...
A Summary on the Genetics of Systemic Lupus Erythematosus, Rheumatoid Arthritis, Systemic Sclerosis, and Sjögren's Syndrome [0.03%]
自身免疫性疾病狼疮、类风湿性关节炎、硬化症和舍格伦综合征的遗传学研究进展综述
Lourdes Ortíz-Fernández,Javier Martín,Marta E Alarcón-Riquelme
Lourdes Ortíz-Fernández
Systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and Sjögren's syndrome are four major autoimmune rheumatic diseases characterized by the presence of autoantibodies, caused by a dysregulation of the immune system tha...
Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers [0.03%]
系统性硬化症特异性抗体：新型和经典的生物标志物
Ilaria Cavazzana,Tamara Vojinovic,Paolo Airo&#x; et al.
Ilaria Cavazzana et al.
Disease-specific autoantibodies are considered the most important biomarkers for systemic sclerosis (SSc), due to their ability to stratify patients with different severity and prognosis. Anti-nuclear antibodies (ANA), occurring in subjects...
Francesca Motta,Elisa Barone,Antonio Sica et al.
Francesca Motta et al.
Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age worldwide. While in the past it was considered a mere consequence of cartilage degradation leading to anatomical and functional joint impairment, in ...
Sanchi Chawla,Ankur Kumar Jindal,Kanika Arora et al.
Sanchi Chawla et al.
X-linked agammaglobulinaemia (XLA) is a primary immunodeficiency (PID) resulting from a defect in the B cell development. It has conventionally been thought that T cells play a major role in the development and function of the B cell compar...
Correlates of Protection Against Respiratory Syncytial Virus Infection in Infancy [0.03%]
婴儿期呼吸道合胞病毒感染的保护相关因素
Bahaa Abu-Raya,Frederic Reicherz,Pascal M Lavoie
Bahaa Abu-Raya
The highest morbidity and mortality from respiratory syncytial virus (RSV) infection occurs in young infants. Immunization of expectant mothers during pregnancy has the potential to substantially reduce the burden of RSV disease in a majori...
Germinal Center-Related G Protein-Coupled Receptors in Antibody-Mediated Autoimmune Skin Diseases: from Basic Research to Clinical Trials [0.03%]
自身免疫性皮肤病相关归巢受体的研究进展：从基础到临床
Pengpeng Cao,Ming Yang,Christopher Chang et al.
Pengpeng Cao et al.
Germinal center (GC) reaction greatly contributes to the humoral immune response, which begins in lymph nodes or other secondary lymphoid organs after follicular B cells are activated by T-dependent antigens. The GCs then serve as a platfor...